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The map label for this gene is lgt

Identifier: 126209355

GI number: 126209355

Start: 2126510

End: 2127304

Strand: Reverse

Name: lgt

Synonym: APL_1895

Alternate gene names: 126209355

Gene position: 2127304-2126510 (Counterclockwise)

Preceding gene: 126209356

Following gene: 126209354

Centisome position: 93.53

GC content: 44.15

Gene sequence:

>795_bases
ATGAACGAACAATTTATTCAATTTCCACAAATTGACCCGATTATTTTTAGTATCGGTCCAATCGCTTTGCGTTGGTACGG
TTTAATGTATTTAATCGGCTTCGGTTTCGCCTATTGGCTTGGTATGCGCCGTGCAAAAAACTCCAACGGCGTTTGGACAA
CCGAACAAGTTGATCAGCTTATCTATACTTGCTTTTGGGGCGTTATATTAGGCGGACGAATCGGCGACGTATTTTTCTAT
AATTTCGACCGCTTGTTACAAGACCCGATGTTCTTATTCCGTATTTGGGAAGGCGGAATGTCATTCCACGGCGGTTTGAT
CGGTGTAATTGTCGCGATGATTTGGGTTTCTTTCCGCCAAAAACGTAGTTTCTGGAATACGGCAGATTTTATCGCACCGT
TGATTCCGTTCGGGCTTGGAATGGGGCGTATCGGTAACTTTATCAATGATGAACTTTGGGGACGTATCACTGATGTGCCT
TGGGCGGTATTATTCCCAAGCGGCGGTTACTTACCTCGTCACCCTTCGCAACTCTATGAGTTTTTCCTAGAAGGTGTGGT
ACTGTTCTTCATCTTAAACTGGTTTATCAAAAAGCCCCGTCCGGCAGGTTCGGTAGCAGGACTGTTCTTAATCGGTTACA
GTGTGTTCCGCTTCTTAGTCGAATATGTACGTGATATCGACCCGAACGTAAATACGGTAGATGATTTGATTACCCGAGGT
CAGTTATTATCGTTACCAATGATTATCGGCGGACTGGCGATTATGATCTGGGCATATTCTCGTAAAAAAGCATAA

Upstream 100 bases:

>100_bases
TTTGCGGTGATGTTGGTTGCGATAGCGATTAATATGTTTGTAAAATAATGCGACGTTTGCTCCCCTCTGTATCAGAGGGG
AATTTTTTTAAAGGAATAAT

Downstream 100 bases:

>100_bases
CGATAAGCGGTTGAATTCGTTAGAAATTTTGCAAATTTCCGATGAAATTCAACCGCTTTTTTGCTGCCCGAATTCTGCGA
GCTTGATCGAAAAGACACAA

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNEQFIQFPQIDPIIFSIGPIALRWYGLMYLIGFGFAYWLGMRRAKNSNGVWTTEQVDQLIYTCFWGVILGGRIGDVFFY
NFDRLLQDPMFLFRIWEGGMSFHGGLIGVIVAMIWVSFRQKRSFWNTADFIAPLIPFGLGMGRIGNFINDELWGRITDVP
WAVLFPSGGYLPRHPSQLYEFFLEGVVLFFILNWFIKKPRPAGSVAGLFLIGYSVFRFLVEYVRDIDPNVNTVDDLITRG
QLLSLPMIIGGLAIMIWAYSRKKA

Sequences:

>Translated_264_residues
MNEQFIQFPQIDPIIFSIGPIALRWYGLMYLIGFGFAYWLGMRRAKNSNGVWTTEQVDQLIYTCFWGVILGGRIGDVFFY
NFDRLLQDPMFLFRIWEGGMSFHGGLIGVIVAMIWVSFRQKRSFWNTADFIAPLIPFGLGMGRIGNFINDELWGRITDVP
WAVLFPSGGYLPRHPSQLYEFFLEGVVLFFILNWFIKKPRPAGSVAGLFLIGYSVFRFLVEYVRDIDPNVNTVDDLITRG
QLLSLPMIIGGLAIMIWAYSRKKA
>Mature_264_residues
MNEQFIQFPQIDPIIFSIGPIALRWYGLMYLIGFGFAYWLGMRRAKNSNGVWTTEQVDQLIYTCFWGVILGGRIGDVFFY
NFDRLLQDPMFLFRIWEGGMSFHGGLIGVIVAMIWVSFRQKRSFWNTADFIAPLIPFGLGMGRIGNFINDELWGRITDVP
WAVLFPSGGYLPRHPSQLYEFFLEGVVLFFILNWFIKKPRPAGSVAGLFLIGYSVFRFLVEYVRDIDPNVNTVDDLITRG
QLLSLPMIIGGLAIMIWAYSRKKA

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=285, Percent_Identity=55.7894736842105, Blast_Score=311, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_ACTP2 (A3N3I9)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054580.1
- STRING:   A3N3I9
- GeneID:   4849918
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1895
- eggNOG:   COG0682
- HOGENOM:   HBG450278
- OMA:   NGELYGK
- PhylomeDB:   A3N3I9
- ProtClustDB:   PRK00052
- BioCyc:   APLE416269:APL_1895-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 30372; Mature: 30372

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1eb4c640)-; HASH(0x1f2c254c)-; HASH(0x1f29839c)-; HASH(0x1e9aa448)-; HASH(0x1e949c20)-; HASH(0x1dd0f888)-; HASH(0x1f2dd6b0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA