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The map label for this gene is hslV

Identifier: 126209200

GI number: 126209200

Start: 1972361

End: 1972882

Strand: Reverse

Name: hslV

Synonym: APL_1736

Alternate gene names: 126209200

Gene position: 1972882-1972361 (Counterclockwise)

Preceding gene: 126209201

Following gene: 126209199

Centisome position: 86.74

GC content: 41.95

Gene sequence:

>522_bases
ATGACAACAATCGTATGTGTTCGTAAAGATGGCAAAGTCGCTATCGGCGGTGACGGACAAGCAACGCTAGGTAATTGTGT
AGAAAAAGGCACGGTACGCAAAGTACGCCGTATGTATAAAGATAAAGTGGTAACCGGTTTTGCAGGTTCAACTGCCGATG
CGTTTATCTTACGTGATTTATTCGAGAAAAAATTAGAATTACACCAAGGTCACTTAATCAAATCTGCGGTGGAACTGGCA
AAAGAATGGCGTACCGAACGTTCACTACGCAAATTAGAAGCGATGATGATTGTGGCAAACGAAAGTGAATTTTTACTGGT
TTCAGGATCAGGAGATGTGATTGAACCGGAACAAGATGTACTTGCAATCGGCTCTGGCGGTAACTATGCCAAAGCAGCGG
CACTTGCGCTACTTCGCACCGAAAACAATTTATCCGCAAAAGAAATCGTAGCGGAAGCATTAAAAATCGCCGGTGATATT
GATATTTACTCAAATCATAATCACGTAATCGAAGAAGTTTAA

Upstream 100 bases:

>100_bases
GCAATTTTCCTGTGAAATCTGACCGCTTATCCTTGAAAAAGGCAAATTTTCCCCCATTTAACACCCCAGTTTTCCCTAAA
ATAAAGGACAAGGATTTAAT

Downstream 100 bases:

>100_bases
AAAATGTCCCCCTCTTTGCTAAAGAGGGGGAGTTATTTAGAAGGAACAAAAAATATGTCAATGACCCCTCGTGAAATCGT
GTCGGAATTGGACGCGCACA

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTTIVCVRKDGKVAIGGDGQATLGNCVEKGTVRKVRRMYKDKVVTGFAGSTADAFILRDLFEKKLELHQGHLIKSAVELA
KEWRTERSLRKLEAMMIVANESEFLLVSGSGDVIEPEQDVLAIGSGGNYAKAAALALLRTENNLSAKEIVAEALKIAGDI
DIYSNHNHVIEEV

Sequences:

>Translated_173_residues
MTTIVCVRKDGKVAIGGDGQATLGNCVEKGTVRKVRRMYKDKVVTGFAGSTADAFILRDLFEKKLELHQGHLIKSAVELA
KEWRTERSLRKLEAMMIVANESEFLLVSGSGDVIEPEQDVLAIGSGGNYAKAAALALLRTENNLSAKEIVAEALKIAGDI
DIYSNHNHVIEEV
>Mature_172_residues
TTIVCVRKDGKVAIGGDGQATLGNCVEKGTVRKVRRMYKDKVVTGFAGSTADAFILRDLFEKKLELHQGHLIKSAVELAK
EWRTERSLRKLEAMMIVANESEFLLVSGSGDVIEPEQDVLAIGSGGNYAKAAALALLRTENNLSAKEIVAEALKIAGDID
IYSNHNHVIEEV

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=173, Percent_Identity=65.8959537572254, Blast_Score=236, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_ACTP2 (A3N334)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054425.1
- ProteinModelPortal:   A3N334
- SMR:   A3N334
- STRING:   A3N334
- MEROPS:   T01.006
- GeneID:   4849526
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1736
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   A3N334
- ProtClustDB:   PRK05456
- BioCyc:   APLE416269:APL_1736-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 18811; Mature: 18680

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 2-2

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIVCVRKDGKVAIGGDGQATLGNCVEKGTVRKVRRMYKDKVVTGFAGSTADAFILRDL
CCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FEKKLELHQGHLIKSAVELAKEWRTERSLRKLEAMMIVANESEFLLVSGSGDVIEPEQDV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCE
LAIGSGGNYAKAAALALLRTENNLSAKEIVAEALKIAGDIDIYSNHNHVIEEV
EEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHCC
>Mature Secondary Structure 
TTIVCVRKDGKVAIGGDGQATLGNCVEKGTVRKVRRMYKDKVVTGFAGSTADAFILRDL
CEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
FEKKLELHQGHLIKSAVELAKEWRTERSLRKLEAMMIVANESEFLLVSGSGDVIEPEQDV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCE
LAIGSGGNYAKAAALALLRTENNLSAKEIVAEALKIAGDIDIYSNHNHVIEEV
EEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA