Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 126209367

GI number: 126209367

Start: 2138730

End: 2140175

Strand: Reverse

Name: xylB [H]

Synonym: APL_1907

Alternate gene names: 126209367

Gene position: 2140175-2138730 (Counterclockwise)

Preceding gene: 126209368

Following gene: 126209366

Centisome position: 94.1

GC content: 46.4

Gene sequence:

>1446_bases
ATGTATATCGGAATTGATTTAGGCACCTCAGGCGTTAAAGTCGTTTTACTCAATGAATCTCAAGAAATCATCGCAACCAC
ACATCAATCTTTACCTATTTCTCGCCCTCATCCGCTTTGGTCGGAACAAAATCCGGAAGACTGGTGGCACGCAACCAATT
TAGCTATGCTCGCTTTAGCACAGCAACAGGATTTAACCGCCGTTAAAGCGATCGGCTTAACCGGTCAAATGCACGGTGCG
ACTTTATTGGATAAGCATGACCAAGTATTGAGTCCGGCAATTTTGTGGAATGACGGTCGTAGCTTTGCGGAGTGTGCCGA
ATTGGAATCATTAGTACCGAATAGCCGTGAGATTACCGGTAATCTGATGATGCCGGGCTTTACCGCACCGAAATTAAAAT
GGGTGGATAAGCATCAGCCGCAAATCGCCGAACAAATGGATAAAGTCTTACTGCCGAAAGATTATTTACGTTTACGTATG
ACCGGCGAATATGCCTCCGATATGTCGGATGCCTCCGGCACAATGTGGTTGGATGTCGGTAAAAGAGATTGGAATCAGGC
GTTACTGAATGCGTGCGGACTTGACGTTAGCAATATGCCTAAACTGTTTGAAGGTAATCAAATTACCGGTTACTTACGTC
CTGAATTGGCAAAAAGCTGGAAATTAAATACCGTTCCGGTAATTGCCGGTGGCGGTGATAATGCCGCCGGAGCCATTGGT
ATCGGGCTTTACCAATCCGGACAAGCGATGTTATCACTCGGTACGTCGGGTGTGTATTTTGTGGTAACCGATAAATTCAG
TGCCAATCCGCAAAAAGCGGTACACAGTTTCTGCCATGCGTTACCGGATCGTTGGCACTTGATGTCGGTCATGCTCAGTG
CCGCATCAGCGGTCGATTTTGCCCAAAAAGTTACCGGTATTAGCGATATTAAAACCTTATTCCAACAAGTCGAAAACTGC
AACCAAGCGAGCGATGCGATTTTCCTTCCTTATTTATCCGGCGAACGTACACCGCATAATGACCCTTATGCCAAAGGTGT
ATTCTGGGGCTTAACCCATAACGATAACCCGATTACGATGGCAAAAGCTGCGGTGGAAGGGGTCAGTTTTGCATTAGCAG
ACGGTATTGATGTGTTACACGAAACCGGTGTGAAAGCGGATAATATCGCCCTGATCGGTGGCGGAGCGAAAAGCGCTTAT
TGGCGACAACTGTTAGCAGATATTACCGGCAGAACCTTTGAATATCGTACCGGCGGTGATGTCGGCCCGGCTTTAGGAGC
AGCGAAACTAGCGCAGATTGCCTTAAATCCGAATGAAGATATTGCCAATTTCTGTCAGCCGTTACCGCTTGAAGCGGTTT
ACCAACCTAATCGCAGCAAGTTTGCCGAATACCAAGACAAGCGGTCAAAATTTGCTGAAATTTACCAAAGATTAAAAGGT
CTTTAA

Upstream 100 bases:

>100_bases
TGCAATATGGCGTATTTTATTTCATTGATTATGCTTATATCGCAATCAAATCTCCCCCAGCCCCTCTTTTCTAAAGAGGG
GAGTTCTCTTAGGAGGCTTT

Downstream 100 bases:

>100_bases
TGCTCTGAAAGCCAGCCCGTTCAATGCGAACGGGCTTTTTTTTCCGTTTTATTCAAAAATCTGACAAAAATTTATTTCAC
GCCCTTGATCATTTCATTTT

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MYIGIDLGTSGVKVVLLNESQEIIATTHQSLPISRPHPLWSEQNPEDWWHATNLAMLALAQQQDLTAVKAIGLTGQMHGA
TLLDKHDQVLSPAILWNDGRSFAECAELESLVPNSREITGNLMMPGFTAPKLKWVDKHQPQIAEQMDKVLLPKDYLRLRM
TGEYASDMSDASGTMWLDVGKRDWNQALLNACGLDVSNMPKLFEGNQITGYLRPELAKSWKLNTVPVIAGGGDNAAGAIG
IGLYQSGQAMLSLGTSGVYFVVTDKFSANPQKAVHSFCHALPDRWHLMSVMLSAASAVDFAQKVTGISDIKTLFQQVENC
NQASDAIFLPYLSGERTPHNDPYAKGVFWGLTHNDNPITMAKAAVEGVSFALADGIDVLHETGVKADNIALIGGGAKSAY
WRQLLADITGRTFEYRTGGDVGPALGAAKLAQIALNPNEDIANFCQPLPLEAVYQPNRSKFAEYQDKRSKFAEIYQRLKG
L

Sequences:

>Translated_481_residues
MYIGIDLGTSGVKVVLLNESQEIIATTHQSLPISRPHPLWSEQNPEDWWHATNLAMLALAQQQDLTAVKAIGLTGQMHGA
TLLDKHDQVLSPAILWNDGRSFAECAELESLVPNSREITGNLMMPGFTAPKLKWVDKHQPQIAEQMDKVLLPKDYLRLRM
TGEYASDMSDASGTMWLDVGKRDWNQALLNACGLDVSNMPKLFEGNQITGYLRPELAKSWKLNTVPVIAGGGDNAAGAIG
IGLYQSGQAMLSLGTSGVYFVVTDKFSANPQKAVHSFCHALPDRWHLMSVMLSAASAVDFAQKVTGISDIKTLFQQVENC
NQASDAIFLPYLSGERTPHNDPYAKGVFWGLTHNDNPITMAKAAVEGVSFALADGIDVLHETGVKADNIALIGGGAKSAY
WRQLLADITGRTFEYRTGGDVGPALGAAKLAQIALNPNEDIANFCQPLPLEAVYQPNRSKFAEYQDKRSKFAEIYQRLKG
L
>Mature_481_residues
MYIGIDLGTSGVKVVLLNESQEIIATTHQSLPISRPHPLWSEQNPEDWWHATNLAMLALAQQQDLTAVKAIGLTGQMHGA
TLLDKHDQVLSPAILWNDGRSFAECAELESLVPNSREITGNLMMPGFTAPKLKWVDKHQPQIAEQMDKVLLPKDYLRLRM
TGEYASDMSDASGTMWLDVGKRDWNQALLNACGLDVSNMPKLFEGNQITGYLRPELAKSWKLNTVPVIAGGGDNAAGAIG
IGLYQSGQAMLSLGTSGVYFVVTDKFSANPQKAVHSFCHALPDRWHLMSVMLSAASAVDFAQKVTGISDIKTLFQQVENC
NQASDAIFLPYLSGERTPHNDPYAKGVFWGLTHNDNPITMAKAAVEGVSFALADGIDVLHETGVKADNIALIGGGAKSAY
WRQLLADITGRTFEYRTGGDVGPALGAAKLAQIALNPNEDIANFCQPLPLEAVYQPNRSKFAEYQDKRSKFAEIYQRLKG
L

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=435, Percent_Identity=24.1379310344828, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI189409120, Length=434, Percent_Identity=24.4239631336406, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4504007, Length=434, Percent_Identity=24.4239631336406, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI88196792, Length=509, Percent_Identity=20.2357563850688, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1789987, Length=479, Percent_Identity=62.839248434238, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI1790361, Length=474, Percent_Identity=21.9409282700422, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790005, Length=497, Percent_Identity=22.5352112676056, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787789, Length=410, Percent_Identity=26.5853658536585, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1789168, Length=420, Percent_Identity=23.8095238095238, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=436, Percent_Identity=24.7706422018349, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17554530, Length=333, Percent_Identity=22.5225225225225, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864214, Length=450, Percent_Identity=22.4444444444444, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21356607, Length=496, Percent_Identity=23.7903225806452, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24654573, Length=377, Percent_Identity=23.6074270557029, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920476, Length=503, Percent_Identity=24.2544731610338, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357867, Length=529, Percent_Identity=21.3610586011342, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24656367, Length=520, Percent_Identity=21.3461538461538, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656372, Length=388, Percent_Identity=22.1649484536082, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52483; Mature: 52483

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00933 FGGY_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGIDLGTSGVKVVLLNESQEIIATTHQSLPISRPHPLWSEQNPEDWWHATNLAMLALA
CEEEEEECCCCEEEEEECCCCCEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QQQDLTAVKAIGLTGQMHGATLLDKHDQVLSPAILWNDGRSFAECAELESLVPNSREITG
HHCCCHHHHHHCCCCCCCCCHHHCCCHHHHCCEEEECCCCCHHHHHHHHHHCCCCCEEEC
NLMMPGFTAPKLKWVDKHQPQIAEQMDKVLLPKDYLRLRMTGEYASDMSDASGTMWLDVG
CEECCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHEEEEECCCHHHCCCCCCCEEEEECC
KRDWNQALLNACGLDVSNMPKLFEGNQITGYLRPELAKSWKLNTVPVIAGGGDNAAGAIG
CCHHHHHHHHHHCCCHHCCCCHHCCCEEEEEECHHHHHCCCCCCEEEEECCCCCCCCEEE
IGLYQSGQAMLSLGTSGVYFVVTDKFSANPQKAVHSFCHALPDRWHLMSVMLSAASAVDF
EEEECCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AQKVTGISDIKTLFQQVENCNQASDAIFLPYLSGERTPHNDPYAKGVFWGLTHNDNPITM
HHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCHH
AKAAVEGVSFALADGIDVLHETGVKADNIALIGGGAKSAYWRQLLADITGRTFEYRTGGD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCC
VGPALGAAKLAQIALNPNEDIANFCQPLPLEAVYQPNRSKFAEYQDKRSKFAEIYQRLKG
CCHHHHHHHHHHEECCCCHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure
MYIGIDLGTSGVKVVLLNESQEIIATTHQSLPISRPHPLWSEQNPEDWWHATNLAMLALA
CEEEEEECCCCEEEEEECCCCCEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QQQDLTAVKAIGLTGQMHGATLLDKHDQVLSPAILWNDGRSFAECAELESLVPNSREITG
HHCCCHHHHHHCCCCCCCCCHHHCCCHHHHCCEEEECCCCCHHHHHHHHHHCCCCCEEEC
NLMMPGFTAPKLKWVDKHQPQIAEQMDKVLLPKDYLRLRMTGEYASDMSDASGTMWLDVG
CEECCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHEEEEECCCHHHCCCCCCCEEEEECC
KRDWNQALLNACGLDVSNMPKLFEGNQITGYLRPELAKSWKLNTVPVIAGGGDNAAGAIG
CCHHHHHHHHHHCCCHHCCCCHHCCCEEEEEECHHHHHCCCCCCEEEEECCCCCCCCEEE
IGLYQSGQAMLSLGTSGVYFVVTDKFSANPQKAVHSFCHALPDRWHLMSVMLSAASAVDF
EEEECCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AQKVTGISDIKTLFQQVENCNQASDAIFLPYLSGERTPHNDPYAKGVFWGLTHNDNPITM
HHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCHH
AKAAVEGVSFALADGIDVLHETGVKADNIALIGGGAKSAYWRQLLADITGRTFEYRTGGD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCC
VGPALGAAKLAQIALNPNEDIANFCQPLPLEAVYQPNRSKFAEYQDKRSKFAEIYQRLKG
CCHHHHHHHHHHEECCCCHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]