Click here to switch to the map view.

The map label for this gene is xylA

Identifier: 126209368

GI number: 126209368

Start: 2140373

End: 2141692

Strand: Reverse

Name: xylA

Synonym: APL_1908

Alternate gene names: 126209368

Gene position: 2141692-2140373 (Counterclockwise)

Preceding gene: 126209375

Following gene: 126209367

Centisome position: 94.16

GC content: 41.82

Gene sequence:

>1320_bases
ATGTCTAACTATTTCGATAAAATTGAAAAAGTAAAATATGAAGGTGCTGACTCAACCAATCCTTTTGCTTTTAAACATTA
CAATCCGAACGAAGTGATTTTAGGCAAAACCATGGCGGAACATTTACGTTTAGCGGTGTGTTATTGGCATACTTTCTGCT
GGACGGGGAATGATATGTTCGGCGTTGGTTCTTTAGATCGTAGTTGGCAAAAAACGGGCGATTTGCTTGAAGGCGCAAAA
CAAAAAGCGGAAATCGCCTTTGAATTCTTCCAAAAATTAGGAATTCCTTACTATTGCTTCCACGATGTGGATATTGCGCC
GGAAGGCAATTCATATAAAGAATATGTACATAATTTCCACACTATGGTGGATATTCTTGAGAAAAAACAAGCGGAAACCG
GTGTGAAATTATTATGGGGTACGGCAAACTGCTTTACCAACCCTCGTTATATGTCCGGCGCATCAACCAATCCGAATCCG
GAAGTATTCTCTTGGGCGGCATCGCAAGTATTCAATGCGATGAATGCAACCAAACGATTAGGCGGCGAAAACTATGTGTT
ATGGGGCGGTCGTGAAGGTTATGAAACCTTATTAAATACCGATTTAAAACGTGAACGTGAACAAATCGGTCGCTTTATGC
AAATGGTGGTGGAACATAAACACAAAATCGGCTTTAACGGTACGTTATTAATCGAACCGAAACCACAAGAACCGACTAAA
CACCAATATGACTATGACGTAGCAACCGTTTACGGCTTCTTAAAACAATTCGGCTTAGAAAAAGAAATCAAAGTAAATAT
TGAAGCAAACCACGCAACCTTAGCCGGTCATACTTTCCAACACGAAATCGCAACCGCAGCGGCATTAGATATCTTCGGTT
CGATTGATGCCAACCGCGGTGATCCGCAATTAGGTTGGGATACCGACCAATTCCCGAACAGCGTAGAAGAAAATACGCTC
GTGATGTATGAAATCTTAAAAGCGGGCGGATTTACCACCGGCGGCTTCAACTTCGATGCGAAAATCCGTCGCCAAAGTAC
CGACCCGTATGATTTATTCCACGGTCATATCGGAGCGATTGACGTGCTTGCGCTTTCACTTAAACGTGCGGCGAAAATGA
TTGAAGATAAAACCTTACAAGGTATTGTTGATCAACGTTACGCAGGCTGGAACGGCGATTTAGGTCAGCAAATTCTTGCC
GGTAAAGCAAGCCTTGAAGATTTAGCGAAAATCGTTGAAAGCAAAGCGCTTGATCCGAAACCGGTTTCAGGTCAGCAAGA
ATATTTAGAAAATTTAGTGAATAATTATATTTATCGTTAA

Upstream 100 bases:

>100_bases
AATCAAAACCGAAAAACTAAATAACATAATTGAACCGTGTTTTAATTTTCATCATTATGCTCTCGTTTTCAAAATCCATT
GATTCACAGGAGAATTAATT

Downstream 100 bases:

>100_bases
TTATTATTGTAGGGGGACAAGATCCCCCTCTTTAGTAAAGAGGGGTTAGGGGAGATTTGTTTAAAAGGTTAATTTACATT
GTTTAAGTAAGTCTTTTTGC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSNYFDKIEKVKYEGADSTNPFAFKHYNPNEVILGKTMAEHLRLAVCYWHTFCWTGNDMFGVGSLDRSWQKTGDLLEGAK
QKAEIAFEFFQKLGIPYYCFHDVDIAPEGNSYKEYVHNFHTMVDILEKKQAETGVKLLWGTANCFTNPRYMSGASTNPNP
EVFSWAASQVFNAMNATKRLGGENYVLWGGREGYETLLNTDLKREREQIGRFMQMVVEHKHKIGFNGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHTFQHEIATAAALDIFGSIDANRGDPQLGWDTDQFPNSVEENTL
VMYEILKAGGFTTGGFNFDAKIRRQSTDPYDLFHGHIGAIDVLALSLKRAAKMIEDKTLQGIVDQRYAGWNGDLGQQILA
GKASLEDLAKIVESKALDPKPVSGQQEYLENLVNNYIYR

Sequences:

>Translated_439_residues
MSNYFDKIEKVKYEGADSTNPFAFKHYNPNEVILGKTMAEHLRLAVCYWHTFCWTGNDMFGVGSLDRSWQKTGDLLEGAK
QKAEIAFEFFQKLGIPYYCFHDVDIAPEGNSYKEYVHNFHTMVDILEKKQAETGVKLLWGTANCFTNPRYMSGASTNPNP
EVFSWAASQVFNAMNATKRLGGENYVLWGGREGYETLLNTDLKREREQIGRFMQMVVEHKHKIGFNGTLLIEPKPQEPTK
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHTFQHEIATAAALDIFGSIDANRGDPQLGWDTDQFPNSVEENTL
VMYEILKAGGFTTGGFNFDAKIRRQSTDPYDLFHGHIGAIDVLALSLKRAAKMIEDKTLQGIVDQRYAGWNGDLGQQILA
GKASLEDLAKIVESKALDPKPVSGQQEYLENLVNNYIYR
>Mature_438_residues
SNYFDKIEKVKYEGADSTNPFAFKHYNPNEVILGKTMAEHLRLAVCYWHTFCWTGNDMFGVGSLDRSWQKTGDLLEGAKQ
KAEIAFEFFQKLGIPYYCFHDVDIAPEGNSYKEYVHNFHTMVDILEKKQAETGVKLLWGTANCFTNPRYMSGASTNPNPE
VFSWAASQVFNAMNATKRLGGENYVLWGGREGYETLLNTDLKREREQIGRFMQMVVEHKHKIGFNGTLLIEPKPQEPTKH
QYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHTFQHEIATAAALDIFGSIDANRGDPQLGWDTDQFPNSVEENTLV
MYEILKAGGFTTGGFNFDAKIRRQSTDPYDLFHGHIGAIDVLALSLKRAAKMIEDKTLQGIVDQRYAGWNGDLGQQILAG
KASLEDLAKIVESKALDPKPVSGQQEYLENLVNNYIYR

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=438, Percent_Identity=73.972602739726, Blast_Score=710, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_ACTP2 (A3N3K2)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054593.1
- ProteinModelPortal:   A3N3K2
- SMR:   A3N3K2
- STRING:   A3N3K2
- GeneID:   4849662
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1908
- eggNOG:   COG2115
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- PhylomeDB:   A3N3K2
- ProtClustDB:   PRK05474
- BioCyc:   APLE416269:APL_1908-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49636; Mature: 49505

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 101-101 ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYFDKIEKVKYEGADSTNPFAFKHYNPNEVILGKTMAEHLRLAVCYWHTFCWTGNDMF
CCHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHEECCCCEE
GVGSLDRSWQKTGDLLEGAKQKAEIAFEFFQKLGIPYYCFHDVDIAPEGNSYKEYVHNFH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCCHHHHHHHHHH
TMVDILEKKQAETGVKLLWGTANCFTNPRYMSGASTNPNPEVFSWAASQVFNAMNATKRL
HHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGENYVLWGGREGYETLLNTDLKREREQIGRFMQMVVEHKHKIGFNGTLLIEPKPQEPTK
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHTFQHEIATAAALDIFGSIDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCCCCCC
DPQLGWDTDQFPNSVEENTLVMYEILKAGGFTTGGFNFDAKIRRQSTDPYDLFHGHIGAI
CCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHCCCCHHH
DVLALSLKRAAKMIEDKTLQGIVDQRYAGWNGDLGQQILAGKASLEDLAKIVESKALDPK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCC
PVSGQQEYLENLVNNYIYR
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNYFDKIEKVKYEGADSTNPFAFKHYNPNEVILGKTMAEHLRLAVCYWHTFCWTGNDMF
CHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHEECCCCEE
GVGSLDRSWQKTGDLLEGAKQKAEIAFEFFQKLGIPYYCFHDVDIAPEGNSYKEYVHNFH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCCHHHHHHHHHH
TMVDILEKKQAETGVKLLWGTANCFTNPRYMSGASTNPNPEVFSWAASQVFNAMNATKRL
HHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GGENYVLWGGREGYETLLNTDLKREREQIGRFMQMVVEHKHKIGFNGTLLIEPKPQEPTK
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
HQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHTFQHEIATAAALDIFGSIDANRG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCCCCCC
DPQLGWDTDQFPNSVEENTLVMYEILKAGGFTTGGFNFDAKIRRQSTDPYDLFHGHIGAI
CCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHCCCCHHH
DVLALSLKRAAKMIEDKTLQGIVDQRYAGWNGDLGQQILAGKASLEDLAKIVESKALDPK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCC
PVSGQQEYLENLVNNYIYR
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA