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The map label for this gene is 126442569

Identifier: 126442569

GI number: 126442569

Start: 1493868

End: 1495397

Strand: Reverse

Name: 126442569

Synonym: BURPS668_A1560

Alternate gene names: NA

Gene position: 1495397-1493868 (Counterclockwise)

Preceding gene: 126445131

Following gene: 126445204

Centisome position: 47.82

GC content: 69.8

Gene sequence:

>1530_bases
ATGGAACTGACGCCCGCGCCGCGCGCCGGCATGCGCGCGCATCGACAAACACCAAGACAAGCGCATCGTTTCGCACGCGT
CATTCGACAAGGAACCATCATGCGTCGCCTCTTGTGCTGCTTCACGATCGTTCTGGGCTTCCTGTTCGCCGCGCCGTCGC
ACGCGGGCGACGCGGCCGCCGTTGGGCAACTGACGGTGGCGCTGTATCCGTGGGTGCCGCGCGTCGACCAGTTCAAGCGC
GCGATCGAAACCGAATGGAAGAAGGCGCAGCCGGGCGTCGCGCTGCGGTTCGTGTCCGCGCACGCGTGGGACGGCGGCTA
CCGGAACGATCCGCCCGCGAGCGCCGACGTCTACGTGTACGACGCGATCTTCCTCGACTATTTCCGCAGCCAGAACTGGC
TCGAGCCGCTCGCGGCGGACGAGATCCAGCACATCGACGATTTCCTGCCGTACGCGATCCAGGGCGTGAAGGCGGGCGAC
CGGTACTACAGCATCCCGCAGCTCGGCTGCGCGAACGTGCTGTTCTACCGGAAGGACGACGCGGCGCTCGCGGCCGCGAC
GACGCTCACGCAGGTGCGCGGCGCGCTCGAGCAATGCACGTTCACGAGCGAGATCCCGCCGGACAGGCGCGGGCTGATGG
TCGACATGTCCGGGCGCACGACGAACGCCGCGCTCTATCTGGACGCCGCGCACAGCCGCACGGGCGCATACCCGCTGCCG
CTGCCGTGGAACGCGAACGACCTGAACGGCGAAGCGCTCGGCAGCCTGCGCGCGCTGATGGCGATGTCGAGCTGGCCGAA
CGCGACGGCCGAGCTGCCCGGCCAGTACGATCGCTCGGTATGGTTCAGCGACGGCGAAGGGCGCGCGGTGATCGGCTATT
CGGAATCGATGTCGGCGATGAGCGAGGCGGCGCGGCGCGATCTCGACTTCAAGTTCCTGCCGCTGTCGGACACGCCGCAG
CCGCCGCTCTTCTACGCGGACGTGATCGGCGTGAACACGACGACCCACGCGCGCGGCACGCGCGCGCTCGCGGTGCAACT
CGCGAACGTGATCGCCGCATCGTCGACGATGGTGCAAAGCGTCGGGCCGGACGGCAGCGGCGTGCCGCAATATCTGTTCT
CCGCGCGGCGCAGCGTGCTGCACACGCTCGCGCAGCGCTATCCGCTCTATCGGAAGATGGTCGCGCTGCTGGATGCGCGC
GAGCCGGTGATGTTCAAGATCGATGCGCAGTCGCGCAACTGGCTCGCCTCGATGAGCGGGCCGATCGCGCAGCGCGCGCG
CGCCGATTACCCGTGCGGCTGCGATATCGACACCGCGCTGCCGATCGCCGACTATCGCGGCGCGCAGGCCGTGTGCCCGA
CCGTCTGCGCGGCGCAGGGCGGCTGGAACGGCCAGTGGACCAATCAGTCTCCCGCGGCGCCCGCCGGGCAGTCGGCGTGC
GGCTGCAACGCGTGCCCGACGTCAGCCGCGGCGAAGCTGCCGCGCGCGCTCGCCACCCGCGCCGCGCCCGGCGATCGCGC
GAAGCCGTGA

Upstream 100 bases:

>100_bases
GCGTCTGCCAAGCCAAGGCTTACCTGAGCGACGCGCTCGCCGCGTCGGGCGAGCTCGAGGTCGGTCGCGGGCACGGCCCG
GTCCATCATTTCCACGCGCT

Downstream 100 bases:

>100_bases
CACGGGCGGCGCCCGGCCTCGCCGCGGGCCGGGCCGGGCGCCCGGCCCGCGAGGCCCGCGCCGCGCCCGAATCGCCTCGC
GCGCGGTCGAACGCGGTTGC

Product: putative thiaminase I

Products: NA

Alternate protein names: Thiaminase I; Thiamine pyridinylase [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MELTPAPRAGMRAHRQTPRQAHRFARVIRQGTIMRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKR
AIETEWKKAQPGVALRFVSAHAWDGGYRNDPPASADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGD
RYYSIPQLGCANVLFYRKDDAALAAATTLTQVRGALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLP
LPWNANDLNGEALGSLRALMAMSSWPNATAELPGQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQ
PPLFYADVIGVNTTTHARGTRALAVQLANVIAASSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAR
EPVMFKIDAQSRNWLASMSGPIAQRARADYPCGCDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSAC
GCNACPTSAAAKLPRALATRAAPGDRAKP

Sequences:

>Translated_509_residues
MELTPAPRAGMRAHRQTPRQAHRFARVIRQGTIMRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKR
AIETEWKKAQPGVALRFVSAHAWDGGYRNDPPASADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGD
RYYSIPQLGCANVLFYRKDDAALAAATTLTQVRGALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLP
LPWNANDLNGEALGSLRALMAMSSWPNATAELPGQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQ
PPLFYADVIGVNTTTHARGTRALAVQLANVIAASSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAR
EPVMFKIDAQSRNWLASMSGPIAQRARADYPCGCDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSAC
GCNACPTSAAAKLPRALATRAAPGDRAKP
>Mature_509_residues
MELTPAPRAGMRAHRQTPRQAHRFARVIRQGTIMRRLLCCFTIVLGFLFAAPSHAGDAAAVGQLTVALYPWVPRVDQFKR
AIETEWKKAQPGVALRFVSAHAWDGGYRNDPPASADVYVYDAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGD
RYYSIPQLGCANVLFYRKDDAALAAATTLTQVRGALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLP
LPWNANDLNGEALGSLRALMAMSSWPNATAELPGQYDRSVWFSDGEGRAVIGYSESMSAMSEAARRDLDFKFLPLSDTPQ
PPLFYADVIGVNTTTHARGTRALAVQLANVIAASSTMVQSVGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAR
EPVMFKIDAQSRNWLASMSGPIAQRARADYPCGCDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSAC
GCNACPTSAAAKLPRALATRAAPGDRAKP

Specific function: Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: =2.5.1.2 [H]

Molecular weight: Translated: 55251; Mature: 55251

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTPAPRAGMRAHRQTPRQAHRFARVIRQGTIMRRLLCCFTIVLGFLFAAPSHAGDAAA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VGQLTVALYPWVPRVDQFKRAIETEWKKAQPGVALRFVSAHAWDGGYRNDPPASADVYVY
HHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEH
DAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGDRYYSIPQLGCANVLFYRKDD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEECCC
AALAAATTLTQVRGALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCC
LPWNANDLNGEALGSLRALMAMSSWPNATAELPGQYDRSVWFSDGEGRAVIGYSESMSAM
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECHHHHHHH
SEAARRDLDFKFLPLSDTPQPPLFYADVIGVNTTTHARGTRALAVQLANVIAASSTMVQS
HHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAREPVMFKIDAQSRNWLASMSG
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCC
PIAQRARADYPCGCDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSAC
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GCNACPTSAAAKLPRALATRAAPGDRAKP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MELTPAPRAGMRAHRQTPRQAHRFARVIRQGTIMRRLLCCFTIVLGFLFAAPSHAGDAAA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VGQLTVALYPWVPRVDQFKRAIETEWKKAQPGVALRFVSAHAWDGGYRNDPPASADVYVY
HHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEH
DAIFLDYFRSQNWLEPLAADEIQHIDDFLPYAIQGVKAGDRYYSIPQLGCANVLFYRKDD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEEECCC
AALAAATTLTQVRGALEQCTFTSEIPPDRRGLMVDMSGRTTNAALYLDAAHSRTGAYPLP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCC
LPWNANDLNGEALGSLRALMAMSSWPNATAELPGQYDRSVWFSDGEGRAVIGYSESMSAM
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECHHHHHHH
SEAARRDLDFKFLPLSDTPQPPLFYADVIGVNTTTHARGTRALAVQLANVIAASSTMVQS
HHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VGPDGSGVPQYLFSARRSVLHTLAQRYPLYRKMVALLDAREPVMFKIDAQSRNWLASMSG
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCC
PIAQRARADYPCGCDIDTALPIADYRGAQAVCPTVCAAQGGWNGQWTNQSPAAPAGQSAC
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GCNACPTSAAAKLPRALATRAAPGDRAKP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8631946; 9843405 [H]