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The map label for this gene is cpxD [H]

Identifier: 126209046

GI number: 126209046

Start: 1809226

End: 1810410

Strand: Direct

Name: cpxD [H]

Synonym: APL_1582

Alternate gene names: 126209046

Gene position: 1809226-1810410 (Clockwise)

Preceding gene: 126209038

Following gene: 126209047

Centisome position: 79.54

GC content: 44.05

Gene sequence:

>1185_bases
ATGAAACTCATCAAACTTAGATTACTCCTTTCTTTGGGGCTGGTTGCTAGTTTGGCTGCCTGCTCAAGCTTACCCACTTC
AGGCCCTAGCCATAGTGCGATTTTAGAGGCTAATTCCCAGAACTCAGATAAACCTTTACCGGAAGTTAATTTAGTGGAGT
TAGATAATGGCTTAGTTCAGCAGTTGTATCAGACTCAGCAAAGTCAGCAATTTTCCGGCTTTTTAGGCACGGCTGGCGGT
GCTGGATATGCCGGTGCGGTCAATGTGGGGGATGTTCTTGAAATTTCAATTTGGGAAGCGCCACCGGCAGTGTTGTTTGG
CGGTACTTTTAGTTCTGAAGGGCAAGGTAGCGGGCATTTAACGCAATTACCGGCGCAAATGGTTAACCAAAACGGTACGG
TTACTGTGCCGTTTGTGGGTAATATTCGTGTTGCAGGTAAAACACCGGAAGCGATTCAGTCTCAAATTGTTGGGGCATTG
CAACGTAAAGCGAATCAGCCACAAGTATTAGTAAAAATTGCGAATAATAACTCTGCGGATGTTACGGTTATTCGTCAGGG
TAACAGTATTCGTATGCCGCTGAGTGCGAATAACGAACGTGTGTTAGATGCTGTTGCAGCAGTAGGCGGTACAACTGAAA
ATATTGAAGACGTTACCGTAAAATTAACTCGTGGCTCGCAAGTCAAAACATTAGCGTTTGAAACTCTAATTTCCGATCCG
GCGCAAAATATTATGTTACGTGCCGGCGATGTCGTTTCGTTGCTAAACACGCCTTATAGCTTTACCGGTTTAGGTGCGGT
GGGTAACAACCAGCAAATGAAATTCTCAAGTAAAGGAATTACGCTTGCCGAAGCTATCGGTAAGATGGGTGGCCTAATTG
ATACTCGTTCGGATCCGAGAGGGGTATTCGTCTTCCGTCATGTGCCTTTTTCTCAATTAAGTTTAGATCAGCAAACACAA
TGGGGAGCGAAAGGCTATGGTATGGGTATGGATGTACCGACGGTTTATCGTGTGAATTTACTTGAGCCGCAATCACTGTT
TTTATTACAACGCTTCCCGATGCAAGATAAAGATATTGTCTATGTATCAAATGCACCGTTGTCCGAATTCCAAAAATTCT
TGAGAATGATTTTCTCGATTACTTCGCCGGTTACAAGTACGACTAATGCTATTCGTGCCTATTAA

Upstream 100 bases:

>100_bases
AATTTCTCTTGATTAGGTAACTTATTAAAATCAATCTTTATGTGGATTTTAAGACATACCTATATAGTTGTTATTCCTTA
ATATATTGAAGAGAAATTAG

Downstream 100 bases:

>100_bases
TATATTGAATTTATAAGGATAAAATATGGAAACAACTATTACGGCAAGTCCGACAGAAAAACTACAAAAACCGGTTAAAC
AGAAAAAAAGTTGGTTAAAA

Product: capsule polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKLIKLRLLLSLGLVASLAACSSLPTSGPSHSAILEANSQNSDKPLPEVNLVELDNGLVQQLYQTQQSQQFSGFLGTAGG
AGYAGAVNVGDVLEISIWEAPPAVLFGGTFSSEGQGSGHLTQLPAQMVNQNGTVTVPFVGNIRVAGKTPEAIQSQIVGAL
QRKANQPQVLVKIANNNSADVTVIRQGNSIRMPLSANNERVLDAVAAVGGTTENIEDVTVKLTRGSQVKTLAFETLISDP
AQNIMLRAGDVVSLLNTPYSFTGLGAVGNNQQMKFSSKGITLAEAIGKMGGLIDTRSDPRGVFVFRHVPFSQLSLDQQTQ
WGAKGYGMGMDVPTVYRVNLLEPQSLFLLQRFPMQDKDIVYVSNAPLSEFQKFLRMIFSITSPVTSTTNAIRAY

Sequences:

>Translated_394_residues
MKLIKLRLLLSLGLVASLAACSSLPTSGPSHSAILEANSQNSDKPLPEVNLVELDNGLVQQLYQTQQSQQFSGFLGTAGG
AGYAGAVNVGDVLEISIWEAPPAVLFGGTFSSEGQGSGHLTQLPAQMVNQNGTVTVPFVGNIRVAGKTPEAIQSQIVGAL
QRKANQPQVLVKIANNNSADVTVIRQGNSIRMPLSANNERVLDAVAAVGGTTENIEDVTVKLTRGSQVKTLAFETLISDP
AQNIMLRAGDVVSLLNTPYSFTGLGAVGNNQQMKFSSKGITLAEAIGKMGGLIDTRSDPRGVFVFRHVPFSQLSLDQQTQ
WGAKGYGMGMDVPTVYRVNLLEPQSLFLLQRFPMQDKDIVYVSNAPLSEFQKFLRMIFSITSPVTSTTNAIRAY
>Mature_394_residues
MKLIKLRLLLSLGLVASLAACSSLPTSGPSHSAILEANSQNSDKPLPEVNLVELDNGLVQQLYQTQQSQQFSGFLGTAGG
AGYAGAVNVGDVLEISIWEAPPAVLFGGTFSSEGQGSGHLTQLPAQMVNQNGTVTVPFVGNIRVAGKTPEAIQSQIVGAL
QRKANQPQVLVKIANNNSADVTVIRQGNSIRMPLSANNERVLDAVAAVGGTTENIEDVTVKLTRGSQVKTLAFETLISDP
AQNIMLRAGDVVSLLNTPYSFTGLGAVGNNQQMKFSSKGITLAEAIGKMGGLIDTRSDPRGVFVFRHVPFSQLSLDQQTQ
WGAKGYGMGMDVPTVYRVNLLEPQSLFLLQRFPMQDKDIVYVSNAPLSEFQKFLRMIFSITSPVTSTTNAIRAY

Specific function: May form an ATP-driven capsule polysaccharide export apparatus, in association with the BexA, BexB and BexC proteins. May function as a membrane anchor for capsular polysaccharides. Possible porin properties [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1788376, Length=395, Percent_Identity=27.0886075949367, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787218, Length=386, Percent_Identity=27.2020725388601, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715 [H]

Pfam domain/function: PF02563 Poly_export [H]

EC number: NA

Molecular weight: Translated: 42083; Mature: 42083

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIKLRLLLSLGLVASLAACSSLPTSGPSHSAILEANSQNSDKPLPEVNLVELDNGLVQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHH
QLYQTQQSQQFSGFLGTAGGAGYAGAVNVGDVLEISIWEAPPAVLFGGTFSSEGQGSGHL
HHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCH
TQLPAQMVNQNGTVTVPFVGNIRVAGKTPEAIQSQIVGALQRKANQPQVLVKIANNNSAD
HHCCHHHHCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
VTVIRQGNSIRMPLSANNERVLDAVAAVGGTTENIEDVTVKLTRGSQVKTLAFETLISDP
EEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCH
AQNIMLRAGDVVSLLNTPYSFTGLGAVGNNQQMKFSSKGITLAEAIGKMGGLIDTRSDPR
HHHHEEECCCCHHHHCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHCCEEECCCCCC
GVFVFRHVPFSQLSLDQQTQWGAKGYGMGMDVPTVYRVNLLEPQSLFLLQRFPMQDKDIV
EEEEEECCCHHHHCCCCHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCEE
YVSNAPLSEFQKFLRMIFSITSPVTSTTNAIRAY
EEECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MKLIKLRLLLSLGLVASLAACSSLPTSGPSHSAILEANSQNSDKPLPEVNLVELDNGLVQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHH
QLYQTQQSQQFSGFLGTAGGAGYAGAVNVGDVLEISIWEAPPAVLFGGTFSSEGQGSGHL
HHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCH
TQLPAQMVNQNGTVTVPFVGNIRVAGKTPEAIQSQIVGALQRKANQPQVLVKIANNNSAD
HHCCHHHHCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
VTVIRQGNSIRMPLSANNERVLDAVAAVGGTTENIEDVTVKLTRGSQVKTLAFETLISDP
EEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCH
AQNIMLRAGDVVSLLNTPYSFTGLGAVGNNQQMKFSSKGITLAEAIGKMGGLIDTRSDPR
HHHHEEECCCCHHHHCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHCCEEECCCCCC
GVFVFRHVPFSQLSLDQQTQWGAKGYGMGMDVPTVYRVNLLEPQSLFLLQRFPMQDKDIV
EEEEEECCCHHHHCCCCHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCEE
YVSNAPLSEFQKFLRMIFSITSPVTSTTNAIRAY
EEECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2082145 [H]