Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 126209095

GI number: 126209095

Start: 1855480

End: 1857312

Strand: Reverse

Name: glmS [H]

Synonym: APL_1631

Alternate gene names: 126209095

Gene position: 1857312-1855480 (Counterclockwise)

Preceding gene: 126209096

Following gene: 126209094

Centisome position: 81.66

GC content: 42.99

Gene sequence:

>1833_bases
ATGTGCGGAATTGTAGGTGCAGTAGCGCAACGTGATGTAGCAAAAATCTTAGTGGACGGTTTACATCGTTTGGAATATCG
TGGTTATGACTCTGCCGGTGTTGCGGTGTTAAATAACGAACACAATATGCAAATCGTACGTCGTGTCGGTAAAGTAAAAG
AACTTGACGACGCTTTAGCGGTAAAACCGCTTTTAGGCGGCACAGGTATTGCGCATACGCGTTGGGCAACTCACGGCGAG
CCTTCCGAGACTAATGCTCACCCGCATCGCAGCGGTAAAATCGCCGTGGTACATAACGGTATCATTGAGAACTACGAAGA
ATTAAAAGTGGTTTTACAAGAGCGCGGTTATGTATTCCAATCACAAACGGATACCGAAGTTATCGCTCACTTAGTTGAAT
GGGAATTACGTTCGGCTAAATCTTTATTAGAAGCGGTACAAAAAACCGTGGTTCAGCTTCGTGGTGCATACGGTACGGTA
GTAATGAATCAAGATGAACCGGAGCATTTAATCGTTGCTCGTTCAGGTTCTCCGTTAGTTATCGGTTACGGTATCGGTGA
GAATTTCTTAGCGTCAGACCCGTTGGCATTGTTAAGCGTAACACGCCGTTTCGCTTACCTTGAAGAAGGCGATGTAGCGG
AAATTACCCGTGAAACCGTTGATATTTATACGCGTGACGGTCAAAAAGTCGAACGTGAAATTCACGAAGGTAATTTTGAA
GCGGATGCGGCGGACAAAGGTCAATACCGTCACTATATGCAAAAAGAAATTTTCGAACAACCGGTTGCGATTATGAATAC
CTTAGACGGTCGTATCGAAAACGGTAAAGTGAAAATTGATGCGATTGGTCCGAATGTGGCGGAAATCTTATCTAAAGTTG
AACACGTGCAAATCGTTGCATGCGGTACTTCTTATAATGCAGGTATGGTTGCTCGTTATTGGTTTGAAGCAATTGCAGGT
GTGAGCTGTGACGTTGAAATTGCCTCTGAGTTCCGTTATCGTAAATTCGTAACACGTCCGAACAGCTTATTATTAACGCT
TTCACAATCAGGTGAGACGGCGGATACTTTAGCGGCATTACGCTTAGCGAAAGAATCGGGTTATATGTCTGCAATGACGA
TTTGTAATGTGGCAAGTTCTTCACTTGTACGTGAGTCTGATTTTGCTTTTATGACCAAAGCCGGCGTAGAAATCGGTGTG
GCATCGACAAAAGCATTTACAACGCAATTAACTTGTATGTTGTTATTAAATGTGGCGATCGGTCGCTTAAAAGGCACGGT
ATCCGAAGAGCAAGAACATCACATTATTCAATCGTTACAACGTTTACCGGCACAAATCGAAAGTGCGTTAGTATTCGATA
AACAAATTGAAAAATTATCGGAAGATTTTGCGGATAAACACCATACTTTATTCTTAGGTCGCGGCGAATACTATCCGATT
GCAATGGAATCCGCATTGAAATTAAAAGAAATTTCATACATTCACGCGGAAGCCTATGCGGCGGGCGAATTAAAACACGG
TCCGTTAGCGTTAATCGATAGCGAAATGCCGGTTGTAGTCGTTGCACCGGAAAACGATTTACTTGAAAAAGTGAAATCAA
ATATTGAAGAAGTACGTGCGCGCGGCGGTCAGTTATACGTATTTGCGGATCATGATGCCGGTTTTGCTGAAGCGGAAGGT
TTTAAAACGATTTTAATGCCTAAAGTTGATGAAGTAACCGCACCGATTTTCTATACCGTGCCGTTACAATTACTTTCATA
TCACATCGCTTTAATTAAAGGTACCGATGTGGATCAGCCTCGTAACTTAGCGAAAGCGGTAACCGTAGAATAA

Upstream 100 bases:

>100_bases
CAGGGTAAATTTTTCTGAAAAAATAACCGCTTGTCACGCATTCTTATACTCAATCAGTTATAACGGTTTTTAATTTAATC
TTAATATAGGAACAAAAAAT

Downstream 100 bases:

>100_bases
TTGTTAATTTTACTATCGAAAGCCTCCGAATATTCGGAGGCTTTTTTTATGTTTATCACTTTTGTAAAAAACAATAGAAA
TTTGACCGCTTGTTTAAAAA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MCGIVGAVAQRDVAKILVDGLHRLEYRGYDSAGVAVLNNEHNMQIVRRVGKVKELDDALAVKPLLGGTGIAHTRWATHGE
PSETNAHPHRSGKIAVVHNGIIENYEELKVVLQERGYVFQSQTDTEVIAHLVEWELRSAKSLLEAVQKTVVQLRGAYGTV
VMNQDEPEHLIVARSGSPLVIGYGIGENFLASDPLALLSVTRRFAYLEEGDVAEITRETVDIYTRDGQKVEREIHEGNFE
ADAADKGQYRHYMQKEIFEQPVAIMNTLDGRIENGKVKIDAIGPNVAEILSKVEHVQIVACGTSYNAGMVARYWFEAIAG
VSCDVEIASEFRYRKFVTRPNSLLLTLSQSGETADTLAALRLAKESGYMSAMTICNVASSSLVRESDFAFMTKAGVEIGV
ASTKAFTTQLTCMLLLNVAIGRLKGTVSEEQEHHIIQSLQRLPAQIESALVFDKQIEKLSEDFADKHHTLFLGRGEYYPI
AMESALKLKEISYIHAEAYAAGELKHGPLALIDSEMPVVVVAPENDLLEKVKSNIEEVRARGGQLYVFADHDAGFAEAEG
FKTILMPKVDEVTAPIFYTVPLQLLSYHIALIKGTDVDQPRNLAKAVTVE

Sequences:

>Translated_610_residues
MCGIVGAVAQRDVAKILVDGLHRLEYRGYDSAGVAVLNNEHNMQIVRRVGKVKELDDALAVKPLLGGTGIAHTRWATHGE
PSETNAHPHRSGKIAVVHNGIIENYEELKVVLQERGYVFQSQTDTEVIAHLVEWELRSAKSLLEAVQKTVVQLRGAYGTV
VMNQDEPEHLIVARSGSPLVIGYGIGENFLASDPLALLSVTRRFAYLEEGDVAEITRETVDIYTRDGQKVEREIHEGNFE
ADAADKGQYRHYMQKEIFEQPVAIMNTLDGRIENGKVKIDAIGPNVAEILSKVEHVQIVACGTSYNAGMVARYWFEAIAG
VSCDVEIASEFRYRKFVTRPNSLLLTLSQSGETADTLAALRLAKESGYMSAMTICNVASSSLVRESDFAFMTKAGVEIGV
ASTKAFTTQLTCMLLLNVAIGRLKGTVSEEQEHHIIQSLQRLPAQIESALVFDKQIEKLSEDFADKHHTLFLGRGEYYPI
AMESALKLKEISYIHAEAYAAGELKHGPLALIDSEMPVVVVAPENDLLEKVKSNIEEVRARGGQLYVFADHDAGFAEAEG
FKTILMPKVDEVTAPIFYTVPLQLLSYHIALIKGTDVDQPRNLAKAVTVE
>Mature_610_residues
MCGIVGAVAQRDVAKILVDGLHRLEYRGYDSAGVAVLNNEHNMQIVRRVGKVKELDDALAVKPLLGGTGIAHTRWATHGE
PSETNAHPHRSGKIAVVHNGIIENYEELKVVLQERGYVFQSQTDTEVIAHLVEWELRSAKSLLEAVQKTVVQLRGAYGTV
VMNQDEPEHLIVARSGSPLVIGYGIGENFLASDPLALLSVTRRFAYLEEGDVAEITRETVDIYTRDGQKVEREIHEGNFE
ADAADKGQYRHYMQKEIFEQPVAIMNTLDGRIENGKVKIDAIGPNVAEILSKVEHVQIVACGTSYNAGMVARYWFEAIAG
VSCDVEIASEFRYRKFVTRPNSLLLTLSQSGETADTLAALRLAKESGYMSAMTICNVASSSLVRESDFAFMTKAGVEIGV
ASTKAFTTQLTCMLLLNVAIGRLKGTVSEEQEHHIIQSLQRLPAQIESALVFDKQIEKLSEDFADKHHTLFLGRGEYYPI
AMESALKLKEISYIHAEAYAAGELKHGPLALIDSEMPVVVVAPENDLLEKVKSNIEEVRARGGQLYVFADHDAGFAEAEG
FKTILMPKVDEVTAPIFYTVPLQLLSYHIALIKGTDVDQPRNLAKAVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=35.4744525547445, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=36.4035087719298, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI29570798, Length=278, Percent_Identity=26.978417266187, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1790167, Length=610, Percent_Identity=69.5081967213115, Blast_Score=880, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=173, Percent_Identity=29.4797687861272, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17539970, Length=713, Percent_Identity=34.5021037868163, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17532897, Length=430, Percent_Identity=36.9767441860465, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17532899, Length=430, Percent_Identity=36.9767441860465, Blast_Score=270, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322745, Length=451, Percent_Identity=36.3636363636364, Blast_Score=266, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6323731, Length=429, Percent_Identity=29.6037296037296, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=36.2745098039216, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=35.5685131195335, Blast_Score=407, Evalue=1e-113,
Organism=Drosophila melanogaster, GI28573187, Length=267, Percent_Identity=27.7153558052434, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24659598, Length=271, Percent_Identity=26.5682656826568, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24659604, Length=247, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67202; Mature: 67202

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRDVAKILVDGLHRLEYRGYDSAGVAVLNNEHNMQIVRRVGKVKELDDALA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VKPLLGGTGIAHTRWATHGEPSETNAHPHRSGKIAVVHNGIIENYEELKVVLQERGYVFQ
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCHHHHHHHHHHCCCEEE
SQTDTEVIAHLVEWELRSAKSLLEAVQKTVVQLRGAYGTVVMNQDEPEHLIVARSGSPLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCEE
IGYGIGENFLASDPLALLSVTRRFAYLEEGDVAEITRETVDIYTRDGQKVEREIHEGNFE
EEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHCCCCC
ADAADKGQYRHYMQKEIFEQPVAIMNTLDGRIENGKVKIDAIGPNVAEILSKVEHVQIVA
CCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCEEEEEE
CGTSYNAGMVARYWFEAIAGVSCDVEIASEFRYRKFVTRPNSLLLTLSQSGETADTLAAL
ECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKESGYMSAMTICNVASSSLVRESDFAFMTKAGVEIGVASTKAFTTQLTCMLLLNVAI
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
GRLKGTVSEEQEHHIIQSLQRLPAQIESALVFDKQIEKLSEDFADKHHTLFLGRGEYYPI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
AMESALKLKEISYIHAEAYAAGELKHGPLALIDSEMPVVVVAPENDLLEKVKSNIEEVRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGQLYVFADHDAGFAEAEGFKTILMPKVDEVTAPIFYTVPLQLLSYHIALIKGTDVDQP
CCCEEEEEECCCCCCCCCCCCEEEECCCCHHHCCCEEEEHHHHHHHHEEEEEECCCCCCC
RNLAKAVTVE
HHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRDVAKILVDGLHRLEYRGYDSAGVAVLNNEHNMQIVRRVGKVKELDDALA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VKPLLGGTGIAHTRWATHGEPSETNAHPHRSGKIAVVHNGIIENYEELKVVLQERGYVFQ
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCHHHHHHHHHHCCCEEE
SQTDTEVIAHLVEWELRSAKSLLEAVQKTVVQLRGAYGTVVMNQDEPEHLIVARSGSPLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCEE
IGYGIGENFLASDPLALLSVTRRFAYLEEGDVAEITRETVDIYTRDGQKVEREIHEGNFE
EEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHCCCCC
ADAADKGQYRHYMQKEIFEQPVAIMNTLDGRIENGKVKIDAIGPNVAEILSKVEHVQIVA
CCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCEEEEEE
CGTSYNAGMVARYWFEAIAGVSCDVEIASEFRYRKFVTRPNSLLLTLSQSGETADTLAAL
ECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKESGYMSAMTICNVASSSLVRESDFAFMTKAGVEIGVASTKAFTTQLTCMLLLNVAI
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
GRLKGTVSEEQEHHIIQSLQRLPAQIESALVFDKQIEKLSEDFADKHHTLFLGRGEYYPI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
AMESALKLKEISYIHAEAYAAGELKHGPLALIDSEMPVVVVAPENDLLEKVKSNIEEVRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH
RGGQLYVFADHDAGFAEAEGFKTILMPKVDEVTAPIFYTVPLQLLSYHIALIKGTDVDQP
CCCEEEEEECCCCCCCCCCCCEEEECCCCHHHCCCEEEEHHHHHHHHEEEEEECCCCCCC
RNLAKAVTVE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA