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The map label for this gene is slyD [H]

Identifier: 126208920

GI number: 126208920

Start: 1670166

End: 1670762

Strand: Reverse

Name: slyD [H]

Synonym: APL_1456

Alternate gene names: 126208920

Gene position: 1670762-1670166 (Counterclockwise)

Preceding gene: 126208921

Following gene: 126208919

Centisome position: 73.46

GC content: 46.73

Gene sequence:

>597_bases
ATGAAAATCGCAAAAAATGTTGTTCCAAGCATTGCTTACCAAGTTCGTACGCAAGACGGTGTGTTAGTTGATGAAGCGCC
GGTAAACCAACCGTTAGAATATTTACACGGTCATAACAACCTTGTTGAAGGTTTGGAAAAAGCACTTGAAGGCAAAGCAG
TAGGTGATGTTTTTGAAGTTCGCGTTAAACCGGAAGAAGGTTACGGCGAATACAATGAAAACATGGTTCAACGCGTACCG
AAAGACGTCTTTATGGGTGTTGATGAATTAGAAGTCGGTATGCGTTTTATCGCAGATACCGATTTAGGTCCGTTACCGGT
TGTTATCACTGAAGTGGACGGTGACGAAGTGGTGGTTGATGGTAACCATATGTTAGCCGGGCAAGAGTTATTATTCTCTG
TTGAAGTAGTTGCAACCCGTGAAGCGACATTAGAAGAAATCGCACACGGTCATATTCATTCCGGTCATGAACACGAAGGT
TGCTGCGGCGGTCACGGTGAAGAAGGCGGCTGCGGATGCGGCAGTCATGATCATCATCACGACCACGATCATCACCACGG
GCATGGCGGTTGCGGTTGTGGCGGTCACCACCACTAA

Upstream 100 bases:

>100_bases
GCGGTCATTTTATTTCTATTTTTTGCAAACCTTTTGCAAATCTACGATAAACCGCTACAATGAAGCGTATTTTTACCTAA
ATAGAAAAAAGGAATCCTTA

Downstream 100 bases:

>100_bases
TTCTTTTTTATTTCATCATTGGCGCAAGCGTTATCGCTTGTGCCTTTTTAGTTTTTTTTCAAACAATAACCTGACGTACC
CTTCAATACGCCGATATAAA

Product: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKIAKNVVPSIAYQVRTQDGVLVDEAPVNQPLEYLHGHNNLVEGLEKALEGKAVGDVFEVRVKPEEGYGEYNENMVQRVP
KDVFMGVDELEVGMRFIADTDLGPLPVVITEVDGDEVVVDGNHMLAGQELLFSVEVVATREATLEEIAHGHIHSGHEHEG
CCGGHGEEGGCGCGSHDHHHDHDHHHGHGGCGCGGHHH

Sequences:

>Translated_198_residues
MKIAKNVVPSIAYQVRTQDGVLVDEAPVNQPLEYLHGHNNLVEGLEKALEGKAVGDVFEVRVKPEEGYGEYNENMVQRVP
KDVFMGVDELEVGMRFIADTDLGPLPVVITEVDGDEVVVDGNHMLAGQELLFSVEVVATREATLEEIAHGHIHSGHEHEG
CCGGHGEEGGCGCGSHDHHHDHDHHHGHGGCGCGGHHH
>Mature_198_residues
MKIAKNVVPSIAYQVRTQDGVLVDEAPVNQPLEYLHGHNNLVEGLEKALEGKAVGDVFEVRVKPEEGYGEYNENMVQRVP
KDVFMGVDELEVGMRFIADTDLGPLPVVITEVDGDEVVVDGNHMLAGQELLFSVEVVATREATLEEIAHGHIHSGHEHEG
CCGGHGEEGGCGCGSHDHHHDHDHHHGHGGCGCGGHHH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=70.2702702702703, Blast_Score=210, Evalue=6e-56,
Organism=Escherichia coli, GI1786211, Length=128, Percent_Identity=34.375, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21397; Mature: 21397

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAKNVVPSIAYQVRTQDGVLVDEAPVNQPLEYLHGHNNLVEGLEKALEGKAVGDVFEV
CCCHHHHHHHHHEEEECCCCEEECCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEE
RVKPEEGYGEYNENMVQRVPKDVFMGVDELEVGMRFIADTDLGPLPVVITEVDGDEVVVD
EECCCCCCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQELLFSVEVVATREATLEEIAHGHIHSGHEHEGCCGGHGEEGGCGCGSHDHHH
CCEEEECHHHHEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DHDHHHGHGGCGCGGHHH
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIAKNVVPSIAYQVRTQDGVLVDEAPVNQPLEYLHGHNNLVEGLEKALEGKAVGDVFEV
CCCHHHHHHHHHEEEECCCCEEECCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEE
RVKPEEGYGEYNENMVQRVPKDVFMGVDELEVGMRFIADTDLGPLPVVITEVDGDEVVVD
EECCCCCCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQELLFSVEVVATREATLEEIAHGHIHSGHEHEGCCGGHGEEGGCGCGSHDHHH
CCEEEECHHHHEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DHDHHHGHGGCGCGGHHH
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]