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The map label for this gene is mhpF [C]

Identifier: 126442464

GI number: 126442464

Start: 2494827

End: 2495720

Strand: Reverse

Name: mhpF [C]

Synonym: BURPS668_A2591

Alternate gene names: 126442464

Gene position: 2495720-2494827 (Counterclockwise)

Preceding gene: 126442756

Following gene: 126445045

Centisome position: 79.8

GC content: 63.42

Gene sequence:

>894_bases
ATGAAGAGCAAGTCATCGCGCACGCGGGTGGCGATCCTGGGCTCGGGCAGCATCGGGCTCGATCTGATGTTCAAAGTCAA
GGCATCCGAGCAATTCGATCTGAAGTTCGTCGTCGGACGCAATGCGAACAGCGACGGGCTGCGGCTCGCGCGCAGTTGCA
ACGTGGAGACATCGAGCGACGGTCTCGATTTCCTGAAGGCGCACGAGGATGCGTACGACCTCGTGTTCGACGCGACATCG
GCCGCCGCGCACAAGGTCAACAACCGCTTCTTCTCCGACGCGGGCAAGTTCGTGATTGATCTGACGCCCGCGAAGGTCGG
CCGCCTGTGCGTGCCGTGCATCAATCTGGACGACATGGGCGCCGAGCAGAACGTGAACCTGATCACCTGCGGCGGGCAGG
CGAGCCTGCCGCTCGCGTACGCGCTGAAGCAGGCGGTCGACGAGATCGATTACCTGGAGGTGGTGTCGGCGATCGCGTCG
CGCAGCGCCGGCATCGCAACGCGCGAGAACATCGACGAATACATGACGACGACCGAGTACGCGCTCGCGAAATTCAGCGG
TGCGAAGAAGACGAAGGCGATCCTCAACATCAATCCGGCCGAGCCCGGTGTGCGGATGCAGACGACGCTCTATGCGTACG
CGCGCTATCGCGATTTCGACCGCGTGCGCGCAAGCGTTGCCGACATGGTCGAGAAGGTGCGCGAATACGTGCCCGGCTAT
CGGCTCGTCGTCGAGCCGCTCGAAAGCCAGGGGAGGATCACGATCGGTCTCACCGTGCGCGGGCGCGGCGATTATCTGCC
CGAGTACGCGGGCAATCTGGACATCATCAACTGCGCGGCGCTCGCGGTCGCCTCGCATCGGCACGCAACCGCCAGACTAG
GAGCCACACAATGA

Upstream 100 bases:

>100_bases
GCGAGCTCGAGCGCGTGCTCGCGCGCGCCGCGCAGGATGAGCCGAACGGCATGCGCGAGCCGGCGGCGCGCATGAGTCAT
TTGACGGAGGAGAGCGGAAC

Downstream 100 bases:

>100_bases
TACTGATCAGCGATGCGACCTTGCGCGACGGCAACCATGCGATTCGTCACCAACTGAGCGCCGCGCAGATACATGCGTAT
GCGCGCGCGGCCGACGAAGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATS
AAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIAS
RSAGIATRENIDEYMTTTEYALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ

Sequences:

>Translated_297_residues
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATS
AAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIAS
RSAGIATRENIDEYMTTTEYALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
>Mature_297_residues
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATS
AAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIAS
RSAGIATRENIDEYMTTTEYALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=301, Percent_Identity=41.8604651162791, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_BURP0 (A3P826)

Other databases:

- EMBL:   CP000573
- RefSeq:   YP_001076486.1
- ProteinModelPortal:   A3P826
- SMR:   A3P826
- STRING:   A3P826
- GeneID:   4904369
- GenomeReviews:   CP000573_GR
- KEGG:   bpl:BURPS1106A_A2455
- TIGR:   BURPS1106A_A2455
- eggNOG:   COG4569
- HOGENOM:   HBG300125
- OMA:   HVKNDAF
- ProtClustDB:   PRK08300
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32288; Mature: 32288

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSD
CCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEHHHCCCCCCCC
GLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMG
CHHHHHHCCCHHHHEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHCCEEEEECCCCCCC
AEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSAGIATRENIDEYMTTTEY
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
HHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
EEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCEEHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure
MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSD
CCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCEEHHHCCCCCCCC
GLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMG
CHHHHHHCCCHHHHEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHCCEEEEECCCCCCC
AEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSAGIATRENIDEYMTTTEY
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGY
HHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
EEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCEEHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA