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The map label for this gene is rsmC

Identifier: 126209459

GI number: 126209459

Start: 2230377

End: 2231366

Strand: Reverse

Name: rsmC

Synonym: APL_2005

Alternate gene names: 126209459

Gene position: 2231366-2230377 (Counterclockwise)

Preceding gene: 126209464

Following gene: 126209457

Centisome position: 98.1

GC content: 41.01

Gene sequence:

>990_bases
ATGCTCTCTCTTGAAAGTGAAGTATTAACCCGTCATTTACCGCTATTTGCCAATAAATCCATTTTACTTTTTGGTGATGT
TAGAGATCGATTTGCCGATCAAATAAAAGCGAATGCGAAAAGCGTTGCTGTTTTTAGCAGTTATTTCGATTATGCACGCC
AATATGCCGATGTGAGCTTTGGCTTATATTGCGAAATTAAAGCCGAATTAGCAGTTTTTTACTGGACTAAAAACAAACAG
GAATGCCAATATCAATTACTGCAATGGCTTTCACAAGTCGATGTCGGGCAAGAAATGTTGATTATCGGTGAAAACCGTGC
CGGTGTACGTTCAGTAGAAAAATTACTTGAACCTTACGGCAATATTGCCAAAATTGACTCGGCTCGTCGCTGCGGGTTAT
ATCATTTTGAGTTGCAAAGCGTACCGGACTTTGATGGTAAAAAATTCTGGAAATCTTACCGCTTGCAAGATCTCAATATC
TTCGCTTTACCGGCGGTATTCAGTTCGGCAGAGTTAGACGGCGGCACACAATTATTATTATCTACTTTTAATAAGGCAGA
CCGCTTGAAGGGCAAAGTATTGGATCTTGGTTGTGGAGCCGGTGTTATCGGTGCAAGCCTCAAACAGCAATTTGAAAAAA
TTAAATTAACCATGTCCGATATTCACGCAATGGCATTGGAATCCTCTCGCCGTACGTTTGCGGAAAATGCGCTGGATGGA
ACGGTTGTGGCAAGCGATGTCTTTTCAAATATCGAAGAACGTTTTGATTTGATTGTGTCTAATCCGCCGTTTCACGATGG
GATTGATACCGCTTATCGTGCGGTAGAAGATTTAATTGCTCAAGCAAAACAGCGTTTAAATCGAGGTGGGGAATTACGTA
TTGTGGCGAACGCTTTCTTACCTTATCCGGATTTATTGGACAAAGCTTTCGGTTCGCATCAGGTTATCGCCAAATCGAAC
AAATTTAAAGTATATTCGGCAAAAGCATAA

Upstream 100 bases:

>100_bases
TACCTCGCAAAAACAAGTAGGGAATAGTACCAAAAGTCGGTAAAATGCGGAAATGTTTTTATGATTACGCTCCGTAATAT
TCAGAAATAAAAGGATATTT

Downstream 100 bases:

>100_bases
CCTCTCTTACAAAAAGACGGTCAGAAGCTCCTTTTCAACCGTCTTTTAAAACAACCTGACACTCCTGTTTCTAACGTCTC
AATCATTAAAAACCGTCTAA

Product: 16S ribosomal RNA m2G1207 methyltransferase

Products: NA

Alternate protein names: 16S rRNA m2G1207 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rsmC

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MLSLESEVLTRHLPLFANKSILLFGDVRDRFADQIKANAKSVAVFSSYFDYARQYADVSFGLYCEIKAELAVFYWTKNKQ
ECQYQLLQWLSQVDVGQEMLIIGENRAGVRSVEKLLEPYGNIAKIDSARRCGLYHFELQSVPDFDGKKFWKSYRLQDLNI
FALPAVFSSAELDGGTQLLLSTFNKADRLKGKVLDLGCGAGVIGASLKQQFEKIKLTMSDIHAMALESSRRTFAENALDG
TVVASDVFSNIEERFDLIVSNPPFHDGIDTAYRAVEDLIAQAKQRLNRGGELRIVANAFLPYPDLLDKAFGSHQVIAKSN
KFKVYSAKA

Sequences:

>Translated_329_residues
MLSLESEVLTRHLPLFANKSILLFGDVRDRFADQIKANAKSVAVFSSYFDYARQYADVSFGLYCEIKAELAVFYWTKNKQ
ECQYQLLQWLSQVDVGQEMLIIGENRAGVRSVEKLLEPYGNIAKIDSARRCGLYHFELQSVPDFDGKKFWKSYRLQDLNI
FALPAVFSSAELDGGTQLLLSTFNKADRLKGKVLDLGCGAGVIGASLKQQFEKIKLTMSDIHAMALESSRRTFAENALDG
TVVASDVFSNIEERFDLIVSNPPFHDGIDTAYRAVEDLIAQAKQRLNRGGELRIVANAFLPYPDLLDKAFGSHQVIAKSN
KFKVYSAKA
>Mature_329_residues
MLSLESEVLTRHLPLFANKSILLFGDVRDRFADQIKANAKSVAVFSSYFDYARQYADVSFGLYCEIKAELAVFYWTKNKQ
ECQYQLLQWLSQVDVGQEMLIIGENRAGVRSVEKLLEPYGNIAKIDSARRCGLYHFELQSVPDFDGKKFWKSYRLQDLNI
FALPAVFSSAELDGGTQLLLSTFNKADRLKGKVLDLGCGAGVIGASLKQQFEKIKLTMSDIHAMALESSRRTFAENALDG
TVVASDVFSNIEERFDLIVSNPPFHDGIDTAYRAVEDLIAQAKQRLNRGGELRIVANAFLPYPDLLDKAFGSHQVIAKSN
KFKVYSAKA

Specific function: Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmC family

Homologues:

Organism=Escherichia coli, GI1790830, Length=329, Percent_Identity=47.4164133738602, Blast_Score=303, Evalue=9e-84,
Organism=Escherichia coli, GI87082206, Length=224, Percent_Identity=32.5892857142857, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMC_ACTP2 (A3N3U3)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054684.1
- ProteinModelPortal:   A3N3U3
- SMR:   A3N3U3
- STRING:   A3N3U3
- GeneID:   4848821
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_2005
- eggNOG:   COG2813
- HOGENOM:   HBG296757
- OMA:   TKNKQEC
- PhylomeDB:   A3N3U3
- ProtClustDB:   PRK09489
- BioCyc:   APLE416269:APL_2005-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01862
- InterPro:   IPR002052
- InterPro:   IPR013675
- InterPro:   IPR007848

Pfam domain/function: PF05175 MTS; PF08468 MTS_N

EC number: =2.1.1.172

Molecular weight: Translated: 36896; Mature: 36896

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLESEVLTRHLPLFANKSILLFGDVRDRFADQIKANAKSVAVFSSYFDYARQYADVSF
CCCCHHHHHHHHCCHHCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCE
GLYCEIKAELAVFYWTKNKQECQYQLLQWLSQVDVGQEMLIIGENRAGVRSVEKLLEPYG
EEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCC
NIAKIDSARRCGLYHFELQSVPDFDGKKFWKSYRLQDLNIFALPAVFSSAELDGGTQLLL
CEECCCCCHHCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEHHHHHCCCCCCCCHHHHH
STFNKADRLKGKVLDLGCGAGVIGASLKQQFEKIKLTMSDIHAMALESSRRTFAENALDG
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TVVASDVFSNIEERFDLIVSNPPFHDGIDTAYRAVEDLIAQAKQRLNRGGELRIVANAFL
HHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
PYPDLLDKAFGSHQVIAKSNKFKVYSAKA
CCHHHHHHHCCCCEEEEECCCEEEEEECC
>Mature Secondary Structure
MLSLESEVLTRHLPLFANKSILLFGDVRDRFADQIKANAKSVAVFSSYFDYARQYADVSF
CCCCHHHHHHHHCCHHCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCE
GLYCEIKAELAVFYWTKNKQECQYQLLQWLSQVDVGQEMLIIGENRAGVRSVEKLLEPYG
EEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCC
NIAKIDSARRCGLYHFELQSVPDFDGKKFWKSYRLQDLNIFALPAVFSSAELDGGTQLLL
CEECCCCCHHCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEHHHHHCCCCCCCCHHHHH
STFNKADRLKGKVLDLGCGAGVIGASLKQQFEKIKLTMSDIHAMALESSRRTFAENALDG
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TVVASDVFSNIEERFDLIVSNPPFHDGIDTAYRAVEDLIAQAKQRLNRGGELRIVANAFL
HHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
PYPDLLDKAFGSHQVIAKSNKFKVYSAKA
CCHHHHHHHCCCCEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA