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The map label for this gene is ybbO [H]

Identifier: 126208732

GI number: 126208732

Start: 1455233

End: 1456054

Strand: Reverse

Name: ybbO [H]

Synonym: APL_1266

Alternate gene names: 126208732

Gene position: 1456054-1455233 (Counterclockwise)

Preceding gene: 126208733

Following gene: 126208728

Centisome position: 64.02

GC content: 44.4

Gene sequence:

>822_bases
ATGAAGACGATTCTAATTACCGGTTGTTCTTCCGGTATCGGTTATGCGACCGCCAAATTATTGAAAGAAAACGGCTGGCG
AGTGATTGCCAGTTGCAGAAAATCGGCGGATATCGACCGCTTGCAATCGGAAGGCTTCGAATGCATTCGGCTTGACGTGC
AAGATTCGGCACAAATTGCCCAAGCCTTTGAATATATAAAAGCAAGCGGTGGCTTGGATGCAGTATTTTGCAATGCAGGG
CAAGGACAGCCGGGTTGCGTGGAAGATTTACCGCGAGAAGCGTTACGTGAATTATTCGAAATCAATGTATTCGGTGTGTG
GGAAGTGATGAATCATGCACTTAAAATTTTCCGCGCCCAAAATCACGGACGTATTTTACTCACCAGCAGTATTCTAGGCT
TTGCCGCAATGCACTTTCGAGGGGCTTATAATGCGACTAAATTTGCGGTGGAAGGCATGGCGGATACGCTGCGTCACGAA
TTACACGGCTCGAATATTTATGTTAGTTTGATTGAACCGGGCCCGATTTTAAGCGATTTCCGTTCTAATTCTTTGGATAA
ACTTAATAAATATATTAATGTGGAACATACCGCTAAAACGGCATTTAACCAAAAACAATATCAGCGTTTGGCAACTAAAA
AGAATGATAACCCGTTTGCTAAACCGGCATCAGCGGTGGCGGAAGCTTGTCTAAAAGCCTTAAGCGATAGCAAACCGAAA
GCCCGTTATCAAGTCACATTCCCAACTAAACTGTTTTGGTGGCTAAGACGTATTTTACCGACTACATGGTTCGATTTTGT
GTGCCGTAAGTCCGGTGGCTAA

Upstream 100 bases:

>100_bases
GAAAGAAGACGACGGTATTTCGTTGGCACGAGAAGCGGAAGAAACGGAAGGCTTTGTGAGCGTGATTCGCTAACGATTGC
AGGGCGTATTAGAGGAAAGT

Downstream 100 bases:

>100_bases
TAGCATTATAAAACCATGGAATACACGGATTACACCGAATAATATTTCCGTGTATTCCGTGGTTAGTTTTTGCAGAATTT
GACCGCTTGTTTATAAGCTA

Product: putative dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKTILITGCSSGIGYATAKLLKENGWRVIASCRKSADIDRLQSEGFECIRLDVQDSAQIAQAFEYIKASGGLDAVFCNAG
QGQPGCVEDLPREALRELFEINVFGVWEVMNHALKIFRAQNHGRILLTSSILGFAAMHFRGAYNATKFAVEGMADTLRHE
LHGSNIYVSLIEPGPILSDFRSNSLDKLNKYINVEHTAKTAFNQKQYQRLATKKNDNPFAKPASAVAEACLKALSDSKPK
ARYQVTFPTKLFWWLRRILPTTWFDFVCRKSGG

Sequences:

>Translated_273_residues
MKTILITGCSSGIGYATAKLLKENGWRVIASCRKSADIDRLQSEGFECIRLDVQDSAQIAQAFEYIKASGGLDAVFCNAG
QGQPGCVEDLPREALRELFEINVFGVWEVMNHALKIFRAQNHGRILLTSSILGFAAMHFRGAYNATKFAVEGMADTLRHE
LHGSNIYVSLIEPGPILSDFRSNSLDKLNKYINVEHTAKTAFNQKQYQRLATKKNDNPFAKPASAVAEACLKALSDSKPK
ARYQVTFPTKLFWWLRRILPTTWFDFVCRKSGG
>Mature_273_residues
MKTILITGCSSGIGYATAKLLKENGWRVIASCRKSADIDRLQSEGFECIRLDVQDSAQIAQAFEYIKASGGLDAVFCNAG
QGQPGCVEDLPREALRELFEINVFGVWEVMNHALKIFRAQNHGRILLTSSILGFAAMHFRGAYNATKFAVEGMADTLRHE
LHGSNIYVSLIEPGPILSDFRSNSLDKLNKYINVEHTAKTAFNQKQYQRLATKKNDNPFAKPASAVAEACLKALSDSKPK
ARYQVTFPTKLFWWLRRILPTTWFDFVCRKSGG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI223718074, Length=269, Percent_Identity=32.7137546468402, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI7657478, Length=253, Percent_Identity=28.4584980237154, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI19743808, Length=282, Percent_Identity=28.7234042553192, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI44680136, Length=274, Percent_Identity=28.1021897810219, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI44680133, Length=274, Percent_Identity=28.1021897810219, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI17738292, Length=274, Percent_Identity=28.1021897810219, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI40548397, Length=290, Percent_Identity=30, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI214010158, Length=290, Percent_Identity=30, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI214010156, Length=290, Percent_Identity=30, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI22758144, Length=290, Percent_Identity=30, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI22507405, Length=285, Percent_Identity=29.1228070175439, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI150247226, Length=280, Percent_Identity=27.8571428571429, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI50726952, Length=286, Percent_Identity=29.020979020979, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI20149619, Length=282, Percent_Identity=24.822695035461, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI119392083, Length=278, Percent_Identity=25.8992805755396, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4504503, Length=291, Percent_Identity=26.1168384879725, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=30.8900523560209, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=30.5263157894737, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7706318, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI32483357, Length=190, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI109715829, Length=201, Percent_Identity=27.363184079602, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786701, Length=275, Percent_Identity=35.2727272727273, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786812, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI87082100, Length=181, Percent_Identity=33.7016574585635, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787335, Length=184, Percent_Identity=28.804347826087, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI2367365, Length=184, Percent_Identity=30.9782608695652, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193210355, Length=285, Percent_Identity=30.1754385964912, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115534660, Length=289, Percent_Identity=27.681660899654, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=204, Percent_Identity=31.8627450980392, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563809, Length=293, Percent_Identity=23.8907849829352, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17507613, Length=292, Percent_Identity=24.6575342465753, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570069, Length=209, Percent_Identity=29.6650717703349, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=214, Percent_Identity=30.8411214953271, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322067, Length=275, Percent_Identity=28.3636363636364, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24580925, Length=234, Percent_Identity=28.6324786324786, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=189, Percent_Identity=29.1005291005291, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648944, Length=194, Percent_Identity=31.4432989690722, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21358495, Length=285, Percent_Identity=24.9122807017544, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281364494, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641388, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24663911, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30474; Mature: 30474

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTILITGCSSGIGYATAKLLKENGWRVIASCRKSADIDRLQSEGFECIRLDVQDSAQIA
CCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCEEEEEECCCHHHHH
QAFEYIKASGGLDAVFCNAGQGQPGCVEDLPREALRELFEINVFGVWEVMNHALKIFRAQ
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
NHGRILLTSSILGFAAMHFRGAYNATKFAVEGMADTLRHELHGSNIYVSLIEPGPILSDF
CCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
RSNSLDKLNKYINVEHTAKTAFNQKQYQRLATKKNDNPFAKPASAVAEACLKALSDSKPK
HCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
ARYQVTFPTKLFWWLRRILPTTWFDFVCRKSGG
CEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTILITGCSSGIGYATAKLLKENGWRVIASCRKSADIDRLQSEGFECIRLDVQDSAQIA
CCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCEEEEEECCCHHHHH
QAFEYIKASGGLDAVFCNAGQGQPGCVEDLPREALRELFEINVFGVWEVMNHALKIFRAQ
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
NHGRILLTSSILGFAAMHFRGAYNATKFAVEGMADTLRHELHGSNIYVSLIEPGPILSDF
CCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
RSNSLDKLNKYINVEHTAKTAFNQKQYQRLATKKNDNPFAKPASAVAEACLKALSDSKPK
HCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
ARYQVTFPTKLFWWLRRILPTTWFDFVCRKSGG
CEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]