Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 126208952

GI number: 126208952

Start: 1703581

End: 1704315

Strand: Reverse

Name: plsC [H]

Synonym: APL_1488

Alternate gene names: 126208952

Gene position: 1704315-1703581 (Counterclockwise)

Preceding gene: 126208955

Following gene: 126208951

Centisome position: 74.93

GC content: 45.31

Gene sequence:

>735_bases
ATGTTAAAAATTCTTCGTATCTTTTTAATCGCCGTCCTCGCGATTATGATTTCCCTTATCGGAACACTCTATGCGTTTGT
GCGTTTTCGCCATCCGAGTTCGGTCGGCGTCGTCGCTAAAATGTATGCGGCGATGCATCGTTTAGTCGGCTTAAAAGTCA
TTTACCGCCCTCGTCCGGCATTTAATCAGTCGGCGATTTACATCGCTAATCATCAAAACAATTACGATATGCTTACCATT
GCCGGTATGGTGCCGCCTCGCACGGTAACCATCGGTAAAAAGAGTCTGATTTGGATTCCGTTTTTCGGCTTGGTTTATTG
GGCGACCGGTAATATCTTTATCAACCGTGAAAAGCGCAGTAGTGCGATCAGCACAATGAATAAAGTCGGGGAAATTATTC
GCGAACGTCAAATTTCGATTTGGATGTTCCCGGAAGGTACCCGCAGCCGCGGCAGAGGTTTATTACCGTTTAAAACCGGT
GCATTCCACACGGCAATTGCCGCCGGCGTGCCGATTGTACCTATCGTCTGTTCTTCGCTACATAATAAAGTCGATTTAAA
CCGTTGGAATAACGGCGTGGTCATTTGTGAAACGTTAGAACCGATCGATACCAGCGGTTACAACCGTGATAACATCAAAG
AATTAATCGAAAAAAGTTATGCCGTGATGTCGGCGAAAATCGAAGCGTTAGATGCGGAAGTTGCCGCATTGGAAGCCAAT
AAAAAAACAAAGTAA

Upstream 100 bases:

>100_bases
TTTTATTCCGCATTTAAACCTTTTAATAAAATAAGTAAAATTTGCTATACTTCGGTAAATTTTTAAGAAGCGTCGTCTTC
ATTTAAACTCAAGGTTATTT

Downstream 100 bases:

>100_bases
TTAAGATGATGAATCTGACCAGAAGACAATTACTTACTCGTTCGGCGGTTGCCGCAACGATGTTTTCCGCACCGAAAACC
TTATGGGCGGCGGAACGCCA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MLKILRIFLIAVLAIMISLIGTLYAFVRFRHPSSVGVVAKMYAAMHRLVGLKVIYRPRPAFNQSAIYIANHQNNYDMLTI
AGMVPPRTVTIGKKSLIWIPFFGLVYWATGNIFINREKRSSAISTMNKVGEIIRERQISIWMFPEGTRSRGRGLLPFKTG
AFHTAIAAGVPIVPIVCSSLHNKVDLNRWNNGVVICETLEPIDTSGYNRDNIKELIEKSYAVMSAKIEALDAEVAALEAN
KKTK

Sequences:

>Translated_244_residues
MLKILRIFLIAVLAIMISLIGTLYAFVRFRHPSSVGVVAKMYAAMHRLVGLKVIYRPRPAFNQSAIYIANHQNNYDMLTI
AGMVPPRTVTIGKKSLIWIPFFGLVYWATGNIFINREKRSSAISTMNKVGEIIRERQISIWMFPEGTRSRGRGLLPFKTG
AFHTAIAAGVPIVPIVCSSLHNKVDLNRWNNGVVICETLEPIDTSGYNRDNIKELIEKSYAVMSAKIEALDAEVAALEAN
KKTK
>Mature_244_residues
MLKILRIFLIAVLAIMISLIGTLYAFVRFRHPSSVGVVAKMYAAMHRLVGLKVIYRPRPAFNQSAIYIANHQNNYDMLTI
AGMVPPRTVTIGKKSLIWIPFFGLVYWATGNIFINREKRSSAISTMNKVGEIIRERQISIWMFPEGTRSRGRGLLPFKTG
AFHTAIAAGVPIVPIVCSSLHNKVDLNRWNNGVVICETLEPIDTSGYNRDNIKELIEKSYAVMSAKIEALDAEVAALEAN
KKTK

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=216, Percent_Identity=35.1851851851852, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI15100175, Length=216, Percent_Identity=35.1851851851852, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI6041665, Length=224, Percent_Identity=29.4642857142857, Blast_Score=121, Evalue=5e-28,
Organism=Escherichia coli, GI1789395, Length=245, Percent_Identity=51.8367346938776, Blast_Score=258, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17564032, Length=181, Percent_Identity=33.7016574585635, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17568319, Length=238, Percent_Identity=30.672268907563, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320151, Length=254, Percent_Identity=32.6771653543307, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281364648, Length=243, Percent_Identity=28.8065843621399, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24582856, Length=243, Percent_Identity=28.8065843621399, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24582854, Length=243, Percent_Identity=28.8065843621399, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24641614, Length=194, Percent_Identity=35.5670103092784, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24641612, Length=194, Percent_Identity=35.5670103092784, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27293; Mature: 27293

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKILRIFLIAVLAIMISLIGTLYAFVRFRHPSSVGVVAKMYAAMHRLVGLKVIYRPRPA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCC
FNQSAIYIANHQNNYDMLTIAGMVPPRTVTIGKKSLIWIPFFGLVYWATGNIFINREKRS
CCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCEEEEEEHHHHHHHCCCCEEEECCHHH
SAISTMNKVGEIIRERQISIWMFPEGTRSRGRGLLPFKTGAFHTAIAAGVPIVPIVCSSL
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHH
HNKVDLNRWNNGVVICETLEPIDTSGYNRDNIKELIEKSYAVMSAKIEALDAEVAALEAN
HCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
KKTK
CCCC
>Mature Secondary Structure
MLKILRIFLIAVLAIMISLIGTLYAFVRFRHPSSVGVVAKMYAAMHRLVGLKVIYRPRPA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCC
FNQSAIYIANHQNNYDMLTIAGMVPPRTVTIGKKSLIWIPFFGLVYWATGNIFINREKRS
CCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCEEEEEEHHHHHHHCCCCEEEECCHHH
SAISTMNKVGEIIRERQISIWMFPEGTRSRGRGLLPFKTGAFHTAIAAGVPIVPIVCSSL
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHH
HNKVDLNRWNNGVVICETLEPIDTSGYNRDNIKELIEKSYAVMSAKIEALDAEVAALEAN
HCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
KKTK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]