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The map label for this gene is hsdM [C]

Identifier: 126208662

GI number: 126208662

Start: 1373145

End: 1374797

Strand: Reverse

Name: hsdM [C]

Synonym: APL_1194

Alternate gene names: 126208662

Gene position: 1374797-1373145 (Counterclockwise)

Preceding gene: 126208663

Following gene: 126208661

Centisome position: 60.44

GC content: 43.44

Gene sequence:

>1653_bases
ATGACCGAACAACTTTTTCAACAAAAAACTAAAGAATTGATCGACAGCTTAAAAGCCATTTGTGCGAACTATGGGCTAGG
GAATGATGGCAATGAATTTAAAATCATTACCCAAGTATTTTTGTATAAATTTCTTAATGACAAATTTGCCTTTGAAATCA
AGCAGATTAAACCGTCTTTGGCGGAGCATGATAGCTGGGAGCAAGCGTTGGGTGAAATGTCCGCTGAAGATTTTGACTTT
TTAACAATGAATATGAACGGCGACACCGCCATTTTGCGACCAAATCAATTTATCAGCCATTTGTTCAACCAATCGAACAT
CGCCAACTTTGCCAATTTGTTTGATGAAACCCTAATGGACATCGCCGCTCAAAATGCGGATATTTTCTCAGTAAAAACCG
AAGGTGGGGCGAAAATCAACTTGTTTGACCGTGTCAGCCAATATATTGCCGACCCCAGCAAGCGAGACGCATTCTGCCGT
GCGGTCATCAACAAATTGGTGGAATTTAGTTTCGAGCATATTTTCAACCAAAAATTTGATTTTTACGCCACGATTTTTGA
GTATCTCATCAAAGATTACAACACCAACTCGGGCGGAAAATATGCCGAATACTACACGCCACACGCGGTGGCTCGTATTA
TGGCGGCAATTCTCGTGCCTGAAAACGTGCGCGGGCAGTTGCAAAATGTCAGCTGTTACGATCCGTCCGCAGGCTCTGGC
ACATTGTTGATGAACATCGCCCATGCCATCGGCGAAAAAAAATGTACCATTTACACACAGGATATTTCGCAAAAATCGTC
AAACTTGTTGCGATTAAATCTGATCTTAAACAATCTTGTCGCCAGTATTCCCAATGTGGTGCAAGGGAATACGATGACAC
ACCCTTACCACAAATCGGGCGATCAACTCCGCCAGTTTGATTACATCGTGTCTAACCCACCGTTCAAAATGGATTTCAGC
GAAGTGCGAGAGGAATTAGCCGAAACCGCTCACAAAGCCCGCTTTTTTGCTGGCGTGCCAAACGTGCCAAAAGCCAAAAA
AGAGGGAATGAAAATTTATTTACTTTTTGTTCAGCACATCATTCATTCGCTCAAAGCAGACGGCAAGGCTGCGGTGGTGT
TGCCAACGGGCTTTATTACCGATCAATCGAAGATTGATAAGAAAATCCGAGAATTTCTAGTAAACGAAAAAATGTTAGCG
GGCGTGGTGTCGATGCCGTCTAACATTTTCGCCACCACAGGCACGAACGTCTCTATTCTCTTTCTCGACCGAGCCAACCA
AGAGAACGTGGTGCTGATTGATGCCAGCAACTTGGGTGAAAAAATCAAAGAGGGCAAAAACCAAAAAACCGTGCTTTCCG
CCGAAGAAGAGCAACGCATTATTGACGTGTTCAACCAGAAAAAAGCGGAAGAAGATTTCTCGGTAGTAGTCTCTTATGCC
AACATCGAAGCCAAAAATTATAGCCTATCCGCAGGGCAGTACTTTGATGTGAAAACCGACCATATCGACATCACCGCTGC
CGAGTTTGAGCAGAAAATGGCAGATTTTCAGCAAAATCTGACCGCACTTTTTGCCGAAAGCAAGGCGTTAGAAAGCCAAA
TTCAGCAACAAATGGCAACATTAAAATTTAACGCACAAGTGGTGGAAAATTAG

Upstream 100 bases:

>100_bases
CGTTAATCGAAATGACGATTCCTGATAAAACAACGAGTCCTAACCAAAAATATCGCTTAACTGAAAAAGGTAAACAATTT
TTAATAAAAGGCACACTAAA

Downstream 100 bases:

>100_bases
GGGAAGTTTGCGAGATGGTAGTTAATTATATTAAGTTTAACGATACTGAAATTGAATTTATTGATGGTGATCGAGGCATT
CATTATCCTAAAAAAGAAGA

Product: type I restriction-modification system, M subunit

Products: NA

Alternate protein names: M.MpnORFDP [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTEQLFQQKTKELIDSLKAICANYGLGNDGNEFKIITQVFLYKFLNDKFAFEIKQIKPSLAEHDSWEQALGEMSAEDFDF
LTMNMNGDTAILRPNQFISHLFNQSNIANFANLFDETLMDIAAQNADIFSVKTEGGAKINLFDRVSQYIADPSKRDAFCR
AVINKLVEFSFEHIFNQKFDFYATIFEYLIKDYNTNSGGKYAEYYTPHAVARIMAAILVPENVRGQLQNVSCYDPSAGSG
TLLMNIAHAIGEKKCTIYTQDISQKSSNLLRLNLILNNLVASIPNVVQGNTMTHPYHKSGDQLRQFDYIVSNPPFKMDFS
EVREELAETAHKARFFAGVPNVPKAKKEGMKIYLLFVQHIIHSLKADGKAAVVLPTGFITDQSKIDKKIREFLVNEKMLA
GVVSMPSNIFATTGTNVSILFLDRANQENVVLIDASNLGEKIKEGKNQKTVLSAEEEQRIIDVFNQKKAEEDFSVVVSYA
NIEAKNYSLSAGQYFDVKTDHIDITAAEFEQKMADFQQNLTALFAESKALESQIQQQMATLKFNAQVVEN

Sequences:

>Translated_550_residues
MTEQLFQQKTKELIDSLKAICANYGLGNDGNEFKIITQVFLYKFLNDKFAFEIKQIKPSLAEHDSWEQALGEMSAEDFDF
LTMNMNGDTAILRPNQFISHLFNQSNIANFANLFDETLMDIAAQNADIFSVKTEGGAKINLFDRVSQYIADPSKRDAFCR
AVINKLVEFSFEHIFNQKFDFYATIFEYLIKDYNTNSGGKYAEYYTPHAVARIMAAILVPENVRGQLQNVSCYDPSAGSG
TLLMNIAHAIGEKKCTIYTQDISQKSSNLLRLNLILNNLVASIPNVVQGNTMTHPYHKSGDQLRQFDYIVSNPPFKMDFS
EVREELAETAHKARFFAGVPNVPKAKKEGMKIYLLFVQHIIHSLKADGKAAVVLPTGFITDQSKIDKKIREFLVNEKMLA
GVVSMPSNIFATTGTNVSILFLDRANQENVVLIDASNLGEKIKEGKNQKTVLSAEEEQRIIDVFNQKKAEEDFSVVVSYA
NIEAKNYSLSAGQYFDVKTDHIDITAAEFEQKMADFQQNLTALFAESKALESQIQQQMATLKFNAQVVEN
>Mature_549_residues
TEQLFQQKTKELIDSLKAICANYGLGNDGNEFKIITQVFLYKFLNDKFAFEIKQIKPSLAEHDSWEQALGEMSAEDFDFL
TMNMNGDTAILRPNQFISHLFNQSNIANFANLFDETLMDIAAQNADIFSVKTEGGAKINLFDRVSQYIADPSKRDAFCRA
VINKLVEFSFEHIFNQKFDFYATIFEYLIKDYNTNSGGKYAEYYTPHAVARIMAAILVPENVRGQLQNVSCYDPSAGSGT
LLMNIAHAIGEKKCTIYTQDISQKSSNLLRLNLILNNLVASIPNVVQGNTMTHPYHKSGDQLRQFDYIVSNPPFKMDFSE
VREELAETAHKARFFAGVPNVPKAKKEGMKIYLLFVQHIIHSLKADGKAAVVLPTGFITDQSKIDKKIREFLVNEKMLAG
VVSMPSNIFATTGTNVSILFLDRANQENVVLIDASNLGEKIKEGKNQKTVLSAEEEQRIIDVFNQKKAEEDFSVVVSYAN
IEAKNYSLSAGQYFDVKTDHIDITAAEFEQKMADFQQNLTALFAESKALESQIQQQMATLKFNAQVVEN

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 61941; Mature: 61810

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQLFQQKTKELIDSLKAICANYGLGNDGNEFKIITQVFLYKFLNDKFAFEIKQIKPSL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHEEHHHHHCCHH
AEHDSWEQALGEMSAEDFDFLTMNMNGDTAILRPNQFISHLFNQSNIANFANLFDETLMD
HCCCCHHHHHHCCCCCCCCEEEEECCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHH
IAAQNADIFSVKTEGGAKINLFDRVSQYIADPSKRDAFCRAVINKLVEFSFEHIFNQKFD
HHHCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
FYATIFEYLIKDYNTNSGGKYAEYYTPHAVARIMAAILVPENVRGQLQNVSCYDPSAGSG
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCEEECCCCCCC
TLLMNIAHAIGEKKCTIYTQDISQKSSNLLRLNLILNNLVASIPNVVQGNTMTHPYHKSG
HHHHHHHHHHCCCCEEEEECCHHCCCCCEEEHHHHHHHHHHHCCHHHCCCCCCCCCCCCC
DQLRQFDYIVSNPPFKMDFSEVREELAETAHKARFFAGVPNVPKAKKEGMKIYLLFVQHI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEHHHHHHHH
IHSLKADGKAAVVLPTGFITDQSKIDKKIREFLVNEKMLAGVVSMPSNIFATTGTNVSIL
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCEEEE
FLDRANQENVVLIDASNLGEKIKEGKNQKTVLSAEEEQRIIDVFNQKKAEEDFSVVVSYA
EEECCCCCCEEEEECHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCCCHHEEEEEE
NIEAKNYSLSAGQYFDVKTDHIDITAAEFEQKMADFQQNLTALFAESKALESQIQQQMAT
EEEECCEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKFNAQVVEN
HHCCEEEECC
>Mature Secondary Structure 
TEQLFQQKTKELIDSLKAICANYGLGNDGNEFKIITQVFLYKFLNDKFAFEIKQIKPSL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHEEHHHHHCCHH
AEHDSWEQALGEMSAEDFDFLTMNMNGDTAILRPNQFISHLFNQSNIANFANLFDETLMD
HCCCCHHHHHHCCCCCCCCEEEEECCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHH
IAAQNADIFSVKTEGGAKINLFDRVSQYIADPSKRDAFCRAVINKLVEFSFEHIFNQKFD
HHHCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
FYATIFEYLIKDYNTNSGGKYAEYYTPHAVARIMAAILVPENVRGQLQNVSCYDPSAGSG
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCEEECCCCCCC
TLLMNIAHAIGEKKCTIYTQDISQKSSNLLRLNLILNNLVASIPNVVQGNTMTHPYHKSG
HHHHHHHHHHCCCCEEEEECCHHCCCCCEEEHHHHHHHHHHHCCHHHCCCCCCCCCCCCC
DQLRQFDYIVSNPPFKMDFSEVREELAETAHKARFFAGVPNVPKAKKEGMKIYLLFVQHI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEHHHHHHHH
IHSLKADGKAAVVLPTGFITDQSKIDKKIREFLVNEKMLAGVVSMPSNIFATTGTNVSIL
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECCCCEEEE
FLDRANQENVVLIDASNLGEKIKEGKNQKTVLSAEEEQRIIDVFNQKKAEEDFSVVVSYA
EEECCCCCCEEEEECHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCCCHHEEEEEE
NIEAKNYSLSAGQYFDVKTDHIDITAAEFEQKMADFQQNLTALFAESKALESQIQQQMAT
EEEECCEEECCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKFNAQVVEN
HHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]