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The map label for this gene is grsT [H]

Identifier: 126442756

GI number: 126442756

Start: 2495717

End: 2496559

Strand: Reverse

Name: grsT [H]

Synonym: BURPS668_A2592

Alternate gene names: 126442756

Gene position: 2496559-2495717 (Counterclockwise)

Preceding gene: 126444335

Following gene: 126442464

Centisome position: 79.83

GC content: 69.04

Gene sequence:

>843_bases
ATGAGCGCGCGCGAAGCCGCAGCCGAATCGCCTTGGCTGATCGTCCATGAGGCGCGCAACGCGCGCGTGCGGCTCTTCTG
CTTTCACTACGCGGGCGCGACCGCGTCGATCTTCCGAACCTGGCCGGGCGGCCTGCCGGATTGGATCGAAGTCGTCGCGG
TGCAATTGCCGGGCCGCGAGTATCGGCTCGGCGAGCCGCTGATCGAGCACGCGGAGCCGATCGTCGAGGCGCTCGCGGAT
ATCGTGCCGCCGCTGCTCGATCTGCCGTACGCATTCTTCGGTCACAGCATGGGCGCGCTGATCGCATTCGATCTCGCGCA
CCTGCTGCGCGCGCGCGGCTTCGCGCAGCCGTTGCTGTTCGTCGCATCGGGGCGCAGCGCGCCGCGCTTCAGGTGGCGGG
ATGCGGGCATTCAGACGCTGCCCGACGAGGCGTTCATCGCCGCGGTGCGCGACTACAACGGCACGCCGGAAGCGCTGATC
GCCGATCCCGCGCTGCGCGAGCTGTGGCTGCCGAGGCTGCGCGCGGATCTGACGATTTCGGCGACATACCGCTACGTCGG
GCCGCCGCCGCTCGATTGCCCGATGCTGGTGTTGCACGGCTCGAACGACGGCCTCGTCAGCGACGCCGGTTTGTCCGGCT
GGCTCGCCGAGACGATCGGGGCCGTGCGCTATGTCGGCTTTTCCGGCGGCCATTTCTTTATGCACGGCGAGGAAGCAGGT
GTGCTCGCCGAGGTTCGCCGCGAGCTCGAGCGCGTGCTCGCGCGCGCCGCGCAGGATGAGCCGAACGGCATGCGCGAGCC
GGCGGCGCGCATGAGTCATTTGACGGAGGAGAGCGGAACATGA

Upstream 100 bases:

>100_bases
CGATCCAGGATCAGTACTTCGGCATCGTGCGCGGCACGCACGCGGACAAATGGAACTGGCTCACGCCCGTGGCGGTGCCG
TCGCGCGACGGAGCACGGGC

Downstream 100 bases:

>100_bases
AGAGCAAGTCATCGCGCACGCGGGTGGCGATCCTGGGCTCGGGCAGCATCGGGCTCGATCTGATGTTCAAAGTCAAGGCA
TCCGAGCAATTCGATCTGAA

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSAREAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGREYRLGEPLIEHAEPIVEALAD
IVPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLFVASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALI
ADPALRELWLPRLRADLTISATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAG
VLAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESGT

Sequences:

>Translated_280_residues
MSAREAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGREYRLGEPLIEHAEPIVEALAD
IVPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLFVASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALI
ADPALRELWLPRLRADLTISATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAG
VLAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESGT
>Mature_279_residues
SAREAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGREYRLGEPLIEHAEPIVEALADI
VPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLFVASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIA
DPALRELWLPRLRADLTISATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAGV
LAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESGT

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=236, Percent_Identity=30.0847457627119, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI8922871, Length=195, Percent_Identity=31.7948717948718, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 30700; Mature: 30569

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAREAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGRE
CCCHHHHCCCCEEEEEECCCCEEEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHCCCCCC
YRLGEPLIEHAEPIVEALADIVPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEE
VASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIADPALRELWLPRLRADLTIS
EECCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHCCEEEE
ATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAG
EEEEECCCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHEEEEECCCEEEEECCCCC
VLAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESGT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAREAAAESPWLIVHEARNARVRLFCFHYAGATASIFRTWPGGLPDWIEVVAVQLPGRE
CCHHHHCCCCEEEEEECCCCEEEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHCCCCCC
YRLGEPLIEHAEPIVEALADIVPPLLDLPYAFFGHSMGALIAFDLAHLLRARGFAQPLLF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEE
VASGRSAPRFRWRDAGIQTLPDEAFIAAVRDYNGTPEALIADPALRELWLPRLRADLTIS
EECCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHCCEEEE
ATYRYVGPPPLDCPMLVLHGSNDGLVSDAGLSGWLAETIGAVRYVGFSGGHFFMHGEEAG
EEEEECCCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHEEEEECCCEEEEECCCCC
VLAEVRRELERVLARAAQDEPNGMREPAARMSHLTEESGT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]