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The map label for this gene is srlR [H]

Identifier: 126209096

GI number: 126209096

Start: 1857436

End: 1858194

Strand: Reverse

Name: srlR [H]

Synonym: APL_1632

Alternate gene names: 126209096

Gene position: 1858194-1857436 (Counterclockwise)

Preceding gene: 126209097

Following gene: 126209095

Centisome position: 81.7

GC content: 41.9

Gene sequence:

>759_bases
ATGTCAAAGAGAAACACACAACAACGCCGCCATTTAATCGTAAAGATGGTTCAAGAGGAAGGTGAAGTTAGCGTAGATAC
GTTAGCTCATTTTTTTGAAACCTCGGAAGTCACGATTCGTAAGGATTTAACCGCTTTAGAAGAAAGCGGTTTCTTATTGC
GTCGTTATGGCGGAGCGGTAAAAATTCCGTTGGAAATGATAGATGATTCGAACGAGAAACTTTCGAAACAAAAGTTAGCG
ATTGCTAATGAGGCGGTAAAACAAATTCGTGATCATAATCGAATTATTATCGATAGCGGCAGTACGACGGGTGCAATGGT
CAAAATGCTCTACCAAACCGGTTTAGTGGTGATGACCAATTCTCTGTCTTTAGCGACCGAGCTGACTTTATTAGACAATG
AACCTACCGTATTGATGACCGGCGGTACTTGGGATAGCCGTTCCGATTCGTTTCAAGGAAAAGTCGCCGAGCAAGTGTTA
TGCTCGTACGATTTTGACCAATTGTTTATCGGGGCGGATAGTTTGGATTTAGAACGGGGAACGACGACTTTTAATGAGTT
GGTCGGCTTAAGCCAAGTGATGGCGAAAGTTTCTCGTGAAGTGATTGTATTGATCGAATCACAAAAATTCGGAAGAAAAA
TGCCGAATTTAGAGTTGGAATGGGCTGCAATCCATAAATTAATTACAGACTCGGAAATTACCGAAGAAGTAAAAGCGGCG
ATTGAAAAGCATGGCGTTCAAGTCATTATTGCCCAATAG

Upstream 100 bases:

>100_bases
TTTATTAAATTTATTGCATAAATAAATTAGACTAAATATAATAAAAAAGTTTTGAAGCGAAATTTTTTGAGTTTGGTTCG
AAACTTTTTGTGGAAATAGA

Downstream 100 bases:

>100_bases
TAAAACATAATGAGTATGCAAAACAGGGTAAATTTTTCTGAAAAAATAACCGCTTGTCACGCATTCTTATACTCAATCAG
TTATAACGGTTTTTAATTTA

Product: sugar metabolism transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSKRNTQQRRHLIVKMVQEEGEVSVDTLAHFFETSEVTIRKDLTALEESGFLLRRYGGAVKIPLEMIDDSNEKLSKQKLA
IANEAVKQIRDHNRIIIDSGSTTGAMVKMLYQTGLVVMTNSLSLATELTLLDNEPTVLMTGGTWDSRSDSFQGKVAEQVL
CSYDFDQLFIGADSLDLERGTTTFNELVGLSQVMAKVSREVIVLIESQKFGRKMPNLELEWAAIHKLITDSEITEEVKAA
IEKHGVQVIIAQ

Sequences:

>Translated_252_residues
MSKRNTQQRRHLIVKMVQEEGEVSVDTLAHFFETSEVTIRKDLTALEESGFLLRRYGGAVKIPLEMIDDSNEKLSKQKLA
IANEAVKQIRDHNRIIIDSGSTTGAMVKMLYQTGLVVMTNSLSLATELTLLDNEPTVLMTGGTWDSRSDSFQGKVAEQVL
CSYDFDQLFIGADSLDLERGTTTFNELVGLSQVMAKVSREVIVLIESQKFGRKMPNLELEWAAIHKLITDSEITEEVKAA
IEKHGVQVIIAQ
>Mature_251_residues
SKRNTQQRRHLIVKMVQEEGEVSVDTLAHFFETSEVTIRKDLTALEESGFLLRRYGGAVKIPLEMIDDSNEKLSKQKLAI
ANEAVKQIRDHNRIIIDSGSTTGAMVKMLYQTGLVVMTNSLSLATELTLLDNEPTVLMTGGTWDSRSDSFQGKVAEQVLC
SYDFDQLFIGADSLDLERGTTTFNELVGLSQVMAKVSREVIVLIESQKFGRKMPNLELEWAAIHKLITDSEITEEVKAAI
EKHGVQVIIAQ

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=43.1451612903226, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=35.8267716535433, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI226510968, Length=252, Percent_Identity=29.3650793650794, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=29.0836653386454, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789829, Length=248, Percent_Identity=26.2096774193548, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=30.4721030042918, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790753, Length=263, Percent_Identity=24.3346007604563, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=25.0996015936255, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082344, Length=257, Percent_Identity=24.124513618677, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28146; Mature: 28014

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRNTQQRRHLIVKMVQEEGEVSVDTLAHFFETSEVTIRKDLTALEESGFLLRRYGGAV
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHCCEEEECCCCEE
KIPLEMIDDSNEKLSKQKLAIANEAVKQIRDHNRIIIDSGSTTGAMVKMLYQTGLVVMTN
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCEEEEEC
SLSLATELTLLDNEPTVLMTGGTWDSRSDSFQGKVAEQVLCSYDFDQLFIGADSLDLERG
CCEEEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHEEECCCCCCCCCC
TTTFNELVGLSQVMAKVSREVIVLIESQKFGRKMPNLELEWAAIHKLITDSEITEEVKAA
CCHHHHHHHHHHHHHHHCCEEEEEEECHHHCCCCCCCEEHHHHHHHHHCCHHHHHHHHHH
IEKHGVQVIIAQ
HHHCCEEEEEEC
>Mature Secondary Structure 
SKRNTQQRRHLIVKMVQEEGEVSVDTLAHFFETSEVTIRKDLTALEESGFLLRRYGGAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHCCEEEECCCCEE
KIPLEMIDDSNEKLSKQKLAIANEAVKQIRDHNRIIIDSGSTTGAMVKMLYQTGLVVMTN
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCEEEEEC
SLSLATELTLLDNEPTVLMTGGTWDSRSDSFQGKVAEQVLCSYDFDQLFIGADSLDLERG
CCEEEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHEEECCCCCCCCCC
TTTFNELVGLSQVMAKVSREVIVLIESQKFGRKMPNLELEWAAIHKLITDSEITEEVKAA
CCHHHHHHHHHHHHHHHCCEEEEEEECHHHCCCCCCCEEHHHHHHHHHCCHHHHHHHHHH
IEKHGVQVIIAQ
HHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]