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The map label for this gene is trpS [H]

Identifier: 126209352

GI number: 126209352

Start: 2124119

End: 2124982

Strand: Reverse

Name: trpS [H]

Synonym: APL_1892

Alternate gene names: 126209352

Gene position: 2124982-2124119 (Counterclockwise)

Preceding gene: 126209353

Following gene: 126209350

Centisome position: 93.43

GC content: 41.32

Gene sequence:

>864_bases
TTGCGTAAAGCCTCTTTAGACGTATTAGCGCTTTATTTAGCTTGCGGTATTGATCCGAATAAAAGCACGATTTTCATTCA
ATCGCACGTACCGGAACATACTCAATTAGCCTGGGTGTTAAATTGCTACACTTATTTCGGTGAAATGAGCCGTATGACCC
AATTTAAAGATAAATCGGCACGTTATGAAGAAAACGTAAATGTCGGCTTATTTACTTATCCGGTATTAATGGCGGCGGAT
ATTTTGCTTTATCAGGCAAATCAAGTACCGGTCGGCGATGACCAAAAACAACACTTAGAAATTACTCGTGATATTGCCAA
CCGTTTTAATGCGTTATACGGTAAAAAAGATGCGGAAGGTAATGTACTTGAGCCGGTTTTCCAAGTGCCGGAAGTTTTTA
TCGGTAAAGCCGGTGCGCGAGTGATGTCCTTACTTGAACCGACCAAAAAAATGTCGAAATCGGATGAGAATCGTAATAAC
GTCATCGGTTTATTAGAAGACCCGAAAGCGGTTGCGAAGAAAATCAAACGTGCGATGACCGATGGCGATGAGCCGCCTGT
AGTACGTTACGACCGTGAAAATAAAGCCGGCGTATCAAACTTATTAGATATTCTTTCTGCAGTCAGCGGTAAAGCGATTG
CCGAATTAGAAGCCGAATTTGAAGGCAAAATGTACGGTCACTTGAAAACCGAAGTGGCGAAACAAGTTTCTTCATTATTA
ACCGATCTTCAAGAACGTTATAACCACTTCCGTCAAGATGAAGCGTTACTCGAAAGAATCTTCCGTGAAGGTGCGGAAAA
AGCGAGAGTTCGAGCAAGAAAAACACTTGATGAAGTGTATAAATTAGTTGGTTTCGTACAATAA

Upstream 100 bases:

>100_bases
TAGGCGCACTGCGTAACTGGGTGAAAATGCAGACGATTACGATTGCCTTTTCTGTATTGTCGATTTACACGCCATTACTG
TACGCCAAGATCCGGCAGCA

Downstream 100 bases:

>100_bases
TTCTTAAAAGAAAATGCCCCTGTAAGTGAGATACAAGGGCATTTTTGTAGATTTTCGCGAAATATGACCGCTTATTTTAA
TAAATCTTTCAGACTGGATT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MRKASLDVLALYLACGIDPNKSTIFIQSHVPEHTQLAWVLNCYTYFGEMSRMTQFKDKSARYEENVNVGLFTYPVLMAAD
ILLYQANQVPVGDDQKQHLEITRDIANRFNALYGKKDAEGNVLEPVFQVPEVFIGKAGARVMSLLEPTKKMSKSDENRNN
VIGLLEDPKAVAKKIKRAMTDGDEPPVVRYDRENKAGVSNLLDILSAVSGKAIAELEAEFEGKMYGHLKTEVAKQVSSLL
TDLQERYNHFRQDEALLERIFREGAEKARVRARKTLDEVYKLVGFVQ

Sequences:

>Translated_287_residues
MRKASLDVLALYLACGIDPNKSTIFIQSHVPEHTQLAWVLNCYTYFGEMSRMTQFKDKSARYEENVNVGLFTYPVLMAAD
ILLYQANQVPVGDDQKQHLEITRDIANRFNALYGKKDAEGNVLEPVFQVPEVFIGKAGARVMSLLEPTKKMSKSDENRNN
VIGLLEDPKAVAKKIKRAMTDGDEPPVVRYDRENKAGVSNLLDILSAVSGKAIAELEAEFEGKMYGHLKTEVAKQVSSLL
TDLQERYNHFRQDEALLERIFREGAEKARVRARKTLDEVYKLVGFVQ
>Mature_287_residues
MRKASLDVLALYLACGIDPNKSTIFIQSHVPEHTQLAWVLNCYTYFGEMSRMTQFKDKSARYEENVNVGLFTYPVLMAAD
ILLYQANQVPVGDDQKQHLEITRDIANRFNALYGKKDAEGNVLEPVFQVPEVFIGKAGARVMSLLEPTKKMSKSDENRNN
VIGLLEDPKAVAKKIKRAMTDGDEPPVVRYDRENKAGVSNLLDILSAVSGKAIAELEAEFEGKMYGHLKTEVAKQVSSLL
TDLQERYNHFRQDEALLERIFREGAEKARVRARKTLDEVYKLVGFVQ

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=286, Percent_Identity=37.4125874125874, Blast_Score=198, Evalue=5e-51,
Organism=Homo sapiens, GI41352700, Length=135, Percent_Identity=45.1851851851852, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1789786, Length=286, Percent_Identity=74.1258741258741, Blast_Score=449, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI71982800, Length=287, Percent_Identity=33.7979094076655, Blast_Score=177, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71982793, Length=287, Percent_Identity=33.7979094076655, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320474, Length=299, Percent_Identity=37.4581939799331, Blast_Score=189, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24666151, Length=286, Percent_Identity=37.4125874125874, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 32448; Mature: 32448

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKASLDVLALYLACGIDPNKSTIFIQSHVPEHTQLAWVLNCYTYFGEMSRMTQFKDKSA
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYEENVNVGLFTYPVLMAADILLYQANQVPVGDDQKQHLEITRDIANRFNALYGKKDAEG
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
NVLEPVFQVPEVFIGKAGARVMSLLEPTKKMSKSDENRNNVIGLLEDPKAVAKKIKRAMT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHC
DGDEPPVVRYDRENKAGVSNLLDILSAVSGKAIAELEAEFEGKMYGHLKTEVAKQVSSLL
CCCCCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TDLQERYNHFRQDEALLERIFREGAEKARVRARKTLDEVYKLVGFVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKASLDVLALYLACGIDPNKSTIFIQSHVPEHTQLAWVLNCYTYFGEMSRMTQFKDKSA
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYEENVNVGLFTYPVLMAADILLYQANQVPVGDDQKQHLEITRDIANRFNALYGKKDAEG
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
NVLEPVFQVPEVFIGKAGARVMSLLEPTKKMSKSDENRNNVIGLLEDPKAVAKKIKRAMT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHC
DGDEPPVVRYDRENKAGVSNLLDILSAVSGKAIAELEAEFEGKMYGHLKTEVAKQVSSLL
CCCCCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TDLQERYNHFRQDEALLERIFREGAEKARVRARKTLDEVYKLVGFVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA