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The map label for this gene is insK [C]

Identifier: 126208965

GI number: 126208965

Start: 1716790

End: 1717572

Strand: Direct

Name: insK [C]

Synonym: APL_1501

Alternate gene names: 126208965

Gene position: 1716790-1717572 (Clockwise)

Preceding gene: 126208964

Following gene: 126208970

Centisome position: 75.48

GC content: 38.57

Gene sequence:

>783_bases
TTGACTGGTTTAAAACGTAGTACGTTCTTTTATCACTTACCGCCTAAAATCGATAAAAATGCAGTGATTAGGCAGAAAGT
GATTGAGATTTATCAAGATAATGATAGCAATTACGGCTATCGTCGTATTACGTTAAAGTTACGTGATTTTTTGGGTGCGA
TTAACCGTAAGCGTATTCAAAGGATAATGCAACAGCTTGATTTAAAAGGGAAATGTAAGCAGAGGAAATATCGTTCTTAT
CAAGGTGAAGCGGGTAAAATTGCCGAGAATGTATTGCAACGGGATTTTCACGCAACGGCGCCAAATGAAAAGCTCGTCAC
GGATATCACCGAGTTTAAATGTGCGGAAGGCAAGCTCTATTTATCGCCTATTAAGGACTTGTTTAATAGTGAAATTCTTG
CTTATGATTTAGCAAGAAGCCCTAACTTTGAGCAAGTGATGCGGATGCTAAAGCAAGCGGTCGCAAAACTGCCTAAGGAC
GCTAAACCGATTTTACATTCCGACCAAGGCTGGCAATACCGGATGGCAGACTATCAAGAAATGCTGAGAAAACATCATAT
TAAACAAAGTATGTCGAGAAAAGCGAATTGCTTGGATAATGGGGCAATGGAAAGTTTTTTTGGGCGATTGAAAACGGAAT
GTTACTTTGGTAAGCGATTTGAAACTTTCGAACAACTTGAGAAAGTGATTCACGAGTACATTCATTATTACAACAATGAG
CGTATTCAAGTGAAATTAAAAGGACTCAGCCCTGTACAATACAGAACTCAGTCCTTAAATTAA

Upstream 100 bases:

>100_bases
ACCTAAAAAAGTTGCGGGAGTTCAACCAACAAAAAATGCGGCAAAAGCAGCCATCGTAAAAACGTTGCGAGTGGATTTTC
CCTTAGAAATCCTCCTCCCT

Downstream 100 bases:

>100_bases
ACAGTCTAACTTTTTGGGGTCAGATCAAATTTGACCGCTTTTTTACTACTTACTTCGATTAAAGATTTTCAATCGCTTGG
TATTGCGTTTGAAGTTTCTC

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTGLKRSTFFYHLPPKIDKNAVIRQKVIEIYQDNDSNYGYRRITLKLRDFLGAINRKRIQRIMQQLDLKGKCKQRKYRSY
QGEAGKIAENVLQRDFHATAPNEKLVTDITEFKCAEGKLYLSPIKDLFNSEILAYDLARSPNFEQVMRMLKQAVAKLPKD
AKPILHSDQGWQYRMADYQEMLRKHHIKQSMSRKANCLDNGAMESFFGRLKTECYFGKRFETFEQLEKVIHEYIHYYNNE
RIQVKLKGLSPVQYRTQSLN

Sequences:

>Translated_260_residues
MTGLKRSTFFYHLPPKIDKNAVIRQKVIEIYQDNDSNYGYRRITLKLRDFLGAINRKRIQRIMQQLDLKGKCKQRKYRSY
QGEAGKIAENVLQRDFHATAPNEKLVTDITEFKCAEGKLYLSPIKDLFNSEILAYDLARSPNFEQVMRMLKQAVAKLPKD
AKPILHSDQGWQYRMADYQEMLRKHHIKQSMSRKANCLDNGAMESFFGRLKTECYFGKRFETFEQLEKVIHEYIHYYNNE
RIQVKLKGLSPVQYRTQSLN
>Mature_259_residues
TGLKRSTFFYHLPPKIDKNAVIRQKVIEIYQDNDSNYGYRRITLKLRDFLGAINRKRIQRIMQQLDLKGKCKQRKYRSYQ
GEAGKIAENVLQRDFHATAPNEKLVTDITEFKCAEGKLYLSPIKDLFNSEILAYDLARSPNFEQVMRMLKQAVAKLPKDA
KPILHSDQGWQYRMADYQEMLRKHHIKQSMSRKANCLDNGAMESFFGRLKTECYFGKRFETFEQLEKVIHEYIHYYNNER
IQVKLKGLSPVQYRTQSLN

Specific function: Involved in the transposition of the insertion sequence is150 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=192, Percent_Identity=27.0833333333333, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789981, Length=257, Percent_Identity=53.307392996109, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1788405, Length=236, Percent_Identity=32.6271186440678, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787263, Length=236, Percent_Identity=32.6271186440678, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786753, Length=236, Percent_Identity=32.6271186440678, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786570, Length=236, Percent_Identity=32.6271186440678, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786490, Length=236, Percent_Identity=32.6271186440678, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30791; Mature: 30660

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
TGLKRSTFFYHLPPKIDKNAVIRQKVIEIYQDNDSNYGYRRITLKLRDFLGAINRKRIQ
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
RIMQQLDLKGKCKQRKYRSYQGEAGKIAENVLQRDFHATAPNEKLVTDITEFKCAEGKLY
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
LSPIKDLFNSEILAYDLARSPNFEQVMRMLKQAVAKLPKDAKPILHSDQGWQYRMADYQE
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHH
MLRKHHIKQSMSRKANCLDNGAMESFFGRLKTECYFGKRFETFEQLEKVIHEYIHYYNNE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
RIQVKLKGLSPVQYRTQSLN
EEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]