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The map label for this gene is rpoC [H]

Identifier: 126209192

GI number: 126209192

Start: 1961382

End: 1965620

Strand: Direct

Name: rpoC [H]

Synonym: APL_1728

Alternate gene names: 126209192

Gene position: 1961382-1965620 (Clockwise)

Preceding gene: 126209191

Following gene: 126209193

Centisome position: 86.23

GC content: 44.11

Gene sequence:

>4239_bases
GTGAAAGACTTAGTAAAGTTTTTAAAAGCACAATCAAAATCGAATGATGATTTTGATGTAATTAAAATTGGTTTAGCATC
ACCGGATAAAATCCGTTCTTGGTCTTTCGGTGAAGTAAAAAAACCGGAAACAATTAACTATCGTACCTTTAAACCTGAGC
GTGACGGTCTTTTCTGTGCACGTATCTTCGGACCGGTAAAAGATTACGAATGTTTATGCGGTAAATATAAACGTTTAAGA
CACCGCGGCGTAATCTGCGAAAAATGTGGTGTTGAAGTTACTCAAACTAAAGTACGTCGTGACCGTATGGGTCATATTGA
ACTTGCTTGTCCGGTGGCACACATTTGGTTCTTAAAATCACTTCCGTCCCGTATCGGTTTAATTTTAGATATGCCGTTAC
GCGATATTGAACGTGTACTTTACTTCGAATCTTATGTGGTTACCGAACCGGGAATGACCGATTTAGAAAAAAATCAGTTA
TTAACCGAAGAACAGTTCTTAGACGCAGAAGAGCGTTGGGGCGATGAGTTTGAAGCGAAAATGGGTGCGGAAGGTATTCA
AGCACTTTTACGCGATATGGACTTAGAGCACCAATGTGAAATGATGCGTGAAGAGTTACAAGAAACGAACTCTGAAACAA
AACGTAAGAAAATCACAAAACGCTTAAAATTATTAGAAGCATTCCAACAATCCGGTAACAAACCGGAGTGGATGGTAATG
ACCGTATTACCGGTACTTCCGCCGGATCTTCGTCCGTTAGTACCACTTGACGGCGGTCGTTTTGCGACTTCGGATCTGAA
CGATTTATATCGTCGTGTGATCAACCGTAACAACCGTTTAAAACGCTTATTAGATTTAGTAGCGCCGGATATCATCGTAC
GTAATGAAAAACGTATGTTACAAGAGTCTGTTGATGCGTTATTAGATAACGGTCGTCGTGGTCGTGCGATTACAGGTTCT
AACAAACGTCCGTTAAAATCTCTTGCAGATATGATCAAGGGTAAACAAGGTCGTTTCCGTCAGAACTTATTAGGTAAACG
TGTGGACTATTCAGGTCGTTCGGTAATCACCGTAGGTCCTTACTTACACCTACACCAATGTGGTTTGCCGAAAAAAATGG
CATTGGAATTATTCCGTCCGTTTATTTACTCTAAATTAGAATCTCGCGGCATTGCTTCAACAATCAAAGCTGCGAAGAAA
ATGGTTGAACGTGAAGAACCGATCGTATGGGATATCCTTGCGGAAGTGATTCGTGAACACCCAATTTTATTAAACCGTGC
GCCGACACTTCACCGTTTAGGTATCCAAGCGTTTGAGCCAATCTTAATCGAAGGTAAAGCAATCCAGTTACACCCGCTTG
TTTGTGCGGCGTTCAATGCGGACTTCGATGGTGACCAAATGGCGGTACACGTACCATTAACACTTGAAGCTCAGTTAGAA
GCTCGTGCGTTAATGATGTCAACTAACAATGTACTTTCACCGGCAAGTGGTGACCCGATTATCGTACCTTCTCAGGACGT
TGTATTAGGTCTTTACTATATGACGCGTGAGAAAGTGAATGCGAAAGGTGAAGGAATGTATTTCCTTGACCCACGTGAAG
CGGAAAAAGCATACCGTACCGGTCAAGCTGAATTACACGCTCGCGTAAAAGTTCGTATTACCGAACACGTGAAAAACGAA
GCGGGCGAATTAGTTGCGGAAACTAAGTTGTTAGATACTACTATCGGTCGTGCAATCTTATGGATGATCGCACCGAAAGG
TATGCCGTTTAAAGTATTCAACCAAACGTTAGGTAAAAAAGCGATTTCAAAATTAATCAACGAATCGTACCGTCGTTTAG
GTTTAAAAGAATCGGTAATCCTTGCCGACCAAATTATGTATACCGGTTTCGCGTACGCTGCTCGTTCAGGTGCGTCAGTC
GGTATCGACGATATGGTGATTCCGGCACAAAAACACGAAATTATTCGTGCGGCGGAAGCAGAAGTGGCAGAGATTCAAGA
ACAATTTAACTCAGGTCTTGTAACTGCGGGCGAACGTTATAACAAAGTAATCGATATTTGGGCGGCTGCAAACGAACGTG
TTGCAAAAGCAATGATGGAAAACCTTTCAACGGAAGAAGTCATCAACCGTGAAGGTAATCCGGAAAAACAAGCGTCATTC
AACAGTATCTTTATGATGGCTGACTCGGGTGCGCGTGGTTCTGCAGCTCAGATTCGTCAGTTAGCGGGTATGCGTGGTCT
TATGGCTCGTCCGGACGGCTCGATCATCGAAACACCGATTACCGCGAACTTCCGTGAAGGTCTGAACGTTCTTCAGTACT
TTATTTCAACCCACGGTGCGCGTAAAGGTCTTGCGGATACTGCATTAAAGACAGCGAACTCAGGTTACTTAACACGTCGT
TTAGTAGACGTAGCACAAGACTTAGTAATCACTGAAGATGACTGTGGTACGCACGAAGGTATCGTGATGACGCCGTTAAT
CGAAGGTGGTGATGTTAAAGAAGCATTACGTGATCGCGTATTAGGTCGTGTGGTGGCAGAAGACGTATTAAAACCGGGTA
CGGAAGAAGTATTAATTCCACGTAACACCTTAATCGATGAGAAATGGTGTGATGTGATTGATGCGGAATCTGTGGACGTA
ATCAAAGTACGTTCGGTGGTAACTTGTAACACAGACTTCGGTGTGTGTGCGAAATGTTACGGTCGTGACCTTGCTCGCGG
TCACCTTATCAACCAAGGTGAAGCAGTGGGTGTTATCGCAGCGCAATCAATCGGTGAACCGGGTACACAGCTAACCATGC
GTACGTTCCACATCGGTGGTGCGGCTTCTGCGGCAGCAAAAGAATCTAGCATCCAAGTGAAAAACGCAGGTACGATTAAA
TTAACTAACGCTAAATTTGTAACCAACAAAGAAGGCAAAATCGTATTAACTTCACGTAACACAGAATTAACCGTTATCGA
CACATTCGGTCGTACCAAAGAAAACTATAAAGTACCTTACGGTGCAGTGCTTTCTAAAAACGACGGTGCAGAAGTTGCAG
TAGGTGAAGTCGTTGCGAACTGGGATCCGCATACAATGCCGGTCATCTCAGAGGTAAGCGGTCGTATCCAATTCAGCGAC
ATCGTAGATGGCTTAACCGTTACTCGTCAAACTGACGAATTAACCGGTTTATCCTCTATCGTGGTGCAAGATGTGGGTGA
ACGTGCAACAGCAGGTAAAGATTTACGTCCGGCATTACGTTTAGTTGATGCACAAGGTAACGATATCTTAATTCCAAGCA
CAGACGTTGCAGCACAATACTTCTTACCGGGTAAAGCAATCGTAACTTTAGATGATGGTGCGGAAATCGAAGTCGGTGAA
GCATTAGCACGTATTCCGCAAGAATCTGTGGGTACGAAAGATATTACCGGTGGTCTTCCACGCGTAGCAGACTTATTCGA
AGCACGTAAACCGAAAGAGCCGGCAATCCTTGCTGAAATTTCAGGTATCGTGTCATTCGGTAAAGAGACTAAAGGTAAAC
GTCGTTTAGTGATCACACCGGCAGAAGGCGAAGCATTCGAAGAAATGATTCCAAAATGGCGTCAGCTCAACGTATTTGAA
GGCGAGATGGTACAACGTGGTGACGTAATCTCTGATGGTGCGGAAACGCCGCACGATATCTTACGTTTACGTGGCGTTCA
CGCTGTAACGGATTACATCGTAAATGAAGTACAAGAAGTTTACCGCTTACAAGGGGTAAAAATTAACGATAAACACATCG
AAGTTATCGTTCGCCAAATGTTACGTAAAGCGGTTATCACTAACGCATACGACAGCGAATTCCTCGAAGGGGAACAAGTT
GAAGTTTCACGTGTGAAAATTGCTAACCGTAAACGTGCAGAAGAAGGTAAACCGCTTGTTGAGTTCGAACGTGAATTACT
TGGTATTACCAAAGCGTCGCTTGCAACCGAGTCATTTATCTCAGCAGCGTCGTTCCAAGAAACCACACGTGTTCTTACTG
AAGCGGCAGTGGCAGGTAAACGTGACGAATTACGCGGCTTGAAAGAGAACGTAATCGTAGGTCGTTTAATCCCTGCGGGT
ACCGGTTTCGCATATCATCAAAATCGTGCGAAAAAACGTAACCAGCAAGAACAAGCGGTCGCTTTTGAAGCACCGGTTGA
AAAGCTAACGGGTTCGCAACCGATGCTGATATCGAAGCGGAATTCGAATTCGTTGCAGACGATGCAACTCAAAGCCTAG

Upstream 100 bases:

>100_bases
TGGTAAAAATTTTGCAAAATTTGACCGTTTGTAAAATAGATTTCCTCGTTTAGAGCCTTGTGTTCTAAGCAAAACTTTAA
TTCCTCACTAGGGGCAAAAA

Downstream 100 bases:

>100_bases
CAGCGTTATTAAATGCGGGTGATGAAGAGTAATTCTTAGTATCGATAGAGAAAAGTAAAGCCTCCAGAACGAAAGTTCTG
GGGGCTTTTTGTTAGGAATA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1412; Mature: 1412

Protein sequence:

>1412_residues
MKDLVKFLKAQSKSNDDFDVIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLR
HRGVICEKCGVEVTQTKVRRDRMGHIELACPVAHIWFLKSLPSRIGLILDMPLRDIERVLYFESYVVTEPGMTDLEKNQL
LTEEQFLDAEERWGDEFEAKMGAEGIQALLRDMDLEHQCEMMREELQETNSETKRKKITKRLKLLEAFQQSGNKPEWMVM
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRMLQESVDALLDNGRRGRAITGS
NKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYSKLESRGIASTIKAAKK
MVEREEPIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
ARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTREKVNAKGEGMYFLDPREAEKAYRTGQAELHARVKVRITEHVKNE
AGELVAETKLLDTTIGRAILWMIAPKGMPFKVFNQTLGKKAISKLINESYRRLGLKESVILADQIMYTGFAYAARSGASV
GIDDMVIPAQKHEIIRAAEAEVAEIQEQFNSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGNPEKQASF
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRR
LVDVAQDLVITEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIPRNTLIDEKWCDVIDAESVDV
IKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNAGTIK
LTNAKFVTNKEGKIVLTSRNTELTVIDTFGRTKENYKVPYGAVLSKNDGAEVAVGEVVANWDPHTMPVISEVSGRIQFSD
IVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPALRLVDAQGNDILIPSTDVAAQYFLPGKAIVTLDDGAEIEVGE
ALARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLVITPAEGEAFEEMIPKWRQLNVFE
GEMVQRGDVISDGAETPHDILRLRGVHAVTDYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKAVITNAYDSEFLEGEQV
EVSRVKIANRKRAEEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGFAYHQNRAKKRNQQEQAVAFEAPVEKLTGSQPMLISKRNSNSLQTMQLKA

Sequences:

>Translated_1412_residues
MKDLVKFLKAQSKSNDDFDVIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLR
HRGVICEKCGVEVTQTKVRRDRMGHIELACPVAHIWFLKSLPSRIGLILDMPLRDIERVLYFESYVVTEPGMTDLEKNQL
LTEEQFLDAEERWGDEFEAKMGAEGIQALLRDMDLEHQCEMMREELQETNSETKRKKITKRLKLLEAFQQSGNKPEWMVM
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRMLQESVDALLDNGRRGRAITGS
NKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYSKLESRGIASTIKAAKK
MVEREEPIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
ARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTREKVNAKGEGMYFLDPREAEKAYRTGQAELHARVKVRITEHVKNE
AGELVAETKLLDTTIGRAILWMIAPKGMPFKVFNQTLGKKAISKLINESYRRLGLKESVILADQIMYTGFAYAARSGASV
GIDDMVIPAQKHEIIRAAEAEVAEIQEQFNSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGNPEKQASF
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRR
LVDVAQDLVITEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIPRNTLIDEKWCDVIDAESVDV
IKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNAGTIK
LTNAKFVTNKEGKIVLTSRNTELTVIDTFGRTKENYKVPYGAVLSKNDGAEVAVGEVVANWDPHTMPVISEVSGRIQFSD
IVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPALRLVDAQGNDILIPSTDVAAQYFLPGKAIVTLDDGAEIEVGE
ALARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLVITPAEGEAFEEMIPKWRQLNVFE
GEMVQRGDVISDGAETPHDILRLRGVHAVTDYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKAVITNAYDSEFLEGEQV
EVSRVKIANRKRAEEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGFAYHQNRAKKRNQQEQAVAFEAPVEKLTGSQPMLISKRNSNSLQTMQLKA
>Mature_1412_residues
MKDLVKFLKAQSKSNDDFDVIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLR
HRGVICEKCGVEVTQTKVRRDRMGHIELACPVAHIWFLKSLPSRIGLILDMPLRDIERVLYFESYVVTEPGMTDLEKNQL
LTEEQFLDAEERWGDEFEAKMGAEGIQALLRDMDLEHQCEMMREELQETNSETKRKKITKRLKLLEAFQQSGNKPEWMVM
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRMLQESVDALLDNGRRGRAITGS
NKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYSKLESRGIASTIKAAKK
MVEREEPIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
ARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTREKVNAKGEGMYFLDPREAEKAYRTGQAELHARVKVRITEHVKNE
AGELVAETKLLDTTIGRAILWMIAPKGMPFKVFNQTLGKKAISKLINESYRRLGLKESVILADQIMYTGFAYAARSGASV
GIDDMVIPAQKHEIIRAAEAEVAEIQEQFNSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGNPEKQASF
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRR
LVDVAQDLVITEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIPRNTLIDEKWCDVIDAESVDV
IKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNAGTIK
LTNAKFVTNKEGKIVLTSRNTELTVIDTFGRTKENYKVPYGAVLSKNDGAEVAVGEVVANWDPHTMPVISEVSGRIQFSD
IVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPALRLVDAQGNDILIPSTDVAAQYFLPGKAIVTLDDGAEIEVGE
ALARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLVITPAEGEAFEEMIPKWRQLNVFE
GEMVQRGDVISDGAETPHDILRLRGVHAVTDYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKAVITNAYDSEFLEGEQV
EVSRVKIANRKRAEEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGFAYHQNRAKKRNQQEQAVAFEAPVEKLTGSQPMLISKRNSNSLQTMQLKA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=918, Percent_Identity=25.9259259259259, Blast_Score=198, Evalue=4e-50,
Organism=Homo sapiens, GI39725938, Length=855, Percent_Identity=25.6140350877193, Blast_Score=183, Evalue=1e-45,
Organism=Homo sapiens, GI103471997, Length=604, Percent_Identity=25.6622516556291, Blast_Score=122, Evalue=2e-27,
Organism=Escherichia coli, GI2367335, Length=1399, Percent_Identity=82.7734095782702, Blast_Score=2399, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=903, Percent_Identity=26.0243632336656, Blast_Score=189, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25145495, Length=707, Percent_Identity=27.1570014144272, Blast_Score=179, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6324690, Length=607, Percent_Identity=26.0296540362438, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6320061, Length=883, Percent_Identity=23.1030577576444, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17530899, Length=915, Percent_Identity=24.5901639344262, Blast_Score=180, Evalue=6e-45,
Organism=Drosophila melanogaster, GI281360912, Length=502, Percent_Identity=26.0956175298805, Blast_Score=132, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 156765; Mature: 156765

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00381 CLP_PROTEASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLVKFLKAQSKSNDDFDVIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCA
CHHHHHHHHHHCCCCCCCEEEEEECCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPVKDYECLCGKYKRLRHRGVICEKCGVEVTQTKVRRDRMGHIELACPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
LPSRIGLILDMPLRDIERVLYFESYVVTEPGMTDLEKNQLLTEEQFLDAEERWGDEFEAK
HHHHCCEEEECCHHHHHHHHHHHHEEEECCCCCCCHHHHCCCHHHHCCCHHHCCCHHHHH
MGAEGIQALLRDMDLEHQCEMMREELQETNSETKRKKITKRLKLLEAFQQSGNKPEWMVM
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCHHHHH
QESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGP
HHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
YLHLHQCGLPKKMALELFRPFIYSKLESRGIASTIKAAKKMVEREEPIVWDILAEVIREH
EEEEHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
CEEEECCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHH
ARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTREKVNAKGEGMYFLDPREAEKAYRT
HHHHEEECCCCCCCCCCCEEEECCCHHHEEHHHHHHHHCCCCCCCEEEECCHHHHHHHHC
GQAELHARVKVRITEHVKNEAGELVAETKLLDTTIGRAILWMIAPKGMPFKVFNQTLGKK
CCHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHH
AISKLINESYRRLGLKESVILADQIMYTGFAYAARSGASVGIDDMVIPAQKHEIIRAAEA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHH
EVAEIQEQFNSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGNPEKQASF
HHHHHHHHHCCCCEECCHHHCCEEEEEHHCHHHHHHHHHHCCCHHHHHCCCCCCHHHCCC
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGA
CEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCC
RKGLADTALKTANSGYLTRRLVDVAQDLVITEDDCGTHEGIVMTPLIEGGDVKEALRDRV
CCCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCCHHHHHHHHH
LGRVVAEDVLKPGTEEVLIPRNTLIDEKWCDVIDAESVDVIKVRSVVTCNTDFGVCAKCY
HHHHHHHHHHCCCCCCEEECCHHHCCHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHH
GRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNAGTIK
CCHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHCCCCCEEEECCCEEE
LTNAKFVTNKEGKIVLTSRNTELTVIDTFGRTKENYKVPYGAVLSKNDGAEVAVGEVVAN
EECCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEHHHEEC
WDPHTMPVISEVSGRIQFSDIVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPALR
CCCCCCHHHHHHCCCEEEHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHCCCCCCCHHHH
LVDAQGNDILIPSTDVAAQYFLPGKAIVTLDDGAEIEVGEALARIPQESVGTKDITGGLP
HEECCCCEEEECCCHHHHHEECCCCEEEEECCCCCEEHHHHHHHCCHHHCCCCCCCCCCH
RVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLVITPAEGEAFEEMIPKWRQLNVFE
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCCHHHCCCCCC
GEMVQRGDVISDGAETPHDILRLRGVHAVTDYIVNEVQEVYRLQGVKINDKHIEVIVRQM
CCHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKAVITNAYDSEFLEGEQVEVSRVKIANRKRAEEGKPLVEFERELLGITKASLATESFI
HHHHHHCCCCCHHHCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRAKKRNQQEQAV
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHHHHHHCCHHHHHH
AFEAPVEKLTGSQPMLISKRNSNSLQTMQLKA
HHHCCHHHHCCCCCEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MKDLVKFLKAQSKSNDDFDVIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCA
CHHHHHHHHHHCCCCCCCEEEEEECCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPVKDYECLCGKYKRLRHRGVICEKCGVEVTQTKVRRDRMGHIELACPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
LPSRIGLILDMPLRDIERVLYFESYVVTEPGMTDLEKNQLLTEEQFLDAEERWGDEFEAK
HHHHCCEEEECCHHHHHHHHHHHHEEEECCCCCCCHHHHCCCHHHHCCCHHHCCCHHHHH
MGAEGIQALLRDMDLEHQCEMMREELQETNSETKRKKITKRLKLLEAFQQSGNKPEWMVM
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEECCHHHHH
QESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGP
HHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
YLHLHQCGLPKKMALELFRPFIYSKLESRGIASTIKAAKKMVEREEPIVWDILAEVIREH
EEEEHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLE
CEEEECCCCHHHHCHHHCCCEEEECCEEEECCEEEEEECCCCCCCCEEEEEEEEEECCHH
ARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTREKVNAKGEGMYFLDPREAEKAYRT
HHHHEEECCCCCCCCCCCEEEECCCHHHEEHHHHHHHHCCCCCCCEEEECCHHHHHHHHC
GQAELHARVKVRITEHVKNEAGELVAETKLLDTTIGRAILWMIAPKGMPFKVFNQTLGKK
CCHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHH
AISKLINESYRRLGLKESVILADQIMYTGFAYAARSGASVGIDDMVIPAQKHEIIRAAEA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHH
EVAEIQEQFNSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGNPEKQASF
HHHHHHHHHCCCCEECCHHHCCEEEEEHHCHHHHHHHHHHCCCHHHHHCCCCCCHHHCCC
NSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGA
CEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCC
RKGLADTALKTANSGYLTRRLVDVAQDLVITEDDCGTHEGIVMTPLIEGGDVKEALRDRV
CCCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCCHHHHHHHHH
LGRVVAEDVLKPGTEEVLIPRNTLIDEKWCDVIDAESVDVIKVRSVVTCNTDFGVCAKCY
HHHHHHHHHHCCCCCCEEECCHHHCCHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHH
GRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNAGTIK
CCHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHCCCCCEEEECCCEEE
LTNAKFVTNKEGKIVLTSRNTELTVIDTFGRTKENYKVPYGAVLSKNDGAEVAVGEVVAN
EECCEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEHHHEEC
WDPHTMPVISEVSGRIQFSDIVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPALR
CCCCCCHHHHHHCCCEEEHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHCCCCCCCHHHH
LVDAQGNDILIPSTDVAAQYFLPGKAIVTLDDGAEIEVGEALARIPQESVGTKDITGGLP
HEECCCCEEEECCCHHHHHEECCCCEEEEECCCCCEEHHHHHHHCCHHHCCCCCCCCCCH
RVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLVITPAEGEAFEEMIPKWRQLNVFE
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCCHHHCCCCCC
GEMVQRGDVISDGAETPHDILRLRGVHAVTDYIVNEVQEVYRLQGVKINDKHIEVIVRQM
CCHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKAVITNAYDSEFLEGEQVEVSRVKIANRKRAEEGKPLVEFERELLGITKASLATESFI
HHHHHHCCCCCHHHCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQNRAKKRNQQEQAV
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHHHHHHCCHHHHHH
AFEAPVEKLTGSQPMLISKRNSNSLQTMQLKA
HHHCCHHHHCCCCCEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA