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The map label for this gene is serB [H]

Identifier: 126208696

GI number: 126208696

Start: 1410957

End: 1411817

Strand: Direct

Name: serB [H]

Synonym: APL_1230

Alternate gene names: 126208696

Gene position: 1410957-1411817 (Clockwise)

Preceding gene: 126208693

Following gene: 126208697

Centisome position: 62.03

GC content: 44.37

Gene sequence:

>861_bases
ATGCCAAACACGATTTTTATCTTCGCTAAATCTCTGACAACACAACAAATCGAGCGATTTACCGCGGAAACGCAATCGGT
ATTACGCAAACAAGCGGTTTATTTAGGCTATCATCTTGCATTTTTCGATACAAATTCGACCGCTTGCGATTTACGAGCCG
AGGCGGCAAAAATCGAAGCGGATATCGCCGACCTAGCGATTACGCCGAATATAAACGAAGCCGGTTTATTAGTAATGGAT
ATGGACTCCACCGCCATCAAAATCGAATGCATTGACGAGATTGCCAAACTGGCGGGTTCCGGTGAAACCGTATCGGCAAT
TACCGCCAGCGCAATGCGCGGCGAACTGGATTTTGAGCAGAGCTTGCGTAAACGAGTCGGTACATTGGAAAATGCACCGG
AAAGCATTTTGCAAACCGTACGAGAAAAACTACCGCTGATGGACGGCTTTGAACAAATGGTGAACGAGCTAAAATCACAC
GGTTGGAAACTGGCGATTGCTTCGGGCGGTTTCGATTATTTTGCCGACTATTTAAAAGAAAAATATCAGTTGGATTATGC
GGTTGCCAATCAATTGGAAATTATCGACGGAGAATTAACCGGTGTCGTATTAGGAAAAGTGGTTGATGCACAATACAAAG
CGCAAACCTTAACCAAACTGGGCGAGCAATTTCATATTCCACAAACTCAATGGGTTGCAATTGGTGACGGGGCAAACGAT
TTACCGATGATCAAAACCGCTGCACTCGGTGTTGCGCTACACGCTAAACCAAAAGTTCAAGAACAAGCGAAATTTGTGAT
AAACTTCGGTGACTTAAGCGCATTGTGCGTTCTGCTTAATGCGAAAAATCTCTATGTATAA

Upstream 100 bases:

>100_bases
TAGATTAATTGCTAATAGCTAATAGCTAATTGATAATAGATAATTCCGAAAGCACATTATCTATGCACCATTGAAAAAAG
TCTATTAAAAAGAGAACATT

Downstream 100 bases:

>100_bases
TCCCGTCATGGCGAATAGCGATATATTCGTCGTGACTTTTAATAATAAGGAATAAAAAATGCCGTCTTTTGATATTGTTT
CTGAAATTACCATGCACGAA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPNTIFIFAKSLTTQQIERFTAETQSVLRKQAVYLGYHLAFFDTNSTACDLRAEAAKIEADIADLAITPNINEAGLLVMD
MDSTAIKIECIDEIAKLAGSGETVSAITASAMRGELDFEQSLRKRVGTLENAPESILQTVREKLPLMDGFEQMVNELKSH
GWKLAIASGGFDYFADYLKEKYQLDYAVANQLEIIDGELTGVVLGKVVDAQYKAQTLTKLGEQFHIPQTQWVAIGDGAND
LPMIKTAALGVALHAKPKVQEQAKFVINFGDLSALCVLLNAKNLYV

Sequences:

>Translated_286_residues
MPNTIFIFAKSLTTQQIERFTAETQSVLRKQAVYLGYHLAFFDTNSTACDLRAEAAKIEADIADLAITPNINEAGLLVMD
MDSTAIKIECIDEIAKLAGSGETVSAITASAMRGELDFEQSLRKRVGTLENAPESILQTVREKLPLMDGFEQMVNELKSH
GWKLAIASGGFDYFADYLKEKYQLDYAVANQLEIIDGELTGVVLGKVVDAQYKAQTLTKLGEQFHIPQTQWVAIGDGAND
LPMIKTAALGVALHAKPKVQEQAKFVINFGDLSALCVLLNAKNLYV
>Mature_285_residues
PNTIFIFAKSLTTQQIERFTAETQSVLRKQAVYLGYHLAFFDTNSTACDLRAEAAKIEADIADLAITPNINEAGLLVMDM
DSTAIKIECIDEIAKLAGSGETVSAITASAMRGELDFEQSLRKRVGTLENAPESILQTVREKLPLMDGFEQMVNELKSHG
WKLAIASGGFDYFADYLKEKYQLDYAVANQLEIIDGELTGVVLGKVVDAQYKAQTLTKLGEQFHIPQTQWVAIGDGANDL
PMIKTAALGVALHAKPKVQEQAKFVINFGDLSALCVLLNAKNLYV

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=202, Percent_Identity=27.7227722772277, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1790849, Length=283, Percent_Identity=50.1766784452297, Blast_Score=278, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=41.2621359223301, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31339; Mature: 31208

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTIFIFAKSLTTQQIERFTAETQSVLRKQAVYLGYHLAFFDTNSTACDLRAEAAKIEA
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHC
DIADLAITPNINEAGLLVMDMDSTAIKIECIDEIAKLAGSGETVSAITASAMRGELDFEQ
CHHHEEECCCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
SLRKRVGTLENAPESILQTVREKLPLMDGFEQMVNELKSHGWKLAIASGGFDYFADYLKE
HHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHH
KYQLDYAVANQLEIIDGELTGVVLGKVVDAQYKAQTLTKLGEQFHIPQTQWVAIGDGAND
HHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
LPMIKTAALGVALHAKPKVQEQAKFVINFGDLSALCVLLNAKNLYV
CCHHHHHHHCEEEECCCCHHCCCEEEEEECCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PNTIFIFAKSLTTQQIERFTAETQSVLRKQAVYLGYHLAFFDTNSTACDLRAEAAKIEA
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHC
DIADLAITPNINEAGLLVMDMDSTAIKIECIDEIAKLAGSGETVSAITASAMRGELDFEQ
CHHHEEECCCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
SLRKRVGTLENAPESILQTVREKLPLMDGFEQMVNELKSHGWKLAIASGGFDYFADYLKE
HHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHH
KYQLDYAVANQLEIIDGELTGVVLGKVVDAQYKAQTLTKLGEQFHIPQTQWVAIGDGAND
HHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
LPMIKTAALGVALHAKPKVQEQAKFVINFGDLSALCVLLNAKNLYV
CCHHHHHHHCEEEECCCCHHCCCEEEEEECCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]