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The map label for this gene is mqo

Identifier: 126208878

GI number: 126208878

Start: 1616829

End: 1618304

Strand: Reverse

Name: mqo

Synonym: APL_1414

Alternate gene names: 126208878

Gene position: 1618304-1616829 (Counterclockwise)

Preceding gene: 126208879

Following gene: 126208877

Centisome position: 71.15

GC content: 45.33

Gene sequence:

>1476_bases
ATGCAGGATTCTAGCTCTGCTTTAGAAAGTTATTCTGATGTAACGCTGATTGGTGCAGGGATTATGAGCGGAACGCTCGG
CGCATTTTTAACCGAATTGGCACCGGAAAAAAGTCTTGCGATTTTTGAGAAGCTTTCGGCAGTCGGTTTAGAAAGTTCAA
ATGAATGGAATAATGCCGGCACGGGGCATTCCGCATTATGCGAGCTAAATTATACCGAACAGAAAGCAAACGGCGAAGTT
TCGGTCGAGCGTGCCGTTAAAATCTGTGAAGATTTCCAGCTTTCGTTGCAACTTTGGAGCTATTTGGTTGAAACGGGAAG
AATCCAAGCTCCGAGAGAGTTTATTCACCGTATTCCGCATATCAGTTTCGTACAAGGCGAGCAAAATGCGCAGTTTTTAC
AAAAGCGTTATCAAAGTTTAGCCCAAAGTCATTTGTTCGAAGGTATGCAGTTTAGCCGAGATCATCAACAGCTTGCGCAG
TGGATGCCGTTGATGATGCAAAATCGAGATTCGAACGAAACATTAGCCGCAAGTTATATTCAGTACGGTACGGACGTAAA
CTTCGGCGAGCTGACGCGAAAATTGTTCGATTATTTAGTGAAGCAAAAAGCGGAGTTAAATTTAAATCATACGGTTAAAA
ATATACAACGTTTAGCGAACGGCGAGTGGAAATTAACCGTTGTGGATCAGCAAGGTCAAAAGCGAGTGCATCGTAGTAAA
TTCGTGTTTATCGGCGGTGGCGGCGGTGCGTTACCTTTATTACAAAAATCCGGTATTACCGACGGTAAAAATGTCGGCGG
TTTCCCGGTCAGCGGTTTATTTATGGTGTGTAATAATCCTGAGGTGATTGCCAAACATAATGCCAAGGTTTATGGCAAAG
CGAAATTAGGTGCGCCGCCGATGTCGGTACCTCATTTGGATACTCGCTTTATCGAAGGCAAACAATCGCTGTTATTCGGG
CCTTTTGCCGGCTTTACGCTGAAATTTTTAAAACAGGGAAGCGTTTTAGATCTGCCGACTTCGGTTACACCGACTAATTT
CTGTTCCGTAACCAAAGCCGGTATCAAAAACCTACCGCTTGCCCATTATTTAATGAAGCAAGCGATGCTGACCAAAGCAC
AGCGTATGGCGGATTTACGTGAGTTTGTACCGGATGCGAAAGACGAAGATTGGGACGTCGTGGTGGCAGGACAACGCGTG
CAAGTGATTAAAGGCGGTGAAATGCGCTTCGGTACCGAAGTGATTCGTGCGGAAGACGGTTCTTTAGCCGCATTGTTGGG
GGCTTCGCCAGGCGCTTCAACTTCGGTAAAAGCAATGTTGGACGTATTGGTTTCATGCTTTGCTGCGGAGCTACCGCAAT
GGCAAGCCAAATTAACCCAAATGTTGCCTTCTTACGGAAAAGCGTTACGCAACGAACCGCAATTATATGCACAAATTAAG
CAACGTGTAGATCAGGTGTTAGCGTTAGCAAATTAG

Upstream 100 bases:

>100_bases
AATTTGACTAATTGTGCTAAAAATGTGATCTTGTTCACACTTATGTTACTCTATTCACGCTATAATTTCACAAAAAATTA
ACACAATAAAAGGGAACACT

Downstream 100 bases:

>100_bases
AAAATACAAGCGGTCGAATTTTTCGGAAATTTTGCAAATTTATCCGAAAATTCGACCGCTTGCTTTTTGAGCAAACTCGC
CGTTTCAGCGCACAGTTGTA

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MQDSSSALESYSDVTLIGAGIMSGTLGAFLTELAPEKSLAIFEKLSAVGLESSNEWNNAGTGHSALCELNYTEQKANGEV
SVERAVKICEDFQLSLQLWSYLVETGRIQAPREFIHRIPHISFVQGEQNAQFLQKRYQSLAQSHLFEGMQFSRDHQQLAQ
WMPLMMQNRDSNETLAASYIQYGTDVNFGELTRKLFDYLVKQKAELNLNHTVKNIQRLANGEWKLTVVDQQGQKRVHRSK
FVFIGGGGGALPLLQKSGITDGKNVGGFPVSGLFMVCNNPEVIAKHNAKVYGKAKLGAPPMSVPHLDTRFIEGKQSLLFG
PFAGFTLKFLKQGSVLDLPTSVTPTNFCSVTKAGIKNLPLAHYLMKQAMLTKAQRMADLREFVPDAKDEDWDVVVAGQRV
QVIKGGEMRFGTEVIRAEDGSLAALLGASPGASTSVKAMLDVLVSCFAAELPQWQAKLTQMLPSYGKALRNEPQLYAQIK
QRVDQVLALAN

Sequences:

>Translated_491_residues
MQDSSSALESYSDVTLIGAGIMSGTLGAFLTELAPEKSLAIFEKLSAVGLESSNEWNNAGTGHSALCELNYTEQKANGEV
SVERAVKICEDFQLSLQLWSYLVETGRIQAPREFIHRIPHISFVQGEQNAQFLQKRYQSLAQSHLFEGMQFSRDHQQLAQ
WMPLMMQNRDSNETLAASYIQYGTDVNFGELTRKLFDYLVKQKAELNLNHTVKNIQRLANGEWKLTVVDQQGQKRVHRSK
FVFIGGGGGALPLLQKSGITDGKNVGGFPVSGLFMVCNNPEVIAKHNAKVYGKAKLGAPPMSVPHLDTRFIEGKQSLLFG
PFAGFTLKFLKQGSVLDLPTSVTPTNFCSVTKAGIKNLPLAHYLMKQAMLTKAQRMADLREFVPDAKDEDWDVVVAGQRV
QVIKGGEMRFGTEVIRAEDGSLAALLGASPGASTSVKAMLDVLVSCFAAELPQWQAKLTQMLPSYGKALRNEPQLYAQIK
QRVDQVLALAN
>Mature_491_residues
MQDSSSALESYSDVTLIGAGIMSGTLGAFLTELAPEKSLAIFEKLSAVGLESSNEWNNAGTGHSALCELNYTEQKANGEV
SVERAVKICEDFQLSLQLWSYLVETGRIQAPREFIHRIPHISFVQGEQNAQFLQKRYQSLAQSHLFEGMQFSRDHQQLAQ
WMPLMMQNRDSNETLAASYIQYGTDVNFGELTRKLFDYLVKQKAELNLNHTVKNIQRLANGEWKLTVVDQQGQKRVHRSK
FVFIGGGGGALPLLQKSGITDGKNVGGFPVSGLFMVCNNPEVIAKHNAKVYGKAKLGAPPMSVPHLDTRFIEGKQSLLFG
PFAGFTLKFLKQGSVLDLPTSVTPTNFCSVTKAGIKNLPLAHYLMKQAMLTKAQRMADLREFVPDAKDEDWDVVVAGQRV
QVIKGGEMRFGTEVIRAEDGSLAALLGASPGASTSVKAMLDVLVSCFAAELPQWQAKLTQMLPSYGKALRNEPQLYAQIK
QRVDQVLALAN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=490, Percent_Identity=50.4081632653061, Blast_Score=498, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_ACTP2 (A3N262)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054103.1
- ProteinModelPortal:   A3N262
- STRING:   A3N262
- GeneID:   4850549
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1414
- eggNOG:   COG0579
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- PhylomeDB:   A3N262
- ProtClustDB:   PRK05257
- BioCyc:   APLE416269:APL_1414-MONOMER
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 54075; Mature: 54075

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSSSALESYSDVTLIGAGIMSGTLGAFLTELAPEKSLAIFEKLSAVGLESSNEWNNAG
CCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC
TGHSALCELNYTEQKANGEVSVERAVKICEDFQLSLQLWSYLVETGRIQAPREFIHRIPH
CCCCEEEEECCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
ISFVQGEQNAQFLQKRYQSLAQSHLFEGMQFSRDHQQLAQWMPLMMQNRDSNETLAASYI
CEEECCCCHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QYGTDVNFGELTRKLFDYLVKQKAELNLNHTVKNIQRLANGEWKLTVVDQQGQKRVHRSK
HHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCC
FVFIGGGGGALPLLQKSGITDGKNVGGFPVSGLFMVCNNPEVIAKHNAKVYGKAKLGAPP
EEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCEEEEEEECCCCC
MSVPHLDTRFIEGKQSLLFGPFAGFTLKFLKQGSVLDLPTSVTPTNFCSVTKAGIKNLPL
CCCCCCCHHHHCCCHHEEECCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCCH
AHYLMKQAMLTKAQRMADLREFVPDAKDEDWDVVVAGQRVQVIKGGEMRFGTEVIRAEDG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCEECCCHHEEECCC
SLAALLGASPGASTSVKAMLDVLVSCFAAELPQWQAKLTQMLPSYGKALRNEPQLYAQIK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QRVDQVLALAN
HHHHHHHHCCC
>Mature Secondary Structure
MQDSSSALESYSDVTLIGAGIMSGTLGAFLTELAPEKSLAIFEKLSAVGLESSNEWNNAG
CCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCC
TGHSALCELNYTEQKANGEVSVERAVKICEDFQLSLQLWSYLVETGRIQAPREFIHRIPH
CCCCEEEEECCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
ISFVQGEQNAQFLQKRYQSLAQSHLFEGMQFSRDHQQLAQWMPLMMQNRDSNETLAASYI
CEEECCCCHHHHHHHHHHHHHHHHHHHCHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QYGTDVNFGELTRKLFDYLVKQKAELNLNHTVKNIQRLANGEWKLTVVDQQGQKRVHRSK
HHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCC
FVFIGGGGGALPLLQKSGITDGKNVGGFPVSGLFMVCNNPEVIAKHNAKVYGKAKLGAPP
EEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCEEEEEEECCCCC
MSVPHLDTRFIEGKQSLLFGPFAGFTLKFLKQGSVLDLPTSVTPTNFCSVTKAGIKNLPL
CCCCCCCHHHHCCCHHEEECCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCCH
AHYLMKQAMLTKAQRMADLREFVPDAKDEDWDVVVAGQRVQVIKGGEMRFGTEVIRAEDG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCEECCCHHEEECCC
SLAALLGASPGASTSVKAMLDVLVSCFAAELPQWQAKLTQMLPSYGKALRNEPQLYAQIK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QRVDQVLALAN
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA