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The map label for this gene is betT [C]

Identifier: 126208677

GI number: 126208677

Start: 1390767

End: 1392794

Strand: Reverse

Name: betT [C]

Synonym: APL_1209

Alternate gene names: 126208677

Gene position: 1392794-1390767 (Counterclockwise)

Preceding gene: 126208680

Following gene: 126208676

Centisome position: 61.24

GC content: 41.22

Gene sequence:

>2028_bases
ATGAAACTCACGGCATTTTTACGTGATAAATCATCATTTAATCCGTTTGTAACGAGTATCACTTTATTTATTGTTATTTT
ACTTGTTGCCTTTACTTTGCTCTTACCCGGCCAAACCCAAACGGTATTGGATTGGTTAAAAGCGACAATTTTCCAACATT
TCAGTTGGTTTTATATTTTAGTCGGATCGTTATTTTTATTTTTCTTGATTTTTGTGTCGTTGAGCAGTTTCGGCAATATC
AAGTTAGGTACGAATGAAGAAGAACCGGAATTTCACTTTATGTCTTGGATGGCAATGTTATTTGCCGCCGGAATGGGGGT
GGGATTAATGTTTTTCGGGGTTGCCGAACCGCTTTCGCATTATGTGTCCGGTATTAGTACCGGTAGTACCGAGCAGCAGG
CGCAACAAGCCTTATTACACACGGTATTTCACTGGGGAATGCACGCTTGGGCGATTTACGGTGTGATTGCACTGGCTCTC
GCTTATTTTGGCTTTCGTTATAAATTGCCACTTGCATTACGTTCTTGTTTTTATCCGCTGTTAAAAGATCGTATTAACGG
ACGTTTAGGTGATGTGATCGATATTATGGCATTGGTTGCTACGCTATTCGGTATCATTACTACACTTGGTTTTGGTGCGG
CACAGTTAGGATCAGGTTTGGTTGCGCTGGGTTGGTTAAACGAAAGCGGTTTTGGGCTGAAAATCGGTGTAATTATCACC
GTGATGACTCTTGCGATTTTGTCAGCGATTTCGGGCGTAGGAAAAGGTGTAAAAATTTTAAGCGAAACCAATTTAGGATT
AGCCGGATTCTTATTGTTATTTGTGTTAATTAGCGGTCCGACACTGTATTTATTATCGGCGTTTAGCGAGAACATCGGTA
CTTATTTTAGCCAGTTAGTTCAACTGAGTTTTAAGACTTATGCCTATGAGAGTAAGCAAACGGGATGGTTTAATGCTTGG
ACAATTCTTTATTGGGCTTGGTGGTGTTCATGGGCGCCGTTTGTCGGACTGTTTATCGCTCGAATTTCGCGCGGTAGAAC
CATTCGTGAATTTGTATTCGGCGTGTTAGCCATTCCGAGCTTATTCGGCATTTTATGGTTTACCGTATTTGGTAACAGTG
CGATTTGGCTGGATAACAATGTCGCACAGGGTATGTTATCCGGTTTGATTTCAACGCCGGAAACCTTACTGTTTAAATTC
CTTGAGTATTTACCGTTTTCAGGTTTAACCAGTTTTATTGCGTTGGTTAGTATTGCGTTATTTTTTATCACATCAGCGGA
TTCGGGGATTTATGTGCTGAACAATATTGCCTCTCGTGATAAAAGTTTAGCTTCGCCACGTTGGCAAGCGATGATGTGGG
GCATATTAATGTCAATCGTTGCTATTACTTTACTTGGCTCGGGCGGATTAGCGACCTTACAAACAATGACATTAATTACC
GCATTACCTTTTGCGATGTTGATGGTCGTTATTTGTGTCAGTTTAATGAAAGCCTTAGCGGTGGATAAAAAATATTTTGA
GGCGAAATTTAATCCGACTACGGTTTTATGGTCAGGCGAAAACTGGAAAACTCGTCTCAATCAAATGCTGAACCAGACCG
AAGACAAAGATATTTTAAAATTCTTAAAACATACCGCTTTACCGGCGATGAGAGAATTACGCCGAGAGCTCATTTCGGAA
TATGATCTGAATGTGGACGTGATCACTAAATTCGATGAAGTCGAACCGGCGGTCGAGTTTGTGATTCATACCGAGTCGCT
ACAAGATTTTATGTATGGGATTCGTTCGGTCGGCCATCAAGTTTCCGAGCAATTAATCAATGACGAACATTTACCGCATA
TTCAGAATGAAACGACTTACGAGCCGCTAAGCTATTTCTTTGACGGTCGTAACGGCTACGATGTGCAATATATGACGCAT
AATGAAATCATTGCCGATATTCTGAAACATTATGAGCGTTATCTCAGCTTGTTACGCGATGTCGGTCAAGAGTTAATGTC
ACATGAACCGACCGAATTGGCGGAGTAG

Upstream 100 bases:

>100_bases
GTCAATTAAGGGTGTCTGTGCCTTTTCTTTCGGTTCCGTTCGAACCTTCTTCATCTGTTATAGAACACTATTTTAATCTT
AAATCGACAAAGGAGTATTT

Downstream 100 bases:

>100_bases
AGCGGTAAACGTAAGCGGTCAAATTTACTGATTTTTTAGCAAGTTTAGACATCATTTACAGTTATAATCCTTATAAGAAA
AGATGATTATATTTTATATC

Product: putative choline-glycine betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MKLTAFLRDKSSFNPFVTSITLFIVILLVAFTLLLPGQTQTVLDWLKATIFQHFSWFYILVGSLFLFFLIFVSLSSFGNI
KLGTNEEEPEFHFMSWMAMLFAAGMGVGLMFFGVAEPLSHYVSGISTGSTEQQAQQALLHTVFHWGMHAWAIYGVIALAL
AYFGFRYKLPLALRSCFYPLLKDRINGRLGDVIDIMALVATLFGIITTLGFGAAQLGSGLVALGWLNESGFGLKIGVIIT
VMTLAILSAISGVGKGVKILSETNLGLAGFLLLFVLISGPTLYLLSAFSENIGTYFSQLVQLSFKTYAYESKQTGWFNAW
TILYWAWWCSWAPFVGLFIARISRGRTIREFVFGVLAIPSLFGILWFTVFGNSAIWLDNNVAQGMLSGLISTPETLLFKF
LEYLPFSGLTSFIALVSIALFFITSADSGIYVLNNIASRDKSLASPRWQAMMWGILMSIVAITLLGSGGLATLQTMTLIT
ALPFAMLMVVICVSLMKALAVDKKYFEAKFNPTTVLWSGENWKTRLNQMLNQTEDKDILKFLKHTALPAMRELRRELISE
YDLNVDVITKFDEVEPAVEFVIHTESLQDFMYGIRSVGHQVSEQLINDEHLPHIQNETTYEPLSYFFDGRNGYDVQYMTH
NEIIADILKHYERYLSLLRDVGQELMSHEPTELAE

Sequences:

>Translated_675_residues
MKLTAFLRDKSSFNPFVTSITLFIVILLVAFTLLLPGQTQTVLDWLKATIFQHFSWFYILVGSLFLFFLIFVSLSSFGNI
KLGTNEEEPEFHFMSWMAMLFAAGMGVGLMFFGVAEPLSHYVSGISTGSTEQQAQQALLHTVFHWGMHAWAIYGVIALAL
AYFGFRYKLPLALRSCFYPLLKDRINGRLGDVIDIMALVATLFGIITTLGFGAAQLGSGLVALGWLNESGFGLKIGVIIT
VMTLAILSAISGVGKGVKILSETNLGLAGFLLLFVLISGPTLYLLSAFSENIGTYFSQLVQLSFKTYAYESKQTGWFNAW
TILYWAWWCSWAPFVGLFIARISRGRTIREFVFGVLAIPSLFGILWFTVFGNSAIWLDNNVAQGMLSGLISTPETLLFKF
LEYLPFSGLTSFIALVSIALFFITSADSGIYVLNNIASRDKSLASPRWQAMMWGILMSIVAITLLGSGGLATLQTMTLIT
ALPFAMLMVVICVSLMKALAVDKKYFEAKFNPTTVLWSGENWKTRLNQMLNQTEDKDILKFLKHTALPAMRELRRELISE
YDLNVDVITKFDEVEPAVEFVIHTESLQDFMYGIRSVGHQVSEQLINDEHLPHIQNETTYEPLSYFFDGRNGYDVQYMTH
NEIIADILKHYERYLSLLRDVGQELMSHEPTELAE
>Mature_675_residues
MKLTAFLRDKSSFNPFVTSITLFIVILLVAFTLLLPGQTQTVLDWLKATIFQHFSWFYILVGSLFLFFLIFVSLSSFGNI
KLGTNEEEPEFHFMSWMAMLFAAGMGVGLMFFGVAEPLSHYVSGISTGSTEQQAQQALLHTVFHWGMHAWAIYGVIALAL
AYFGFRYKLPLALRSCFYPLLKDRINGRLGDVIDIMALVATLFGIITTLGFGAAQLGSGLVALGWLNESGFGLKIGVIIT
VMTLAILSAISGVGKGVKILSETNLGLAGFLLLFVLISGPTLYLLSAFSENIGTYFSQLVQLSFKTYAYESKQTGWFNAW
TILYWAWWCSWAPFVGLFIARISRGRTIREFVFGVLAIPSLFGILWFTVFGNSAIWLDNNVAQGMLSGLISTPETLLFKF
LEYLPFSGLTSFIALVSIALFFITSADSGIYVLNNIASRDKSLASPRWQAMMWGILMSIVAITLLGSGGLATLQTMTLIT
ALPFAMLMVVICVSLMKALAVDKKYFEAKFNPTTVLWSGENWKTRLNQMLNQTEDKDILKFLKHTALPAMRELRRELISE
YDLNVDVITKFDEVEPAVEFVIHTESLQDFMYGIRSVGHQVSEQLINDEHLPHIQNETTYEPLSYFFDGRNGYDVQYMTH
NEIIADILKHYERYLSLLRDVGQELMSHEPTELAE

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=673, Percent_Identity=35.2154531946508, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1788102, Length=450, Percent_Identity=29.7777777777778, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1786224, Length=513, Percent_Identity=28.0701754385965, Blast_Score=153, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 75706; Mature: 75706

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTAFLRDKSSFNPFVTSITLFIVILLVAFTLLLPGQTQTVLDWLKATIFQHFSWFYIL
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VGSLFLFFLIFVSLSSFGNIKLGTNEEEPEFHFMSWMAMLFAAGMGVGLMFFGVAEPLSH
HHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSGISTGSTEQQAQQALLHTVFHWGMHAWAIYGVIALALAYFGFRYKLPLALRSCFYPL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDRINGRLGDVIDIMALVATLFGIITTLGFGAAQLGSGLVALGWLNESGFGLKIGVIIT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCHHHHHHH
VMTLAILSAISGVGKGVKILSETNLGLAGFLLLFVLISGPTLYLLSAFSENIGTYFSQLV
HHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QLSFKTYAYESKQTGWFNAWTILYWAWWCSWAPFVGLFIARISRGRTIREFVFGVLAIPS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LFGILWFTVFGNSAIWLDNNVAQGMLSGLISTPETLLFKFLEYLPFSGLTSFIALVSIAL
HHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FFITSADSGIYVLNNIASRDKSLASPRWQAMMWGILMSIVAITLLGSGGLATLQTMTLIT
HHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALPFAMLMVVICVSLMKALAVDKKYFEAKFNPTTVLWSGENWKTRLNQMLNQTEDKDILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHH
FLKHTALPAMRELRRELISEYDLNVDVITKFDEVEPAVEFVIHTESLQDFMYGIRSVGHQ
HHHHHCCHHHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSEQLINDEHLPHIQNETTYEPLSYFFDGRNGYDVQYMTHNEIIADILKHYERYLSLLRD
HHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
VGQELMSHEPTELAE
HHHHHHCCCCHHCCC
>Mature Secondary Structure
MKLTAFLRDKSSFNPFVTSITLFIVILLVAFTLLLPGQTQTVLDWLKATIFQHFSWFYIL
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VGSLFLFFLIFVSLSSFGNIKLGTNEEEPEFHFMSWMAMLFAAGMGVGLMFFGVAEPLSH
HHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSGISTGSTEQQAQQALLHTVFHWGMHAWAIYGVIALALAYFGFRYKLPLALRSCFYPL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDRINGRLGDVIDIMALVATLFGIITTLGFGAAQLGSGLVALGWLNESGFGLKIGVIIT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCHHHHHHH
VMTLAILSAISGVGKGVKILSETNLGLAGFLLLFVLISGPTLYLLSAFSENIGTYFSQLV
HHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QLSFKTYAYESKQTGWFNAWTILYWAWWCSWAPFVGLFIARISRGRTIREFVFGVLAIPS
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LFGILWFTVFGNSAIWLDNNVAQGMLSGLISTPETLLFKFLEYLPFSGLTSFIALVSIAL
HHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FFITSADSGIYVLNNIASRDKSLASPRWQAMMWGILMSIVAITLLGSGGLATLQTMTLIT
HHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALPFAMLMVVICVSLMKALAVDKKYFEAKFNPTTVLWSGENWKTRLNQMLNQTEDKDILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHH
FLKHTALPAMRELRRELISEYDLNVDVITKFDEVEPAVEFVIHTESLQDFMYGIRSVGHQ
HHHHHCCHHHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSEQLINDEHLPHIQNETTYEPLSYFFDGRNGYDVQYMTHNEIIADILKHYERYLSLLRD
HHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
VGQELMSHEPTELAE
HHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]