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The map label for this gene is rpoB

Identifier: 126209191

GI number: 126209191

Start: 1957228

End: 1961256

Strand: Direct

Name: rpoB

Synonym: APL_1727

Alternate gene names: 126209191

Gene position: 1957228-1961256 (Clockwise)

Preceding gene: 126209190

Following gene: 126209192

Centisome position: 86.05

GC content: 43.44

Gene sequence:

>4029_bases
ATGGCATATTCATATTCCGAGAAAAAGCGTATTCGTAAGAGCTTTGGTAAACGTCCACAAGTTCTTAACGTACCTTATCT
ATTAACAATTCAGCTTGATTCTTACGAGAAATTTATTCAAAGAGATTCAGATGGACAACAAGGTTTAGAAGCGGCATTCC
GTTCTGTGTTCCCGATTGTAAGCAACAACGGAAGCACTGAATTACAATACGTTTCTTACGAATTAGGAGAGCCGGTATTT
GATGTTCGTGAATGTCAAATTCGCGGTACAACCTATGCGGCACCATTACGCGTTAAACTTCGTTTAGTGACTTTCGACCG
TGAAGCGGCGGCAGGCACTGTAAAAGATATTAAAGAACAAAACGTGTATATGGGCGAAATCCCATTAATGACCGACAACG
GTACTTTCGTGATCAACGGTACCGAGCGTGTAATCGTTTCTCAATTACACCGTAGTCCGGGCGTATTCTTCGATTCCGAC
AAAGGTAAAACCCACTCATCAGGTAAAGTGCTTTATAACGCACGTATTATTCCTTACCGTGGTTCTTGGTTGGATTTCGA
GTTTGACCCGAAAGACAATCTTTATGCACGTATCGACCGCCGTCGTAAATTACCGGCAACCATTATTTTACGTGCATTAG
GTTACACTACCGAAGAAATCTTATCGATGTTCTTCGACAAAGTGAACTTTGAAATCCAAGATAATAAATTATTAATGACG
TTAGTGCCGGAACGTTTACGTGGTGAAACCGCTGCGTTCGATATTGAAGCGAACGGCAAAGTTTACGTTGAACGTGGTCG
TCGTATTACTGCACGTCATATTCGTACATTAGAAAAAGACGGCATTACTCAAATTGAAGTACCGGTAGAGTACATCGTCG
GTAAAGTAGCGGCGAAAGATTACGTTGATCTTTCAACCGGAGAAGTGGTTTGCCCAGCGAATATGGAAATCTCAATGGAG
ATGTTGGCGAAATTATCGCAAGCAGGCTACAAAGAGATCGAAGTACTATTTACTAACGACTTAGATCACGGTCCGTATAT
TTCTGAAACTTTACGTGTCGATCCGACTTATGACCGCTTAAGTGCATTAGTAGAAATCTACCGTATGATGCGTCCGGGCG
AGCCACCGACAAAAGAAGCGGCGGAAGCGTTATTCGACAATATGTTCTTCTCAGCAGACCGTTATGACTTATCGGCAGTT
GGTCGTATGAAGTTCAACCGTTCGTTAAATCTTGAAGAAGGCGTAGGTTCAGGCATTTTAAGTAATGACGACATTACCGG
CGTGATGAAGAAATTAATTGAAATCCGTAACGGTCGTGGCGAAGTGGACGATATCGACCACTTAGGTAACCGTCGTATTC
GTTCGGTAGGCGAAATGGCTGAAAACCAATTCCGTATCGGTTTAGTGCGTGTAGAACGTGCCGTGCGTGAGCGTTTATCA
TTAGGCGATTTAGACGGCATTACTCCGCAAGATTTAATTAATGCGAAGCCGATTTCTGCGGCAGTGAAAGAGTTCTTCGG
TTCTTCACAACTTTCGCAATTTATGGACCAAAATAACCCGCTTTCGGAGGTTACCCATAAACGTCGTATTTCAGCATTAG
GTCCGGGCGGTTTAACCCGCGAACGTGCAGGCTTTGAGGTTCGAGACGTACATACTACTCACTATGGTCGTTTATGTCCG
ATCGAAACCCCTGAAGGTCCGAACATCGGTTTGATCAACTCACTTTCAGTATATGCGCGTACTAATAACTACGGTTTCTT
AGAAACGCCGTTCCGTAAAGTAGTGAACGGTCAAGTAACCGAAGATATTGAGTATTTATCGGCAATCGAAGAAGGTAACT
ACGTTATCGCTCAGGCTAACTCAAACTTAGATGAGAATTTCCGTTTTACCGATACTTACGTAACTTGTCGTGGCGAACAC
GGTGAGTCAGGTTTATACAAACCGGAAGATATTCACTATATGGATATCTCAACACAACAAGTGGTTTCTGTTGCGGCAGC
GTTAATTCCGTTCCTTGAGCATGACGATGCGAACCGTGCGTTAATGGGTGCGAACATGCAACGTCAGGCTGTTCCGACAT
TACGTGCGGATAAACCGTTAGTCGGTACCGGTATGGAAAAACCAATCGCACTTGACTCAGGTGTAGCGATTGTGGCGAAA
CGTGGTGGTATCGTTCAACGTGTTGATGCCTCTCGTATCGTAGTGAAAGTAAACGAAGATGAAACGATTCCGGGCGAAGC
GGGTATCGACATCTATAACTTAATTAAATATACCCGTTCAAATCAAAATACCTGTATCAACCAAATTCCTTGTGTGAATT
TAGGCGAGCCGGTAGCACGTGGCGAGATCTTAGCGGACGGTCCTTCAACAGATTTAGGTGAATTAGCATTAGGTCAAAAT
ATTCGTGTGGCATTCATGCCATGGAACGGTTATAACTTCGAAGACTCAATGTTAGTTTCTGAGCGTGTAGTACAAGAAGA
TCGTTTCACGACAATCCACATCCAAGAGCTATCTTGTGTGGCACGTGATACCAAACTTGGTGCGGAAGAAATTACAGCGG
ATATCCCGAACGTAGGCGAATCGGCATTAAGCAAACTTGATGAATCAGGTATCGTTTACGTGGGTGCGGAAGTTAAAGGC
GGCGACATCTTAGTTGGTAAAGTAACGCCTAAAGGCGAAACCCAATTAACGCCGGAAGAAAAACTTTTACGTGCGATCTT
CGGTGAGAAAGCATCTGATGTTAAAGATTCTTCATTACGTGTACCAAACGGTACTTCAGGTACGGTTATTGACGTTCAAG
TATTTACTCGTGACGGCGTTGAAAAAGATAAACGTGCGTTAGAAATCGAGGAAATGCAGCTTAAAGAAGCGAAGAAAGAT
TTAACTGAAGAGTTAGAAATTTTAGAAGCCGGTTTATTTACTCGTGTTCGCAATTTATTAATCGAAGGCGGCGTATCTGA
AGCTGAATTAGATAAAGTTGCTCGTGAGAAATGGTTAGAACAAACCTTAGATGACGAAGCGAAACAAAATCAATTAGAAC
AGCTTGCGGAACAGCACGAAGAGTTACGTAAAGAGTTTGAACGTAAACTTGAAATTAAACGCAACAAGATCATCCAAGGT
GACGATTTAGCACCGGGTGTGTTAAAAGTGGTTAAAGTTTACTTAGCGGTTCGTCGCCAAATCCAACCGGGTGATAAAAT
GGCGGGTCGTCACGGTAACAAAGGTGTTATCTCGAAAATCAACCCGGTTGAAGATATGCCGTACGATGAAAACGGCCAAC
CGGTTGAGATCGTATTGAACCCGCTGGGCGTACCTTCACGTATGAACATCGGTCAGATCTTAGAAACGCACTTAGGTTTA
GCGGCGAAAGGTATCGGCGACCAAATTAACGCAATGATCAAACAACAACAATCTGTTGCGAAATTGCGTGAATATATCCA
AAAAGCATACGATTTAGGTCACGGCTCACAATCTGTGGATTTAAGCACCTTTACCGATGAAGAAGTAATGCGTTTAGCAG
AAAACTTACGTAAAGGTTTACCGCTTGCAACACCGGTATTCGACGGTGCACACGAAAGCGAAATCAAAGGCTTATTAGAA
TTAGGCGGCTTACCGACTTCAGGCCAAATTACCTTATTTGACGGTCGTACCGGTGAGAAATTCGAGCGTCCTGTAACCGT
AGGTTATATGTATATGCTCAAATTGAACCACTTAGTTGACGACAAAATGCACGCGCGTTCAACCGGTTCTTATAGTCTTG
TTACTCAACAACCGCTTGGTGGTAAAGCACAATTCGGTGGTCAGCGTTTCGGTGAGATGGAGGTTTGGGCATTAGAAGCA
TACGGTGCCGCTTATACCTTACAAGAAATGCTAACGGTTAAATCGGATGACGTGAACGGTCGTACGAAGATGTATAAAAA
CATCGTGGACGGCACACATCAAATGGAACCGGGTATGCCGGAATCATTCAACGTATTGTTGAAAGAGATTCGTGCCTTAG
GTATTGATATGGAGCTTGACGAAGAATAA

Upstream 100 bases:

>100_bases
ATGACACCTCGTACAAATTTAATGCCACTTCCAGCCCGTTCAAATGACGGTCGGATTGTGTAACCTCAACCAAATAAGAA
AATCAGAAGGCTATCTAGCA

Downstream 100 bases:

>100_bases
TCGTCAGCCGTAAAGCGGTCGAATTTGGTAAAAATTTTGCAAAATTTGACCGTTTGTAAAATAGATTTCCTCGTTTAGAG
CCTTGTGTTCTAAGCAAAAC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1342; Mature: 1341

Protein sequence:

>1342_residues
MAYSYSEKKRIRKSFGKRPQVLNVPYLLTIQLDSYEKFIQRDSDGQQGLEAAFRSVFPIVSNNGSTELQYVSYELGEPVF
DVRECQIRGTTYAAPLRVKLRLVTFDREAAAGTVKDIKEQNVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYARIDRRRKLPATIILRALGYTTEEILSMFFDKVNFEIQDNKLLMT
LVPERLRGETAAFDIEANGKVYVERGRRITARHIRTLEKDGITQIEVPVEYIVGKVAAKDYVDLSTGEVVCPANMEISME
MLAKLSQAGYKEIEVLFTNDLDHGPYISETLRVDPTYDRLSALVEIYRMMRPGEPPTKEAAEALFDNMFFSADRYDLSAV
GRMKFNRSLNLEEGVGSGILSNDDITGVMKKLIEIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVRERLS
LGDLDGITPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHTTHYGRLCP
IETPEGPNIGLINSLSVYARTNNYGFLETPFRKVVNGQVTEDIEYLSAIEEGNYVIAQANSNLDENFRFTDTYVTCRGEH
GESGLYKPEDIHYMDISTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAIVAK
RGGIVQRVDASRIVVKVNEDETIPGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGEPVARGEILADGPSTDLGELALGQN
IRVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLKEAKKD
LTEELEILEAGLFTRVRNLLIEGGVSEAELDKVAREKWLEQTLDDEAKQNQLEQLAEQHEELRKEFERKLEIKRNKIIQG
DDLAPGVLKVVKVYLAVRRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGL
AAKGIGDQINAMIKQQQSVAKLREYIQKAYDLGHGSQSVDLSTFTDEEVMRLAENLRKGLPLATPVFDGAHESEIKGLLE
LGGLPTSGQITLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA
YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGTHQMEPGMPESFNVLLKEIRALGIDMELDEE

Sequences:

>Translated_1342_residues
MAYSYSEKKRIRKSFGKRPQVLNVPYLLTIQLDSYEKFIQRDSDGQQGLEAAFRSVFPIVSNNGSTELQYVSYELGEPVF
DVRECQIRGTTYAAPLRVKLRLVTFDREAAAGTVKDIKEQNVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYARIDRRRKLPATIILRALGYTTEEILSMFFDKVNFEIQDNKLLMT
LVPERLRGETAAFDIEANGKVYVERGRRITARHIRTLEKDGITQIEVPVEYIVGKVAAKDYVDLSTGEVVCPANMEISME
MLAKLSQAGYKEIEVLFTNDLDHGPYISETLRVDPTYDRLSALVEIYRMMRPGEPPTKEAAEALFDNMFFSADRYDLSAV
GRMKFNRSLNLEEGVGSGILSNDDITGVMKKLIEIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVRERLS
LGDLDGITPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHTTHYGRLCP
IETPEGPNIGLINSLSVYARTNNYGFLETPFRKVVNGQVTEDIEYLSAIEEGNYVIAQANSNLDENFRFTDTYVTCRGEH
GESGLYKPEDIHYMDISTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAIVAK
RGGIVQRVDASRIVVKVNEDETIPGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGEPVARGEILADGPSTDLGELALGQN
IRVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLKEAKKD
LTEELEILEAGLFTRVRNLLIEGGVSEAELDKVAREKWLEQTLDDEAKQNQLEQLAEQHEELRKEFERKLEIKRNKIIQG
DDLAPGVLKVVKVYLAVRRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGL
AAKGIGDQINAMIKQQQSVAKLREYIQKAYDLGHGSQSVDLSTFTDEEVMRLAENLRKGLPLATPVFDGAHESEIKGLLE
LGGLPTSGQITLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA
YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGTHQMEPGMPESFNVLLKEIRALGIDMELDEE
>Mature_1341_residues
AYSYSEKKRIRKSFGKRPQVLNVPYLLTIQLDSYEKFIQRDSDGQQGLEAAFRSVFPIVSNNGSTELQYVSYELGEPVFD
VRECQIRGTTYAAPLRVKLRLVTFDREAAAGTVKDIKEQNVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDK
GKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYARIDRRRKLPATIILRALGYTTEEILSMFFDKVNFEIQDNKLLMTL
VPERLRGETAAFDIEANGKVYVERGRRITARHIRTLEKDGITQIEVPVEYIVGKVAAKDYVDLSTGEVVCPANMEISMEM
LAKLSQAGYKEIEVLFTNDLDHGPYISETLRVDPTYDRLSALVEIYRMMRPGEPPTKEAAEALFDNMFFSADRYDLSAVG
RMKFNRSLNLEEGVGSGILSNDDITGVMKKLIEIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVRERLSL
GDLDGITPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHTTHYGRLCPI
ETPEGPNIGLINSLSVYARTNNYGFLETPFRKVVNGQVTEDIEYLSAIEEGNYVIAQANSNLDENFRFTDTYVTCRGEHG
ESGLYKPEDIHYMDISTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAIVAKR
GGIVQRVDASRIVVKVNEDETIPGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGEPVARGEILADGPSTDLGELALGQNI
RVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGG
DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLKEAKKDL
TEELEILEAGLFTRVRNLLIEGGVSEAELDKVAREKWLEQTLDDEAKQNQLEQLAEQHEELRKEFERKLEIKRNKIIQGD
DLAPGVLKVVKVYLAVRRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLA
AKGIGDQINAMIKQQQSVAKLREYIQKAYDLGHGSQSVDLSTFTDEEVMRLAENLRKGLPLATPVFDGAHESEIKGLLEL
GGLPTSGQITLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAY
GAAYTLQEMLTVKSDDVNGRTKMYKNIVDGTHQMEPGMPESFNVLLKEIRALGIDMELDEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI33469941, Length=262, Percent_Identity=32.0610687022901, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI212286172, Length=262, Percent_Identity=32.0610687022901, Blast_Score=120, Evalue=8e-27,
Organism=Homo sapiens, GI4505941, Length=303, Percent_Identity=28.3828382838284, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI238908505, Length=159, Percent_Identity=32.7044025157233, Blast_Score=76, Evalue=3e-13,
Organism=Homo sapiens, GI238908503, Length=159, Percent_Identity=32.7044025157233, Blast_Score=76, Evalue=3e-13,
Organism=Escherichia coli, GI1790419, Length=1343, Percent_Identity=84.8845867460908, Blast_Score=2371, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506623, Length=233, Percent_Identity=31.7596566523605, Blast_Score=112, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI25144348, Length=301, Percent_Identity=28.2392026578073, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17552304, Length=248, Percent_Identity=31.0483870967742, Blast_Score=108, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324725, Length=249, Percent_Identity=31.3253012048193, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6325267, Length=249, Percent_Identity=31.3253012048193, Blast_Score=112, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=247, Percent_Identity=31.5789473684211, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136446, Length=261, Percent_Identity=32.5670498084291, Blast_Score=112, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136444, Length=248, Percent_Identity=28.2258064516129, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17647877, Length=110, Percent_Identity=39.0909090909091, Blast_Score=81, Evalue=7e-15,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_ACTP2 (A3N325)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054416.1
- ProteinModelPortal:   A3N325
- STRING:   A3N325
- GeneID:   4848804
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1727
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   A3N325
- ProtClustDB:   PRK00405
- BioCyc:   APLE416269:APL_1727-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 149712; Mature: 149581

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSYSEKKRIRKSFGKRPQVLNVPYLLTIQLDSYEKFIQRDSDGQQGLEAAFRSVFPIV
CCCCHHHHHHHHHHHCCCCCEECCCEEEEEEECHHHHHHHCCCCCHHHHHHHHHHHCCEE
SNNGSTELQYVSYELGEPVFDVRECQIRGTTYAAPLRVKLRLVTFDREAAAGTVKDIKEQ
ECCCCCEEEEEEHHHCCCCCCCHHEEECCCEEECCEEEEEEEEEECCHHHCCHHHHHHHC
NVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYR
CEEEECEEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDNLYARIDRRRKLPATIILRALGYTTEEILSMFFDKVNFEIQDNKLLMT
CCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCEEECCCEEEEE
LVPERLRGETAAFDIEANGKVYVERGRRITARHIRTLEKDGITQIEVPVEYIVGKVAAKD
ECCHHHCCCCEEEEEECCCEEEEECCCEEHHHHHHHHHHCCCEEEECCHHHHHHHHHHHC
YVDLSTGEVVCPANMEISMEMLAKLSQAGYKEIEVLFTNDLDHGPYISETLRVDPTYDRL
CEECCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEECCCCHHHH
SALVEIYRMMRPGEPPTKEAAEALFDNMFFSADRYDLSAVGRMKFNRSLNLEEGVGSGIL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
SNDDITGVMKKLIEIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVRERLS
CCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHCC
LGDLDGITPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTR
CCCCCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
ERAGFEVRDVHTTHYGRLCPIETPEGPNIGLINSLSVYARTNNYGFLETPFRKVVNGQVT
HHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECEEEEEEECCCCCCCCHHHHHHCCCHH
EDIEYLSAIEEGNYVIAQANSNLDENFRFTDTYVTCRGEHGESGLYKPEDIHYMDISTQQ
HHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEECCHHH
VVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAIVAK
HHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCEEEEEE
RGGIVQRVDASRIVVKVNEDETIPGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGEPVAR
CCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCC
GEILADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCV
CEEEECCCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHH
ARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEE
HHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLKEAKKD
HHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LTEELEILEAGLFTRVRNLLIEGGVSEAELDKVAREKWLEQTLDDEAKQNQLEQLAEQHE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRKEFERKLEIKRNKIIQGDDLAPGVLKVVKVYLAVRRQIQPGDKMAGRHGNKGVISKI
HHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
NPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMIKQQQSVA
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHH
KLREYIQKAYDLGHGSQSVDLSTFTDEEVMRLAENLRKGLPLATPVFDGAHESEIKGLLE
HHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGGLPTSGQITLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLG
HCCCCCCCEEEEEECCCCCHHCCCEEHHHHEEHHHHHHHCCHHHHCCCCCEEEEECCCCC
GKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGTHQMEPGMP
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCC
ESFNVLLKEIRALGIDMELDEE
HHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
AYSYSEKKRIRKSFGKRPQVLNVPYLLTIQLDSYEKFIQRDSDGQQGLEAAFRSVFPIV
CCCHHHHHHHHHHHCCCCCEECCCEEEEEEECHHHHHHHCCCCCHHHHHHHHHHHCCEE
SNNGSTELQYVSYELGEPVFDVRECQIRGTTYAAPLRVKLRLVTFDREAAAGTVKDIKEQ
ECCCCCEEEEEEHHHCCCCCCCHHEEECCCEEECCEEEEEEEEEECCHHHCCHHHHHHHC
NVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYR
CEEEECEEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDNLYARIDRRRKLPATIILRALGYTTEEILSMFFDKVNFEIQDNKLLMT
CCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCEEECCCEEEEE
LVPERLRGETAAFDIEANGKVYVERGRRITARHIRTLEKDGITQIEVPVEYIVGKVAAKD
ECCHHHCCCCEEEEEECCCEEEEECCCEEHHHHHHHHHHCCCEEEECCHHHHHHHHHHHC
YVDLSTGEVVCPANMEISMEMLAKLSQAGYKEIEVLFTNDLDHGPYISETLRVDPTYDRL
CEECCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEECCCCHHHH
SALVEIYRMMRPGEPPTKEAAEALFDNMFFSADRYDLSAVGRMKFNRSLNLEEGVGSGIL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
SNDDITGVMKKLIEIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVRERLS
CCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHCC
LGDLDGITPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTR
CCCCCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCH
ERAGFEVRDVHTTHYGRLCPIETPEGPNIGLINSLSVYARTNNYGFLETPFRKVVNGQVT
HHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECEEEEEEECCCCCCCCHHHHHHCCCHH
EDIEYLSAIEEGNYVIAQANSNLDENFRFTDTYVTCRGEHGESGLYKPEDIHYMDISTQQ
HHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEECCHHH
VVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAIVAK
HHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCCEEECCCEEEEEE
RGGIVQRVDASRIVVKVNEDETIPGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGEPVAR
CCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCC
GEILADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCV
CEEEECCCCCCHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHH
ARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEE
HHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLKEAKKD
HHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LTEELEILEAGLFTRVRNLLIEGGVSEAELDKVAREKWLEQTLDDEAKQNQLEQLAEQHE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRKEFERKLEIKRNKIIQGDDLAPGVLKVVKVYLAVRRQIQPGDKMAGRHGNKGVISKI
HHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCC
NPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMIKQQQSVA
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHH
KLREYIQKAYDLGHGSQSVDLSTFTDEEVMRLAENLRKGLPLATPVFDGAHESEIKGLLE
HHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGGLPTSGQITLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLG
HCCCCCCCEEEEEECCCCCHHCCCEEHHHHEEHHHHHHHCCHHHHCCCCCEEEEECCCCC
GKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGTHQMEPGMP
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCC
ESFNVLLKEIRALGIDMELDEE
HHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA