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The map label for this gene is argR

Identifier: 126208761

GI number: 126208761

Start: 1484482

End: 1484943

Strand: Reverse

Name: argR

Synonym: APL_1295

Alternate gene names: 126208761

Gene position: 1484943-1484482 (Counterclockwise)

Preceding gene: 126208764

Following gene: 126208760

Centisome position: 65.29

GC content: 43.07

Gene sequence:

>462_bases
ATGGAAAAGCTTGATAAGTTATCCGAAGCGTTTAAAGCATTATTAAAGCAAGAAAAATTCAGTTCACAGAGTGAGATCGT
CACCGCACTACAAGAGCTGGGCTTTGAGAATATTAATCAGTCCAAAGTTTCTCGTATGTTGTCAAAATTCGGCGCGGTCA
GAACGCGTAATACCAAGATGGAAATGGTTTATCAGTTGCCTGCGGAATTAGGCGTGCCGACAACGTCCAGTCCGCTAAAA
AATTTAGTGGTGGATATTGATCATAATGATGTGTTGATTGTGGTAAAAACCAGCCCGGGTGCGGCACAGCTTATCGCGCG
TTTGCTTGATTCGATGGGAAAAAGCGAAGGTATTTTAGGCACGATTGCCGGTGACGATACGATTTTTATCACACCGACTA
AGGTTACTCCGGTGGAAGTTCTGATGCAGAATGTCACCGAATTATTCGAGTCTTCTTTCTAA

Upstream 100 bases:

>100_bases
AAAAAATTTTTCTAATGTTTGATTTAGATTGATTTTTTGGTATAAGTAAGCAAGAATCGGTCATAAATTAGTATTTATCA
TTAAATAAAAAAGGGCGAAA

Downstream 100 bases:

>100_bases
TGAACATTTTTCTTACCGGCGGTACCGGCTTTATCGGACAGGCTTTAGTGAAAGCATTAGTTGCGGAAGGGCATAATTTG
ACGATTTTAACTCGTCAAGC

Product: arginine repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MEKLDKLSEAFKALLKQEKFSSQSEIVTALQELGFENINQSKVSRMLSKFGAVRTRNTKMEMVYQLPAELGVPTTSSPLK
NLVVDIDHNDVLIVVKTSPGAAQLIARLLDSMGKSEGILGTIAGDDTIFITPTKVTPVEVLMQNVTELFESSF

Sequences:

>Translated_153_residues
MEKLDKLSEAFKALLKQEKFSSQSEIVTALQELGFENINQSKVSRMLSKFGAVRTRNTKMEMVYQLPAELGVPTTSSPLK
NLVVDIDHNDVLIVVKTSPGAAQLIARLLDSMGKSEGILGTIAGDDTIFITPTKVTPVEVLMQNVTELFESSF
>Mature_153_residues
MEKLDKLSEAFKALLKQEKFSSQSEIVTALQELGFENINQSKVSRMLSKFGAVRTRNTKMEMVYQLPAELGVPTTSSPLK
NLVVDIDHNDVLIVVKTSPGAAQLIARLLDSMGKSEGILGTIAGDDTIFITPTKVTPVEVLMQNVTELFESSF

Specific function: Regulates arginine biosynthesis genes

COG id: COG1438

COG function: function code K; Arginine repressor

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgR family

Homologues:

Organism=Escherichia coli, GI1789633, Length=148, Percent_Identity=75.6756756756757, Blast_Score=230, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGR_ACTP2 (A3N1U5)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053986.1
- ProteinModelPortal:   A3N1U5
- STRING:   A3N1U5
- GeneID:   4849304
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1295
- eggNOG:   COG1438
- HOGENOM:   HBG697909
- OMA:   MVYCLPN
- PhylomeDB:   A3N1U5
- ProtClustDB:   PRK05066
- BioCyc:   APLE416269:APL_1295-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00173
- InterPro:   IPR001669
- InterPro:   IPR020899
- InterPro:   IPR020900
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.30.1360.40
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR01467
- ProDom:   PD007402
- TIGRFAMs:   TIGR01529

Pfam domain/function: PF01316 Arg_repressor; PF02863 Arg_repressor_C; SSF55252 Arg_repress

EC number: NA

Molecular weight: Translated: 16790; Mature: 16790

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLDKLSEAFKALLKQEKFSSQSEIVTALQELGFENINQSKVSRMLSKFGAVRTRNTKM
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHH
EMVYQLPAELGVPTTSSPLKNLVVDIDHNDVLIVVKTSPGAAQLIARLLDSMGKSEGILG
HHHHHHHHHHCCCCCCCCHHHHEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEE
TIAGDDTIFITPTKVTPVEVLMQNVTELFESSF
EECCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKLDKLSEAFKALLKQEKFSSQSEIVTALQELGFENINQSKVSRMLSKFGAVRTRNTKM
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHH
EMVYQLPAELGVPTTSSPLKNLVVDIDHNDVLIVVKTSPGAAQLIARLLDSMGKSEGILG
HHHHHHHHHHCCCCCCCCHHHHEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEE
TIAGDDTIFITPTKVTPVEVLMQNVTELFESSF
EECCCCEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA