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The map label for this gene is dipZ

Identifier: 126208823

GI number: 126208823

Start: 1555432

End: 1557183

Strand: Direct

Name: dipZ

Synonym: APL_1359

Alternate gene names: 126208823

Gene position: 1555432-1557183 (Clockwise)

Preceding gene: 126208820

Following gene: 126208824

Centisome position: 68.39

GC content: 44.92

Gene sequence:

>1752_bases
ATGCTAAAACGTTTTATTTTTCTCTTGGTCGGCATAACGCTAACCCTTTCCGCACACGCCGGTTTATTCGGTAACGACCA
ACCCAAATATTTGAGCGGAGCCGAAGCATTCGCTTTTTCCGCCACACCGAAATCCGATAAACAAATTGAGCTGAACTGGC
AAATTGCCGACGGTTATTATCTGTATAAAAAAGAAATACAGGTCACGCCGCAAAATGCCGAAATCCAACCGTTAGCGTTC
CCTGCTGCGGAAAATTATCACGATGAGTTTTTCGGTGAGGTGGAAATTTTCCGTAATCAGCTGACGTTGCCGATAACGTT
CTCTGCAGAACAAGCGAACGCTAGTCTTTCGGTTCATTATCAAGGCTGTACCAAAGGTTTCTGCTATCCGCCCGAAACGG
TCACCGTTAGTTTAGACGGGCAACAAGCGGTCGATTCCGCTCAAAATGTTGCAAAAAATAGAGAAAATTCAACCGCTTCT
CAGCCTTTGGCTAATGCACCGAAAGCGGAACAGGATCAGCTTGCCGAGAATTTAGCGAACAATCGCTTATCGATTTTTTG
GTTCTTTTTACTGGGTATCGGTTTAGCCTTTACCCCGTGCGTATTACCAATGCTGCCGTTATTATCTGCAATTGTGATTG
GCAATAAGCAACGCCCTAATACGTTCAAAGCTTTATTACTCAGCTTTGCTTACGTACAAGGTATGGCGCTTACTTATACG
CTATTAGGCTTAGTGGTGGCGGCGATCGGCTTACCGTTCCAAGTGGCGTTGCAAAGCCCGCCGGTGCTGATTTCGCTTGC
GATTTTATTCACTATTTTAGCCGCTTCGATGTTCGGCTTATTTGAAATCCGTTTGCCGAATTCATGGCAGCAAAAACTGA
ATGCAATGAGCCAAAAACAGCAAGGCGGTGCATTTGGTAGCGTATTTGTAATGGGGATGATTGCCGGCTTAGTGGCTTCG
CCTTGTACTTCGGCGCCGTTATCCGGCGCATTGCTGTATGTTGCCCAAAGTGGGGACTTGCTCACCGGCGGATTAGCACT
CTATTTATTAGCCTTAGGAATGGGGATTCCGTTAATTCTGATTACCTTATTCGGCAACCGTATTTTACCGAAATCGGGCG
ATTGGTTATTAAAAGTCAAAACCGCCTTCGGTTTCGTGATGTTAGCCTTACCGGTCTTTTTACTTAGCCGTATTTTACCG
AGCCATTATGAGCCGTTGATGTGGTCGGCGCTGGCAATGGTGTTTGTCGGCTGGTTGATTAGCGTGATTCCGACACAAGG
CGTCATCAAACAAGCGGTTAGAATTGTACTGTTTCTTACCTTTGCGGTTGCTTCTTACCCTTGGGCGAATTTAGTATGGA
ATCAAGGCAACAGTAGCCATTCGGCACAAGTAAGCAACCACTTAGCGTTTGAACGCGTACAATCCCTTGCAGAATTACAG
GAAAAATTGACCGCTTCACAGGGCAAAAAAGTGATGTTGGATCTGTATGCCGACTGGTGTGTCGCCTGTAAGGAGTTTGA
GAAATACACCTTTACCGACCAAGCTGTACAGCAAAAATTAGCTGAGATGGTGGTATTACAAGTGGATATGACCAATAATT
CGGCACAAAACGATGAGCTGATGAAACACTTCAACGTACTAGGTTTACCGACCATTTTATTCTTTGATGAGAGCGGTAAG
GAACTGACACAATCAAGAGTTACCGGCTTCTTAGAAGCAAATCAATTTTTAAATTGGCTAAATCAGTTATAA

Upstream 100 bases:

>100_bases
TTTAAGAAATATTCACGATTTTTGTTGTAAGAAGCAGGCATTTTGCCTGACCTTACTTATTTATATTACAATACGTCACC
TTTTATCTTTCTATATCGAT

Downstream 100 bases:

>100_bases
TCTCACGGCACAAGTTGATCGCTTGTGCCATTTTTTATTAATCACAATAAGTTTGCTATGAACCAAGACAATCATAAAAT
TAAAGACATTATTCGTATTT

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MLKRFIFLLVGITLTLSAHAGLFGNDQPKYLSGAEAFAFSATPKSDKQIELNWQIADGYYLYKKEIQVTPQNAEIQPLAF
PAAENYHDEFFGEVEIFRNQLTLPITFSAEQANASLSVHYQGCTKGFCYPPETVTVSLDGQQAVDSAQNVAKNRENSTAS
QPLANAPKAEQDQLAENLANNRLSIFWFFLLGIGLAFTPCVLPMLPLLSAIVIGNKQRPNTFKALLLSFAYVQGMALTYT
LLGLVVAAIGLPFQVALQSPPVLISLAILFTILAASMFGLFEIRLPNSWQQKLNAMSQKQQGGAFGSVFVMGMIAGLVAS
PCTSAPLSGALLYVAQSGDLLTGGLALYLLALGMGIPLILITLFGNRILPKSGDWLLKVKTAFGFVMLALPVFLLSRILP
SHYEPLMWSALAMVFVGWLISVIPTQGVIKQAVRIVLFLTFAVASYPWANLVWNQGNSSHSAQVSNHLAFERVQSLAELQ
EKLTASQGKKVMLDLYADWCVACKEFEKYTFTDQAVQQKLAEMVVLQVDMTNNSAQNDELMKHFNVLGLPTILFFDESGK
ELTQSRVTGFLEANQFLNWLNQL

Sequences:

>Translated_583_residues
MLKRFIFLLVGITLTLSAHAGLFGNDQPKYLSGAEAFAFSATPKSDKQIELNWQIADGYYLYKKEIQVTPQNAEIQPLAF
PAAENYHDEFFGEVEIFRNQLTLPITFSAEQANASLSVHYQGCTKGFCYPPETVTVSLDGQQAVDSAQNVAKNRENSTAS
QPLANAPKAEQDQLAENLANNRLSIFWFFLLGIGLAFTPCVLPMLPLLSAIVIGNKQRPNTFKALLLSFAYVQGMALTYT
LLGLVVAAIGLPFQVALQSPPVLISLAILFTILAASMFGLFEIRLPNSWQQKLNAMSQKQQGGAFGSVFVMGMIAGLVAS
PCTSAPLSGALLYVAQSGDLLTGGLALYLLALGMGIPLILITLFGNRILPKSGDWLLKVKTAFGFVMLALPVFLLSRILP
SHYEPLMWSALAMVFVGWLISVIPTQGVIKQAVRIVLFLTFAVASYPWANLVWNQGNSSHSAQVSNHLAFERVQSLAELQ
EKLTASQGKKVMLDLYADWCVACKEFEKYTFTDQAVQQKLAEMVVLQVDMTNNSAQNDELMKHFNVLGLPTILFFDESGK
ELTQSRVTGFLEANQFLNWLNQL
>Mature_583_residues
MLKRFIFLLVGITLTLSAHAGLFGNDQPKYLSGAEAFAFSATPKSDKQIELNWQIADGYYLYKKEIQVTPQNAEIQPLAF
PAAENYHDEFFGEVEIFRNQLTLPITFSAEQANASLSVHYQGCTKGFCYPPETVTVSLDGQQAVDSAQNVAKNRENSTAS
QPLANAPKAEQDQLAENLANNRLSIFWFFLLGIGLAFTPCVLPMLPLLSAIVIGNKQRPNTFKALLLSFAYVQGMALTYT
LLGLVVAAIGLPFQVALQSPPVLISLAILFTILAASMFGLFEIRLPNSWQQKLNAMSQKQQGGAFGSVFVMGMIAGLVAS
PCTSAPLSGALLYVAQSGDLLTGGLALYLLALGMGIPLILITLFGNRILPKSGDWLLKVKTAFGFVMLALPVFLLSRILP
SHYEPLMWSALAMVFVGWLISVIPTQGVIKQAVRIVLFLTFAVASYPWANLVWNQGNSSHSAQVSNHLAFERVQSLAELQ
EKLTASQGKKVMLDLYADWCVACKEFEKYTFTDQAVQQKLAEMVVLQVDMTNNSAQNDELMKHFNVLGLPTILFFDESGK
ELTQSRVTGFLEANQFLNWLNQL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1790578, Length=576, Percent_Identity=52.9513888888889, Blast_Score=570, Evalue=1e-164,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBD_ACTP2 (A3N207)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054048.1
- ProteinModelPortal:   A3N207
- STRING:   A3N207
- GeneID:   4849875
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1359
- eggNOG:   COG4232
- HOGENOM:   HBG640883
- OMA:   SAQNDEL
- PhylomeDB:   A3N207
- ProtClustDB:   PRK00293
- BioCyc:   APLE416269:APL_1359-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00399
- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin; SSF52833 Thiordxn-like_fd

EC number: =1.8.1.8

Molecular weight: Translated: 64037; Mature: 64037

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e5d3f80)-; HASH(0x1c1bade4)-; HASH(0x1da36754)-; HASH(0x1e20d158)-; HASH(0x1e42d0b4)-; HASH(0x1db6c78c)-; HASH(0x1be0f26c)-; HASH(0x1dbb5658)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRFIFLLVGITLTLSAHAGLFGNDQPKYLSGAEAFAFSATPKSDKQIELNWQIADGYY
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCEE
LYKKEIQVTPQNAEIQPLAFPAAENYHDEFFGEVEIFRNQLTLPITFSAEQANASLSVHY
EEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEE
QGCTKGFCYPPETVTVSLDGQQAVDSAQNVAKNRENSTASQPLANAPKAEQDQLAENLAN
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NRLSIFWFFLLGIGLAFTPCVLPMLPLLSAIVIGNKQRPNTFKALLLSFAYVQGMALTYT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLGLVVAAIGLPFQVALQSPPVLISLAILFTILAASMFGLFEIRLPNSWQQKLNAMSQKQ
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHH
QGGAFGSVFVMGMIAGLVASPCTSAPLSGALLYVAQSGDLLTGGLALYLLALGMGIPLIL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHCCHHHHH
ITLFGNRILPKSGDWLLKVKTAFGFVMLALPVFLLSRILPSHYEPLMWSALAMVFVGWLI
HHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SVIPTQGVIKQAVRIVLFLTFAVASYPWANLVWNQGNSSHSAQVSNHLAFERVQSLAELQ
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EKLTASQGKKVMLDLYADWCVACKEFEKYTFTDQAVQQKLAEMVVLQVDMTNNSAQNDEL
HHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHH
MKHFNVLGLPTILFFDESGKELTQSRVTGFLEANQFLNWLNQL
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLKRFIFLLVGITLTLSAHAGLFGNDQPKYLSGAEAFAFSATPKSDKQIELNWQIADGYY
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCEE
LYKKEIQVTPQNAEIQPLAFPAAENYHDEFFGEVEIFRNQLTLPITFSAEQANASLSVHY
EEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEE
QGCTKGFCYPPETVTVSLDGQQAVDSAQNVAKNRENSTASQPLANAPKAEQDQLAENLAN
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHC
NRLSIFWFFLLGIGLAFTPCVLPMLPLLSAIVIGNKQRPNTFKALLLSFAYVQGMALTYT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLGLVVAAIGLPFQVALQSPPVLISLAILFTILAASMFGLFEIRLPNSWQQKLNAMSQKQ
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHH
QGGAFGSVFVMGMIAGLVASPCTSAPLSGALLYVAQSGDLLTGGLALYLLALGMGIPLIL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHCCHHHHH
ITLFGNRILPKSGDWLLKVKTAFGFVMLALPVFLLSRILPSHYEPLMWSALAMVFVGWLI
HHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SVIPTQGVIKQAVRIVLFLTFAVASYPWANLVWNQGNSSHSAQVSNHLAFERVQSLAELQ
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EKLTASQGKKVMLDLYADWCVACKEFEKYTFTDQAVQQKLAEMVVLQVDMTNNSAQNDEL
HHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHH
MKHFNVLGLPTILFFDESGKELTQSRVTGFLEANQFLNWLNQL
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA