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The map label for this gene is trpD

Identifier: 126208633

GI number: 126208633

Start: 1342456

End: 1343460

Strand: Direct

Name: trpD

Synonym: APL_1165

Alternate gene names: 126208633

Gene position: 1342456-1343460 (Clockwise)

Preceding gene: 126208632

Following gene: 126208634

Centisome position: 59.02

GC content: 44.38

Gene sequence:

>1005_bases
ATGCAACTCGACAACATTCTTAGCCAATTATTTGAGAACCAAGCGCTCACAAAAGCAGAATCGCAATACTTTTTTGAACA
AGTAATTCAAGGTAATGTTTCTAACGAACAACTCGCCGGCGCATTAATTGCGTTAAAAGTACGGGGCGAGACAATTGAGG
AAATTGCCGGAGCGGTTGAAGCGGCATTTGCAAATGCAACTACATTCCCAACTCCCGATTACGATTTTGCCGATATTGTC
GGAACCGGTGGCGACGGGCAAAATACAATTAATATTTCTACCGCCAGTGCGATTGTAGCGGCGACTTTAGGTTACAAAGT
CGCAAAACACGGTAGTCGCAGCGTTTCCAGTAAAACCGGCGCAAGCGATGTGCTATCCGCATTAGGGATTAATGTGGCGA
TTTCCCCCCAAACCGCACGCCAAGCGTTAGATGAAAATAATCTCTGTTTCTTATTTGCTCCGCTTTATCACGCCGGTTTT
AAACACGCCGTACCGGTGCGACAAACGTTGAAAACTCGCACGCTATTTAACATTTTAGGACCGTTGGTCAATCCGGCACA
CGCTAAACGCCAATTACTCGGCGTTTATTCACCGGAAGTTTTGAAAATTTATGCAGAAACGGTACGCACCTTAAATCATC
AACATTCGATTGTGGTGTACGGTTCCGGTTTAGATGAAGTGGCTGTACACGGCGAAACTTTAGTCGCTGAAATTGAAGAT
GACAAAATTCACTATTTCAGCCTCATACCGGAGGATTTTGGGGTTCAACGCCATTCGATTGAAGCTTTAAGAGGTGGAGA
ACCTACAGAAAATGCGGAAAAAATTACCGTTTTATTACAAGGCAAAGGCGAAGCGGCACATATTGATGCGGTAGCGGTAA
ATACTGCAATGCTTATGCGTACTTTCGGCGAACGAAATTTAAAAGCCAACGTACAACGTGTCAAAGATTTGCTCAGAACA
GATAAAGCCTACCAGACCTTGCAAAAGCTCGCCCAATATCAGTAA

Upstream 100 bases:

>100_bases
TATTAAAACAATCGGTCGAATGGCTGCTTTCCACACAACATTAAGCAAAAAAATTTAGAAAAATAACCGCTTATCAGTAT
AACGAAAACAGGATAACACT

Downstream 100 bases:

>100_bases
CATATCGCCCACATTTGTGGGCTTTTTTATAGGAATAAACAGTTGAAAAAAAGTATTTACGATACCCCGATTTTCTTTGA
ACGTTATCAACAATTACGTG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MQLDNILSQLFENQALTKAESQYFFEQVIQGNVSNEQLAGALIALKVRGETIEEIAGAVEAAFANATTFPTPDYDFADIV
GTGGDGQNTINISTASAIVAATLGYKVAKHGSRSVSSKTGASDVLSALGINVAISPQTARQALDENNLCFLFAPLYHAGF
KHAVPVRQTLKTRTLFNILGPLVNPAHAKRQLLGVYSPEVLKIYAETVRTLNHQHSIVVYGSGLDEVAVHGETLVAEIED
DKIHYFSLIPEDFGVQRHSIEALRGGEPTENAEKITVLLQGKGEAAHIDAVAVNTAMLMRTFGERNLKANVQRVKDLLRT
DKAYQTLQKLAQYQ

Sequences:

>Translated_334_residues
MQLDNILSQLFENQALTKAESQYFFEQVIQGNVSNEQLAGALIALKVRGETIEEIAGAVEAAFANATTFPTPDYDFADIV
GTGGDGQNTINISTASAIVAATLGYKVAKHGSRSVSSKTGASDVLSALGINVAISPQTARQALDENNLCFLFAPLYHAGF
KHAVPVRQTLKTRTLFNILGPLVNPAHAKRQLLGVYSPEVLKIYAETVRTLNHQHSIVVYGSGLDEVAVHGETLVAEIED
DKIHYFSLIPEDFGVQRHSIEALRGGEPTENAEKITVLLQGKGEAAHIDAVAVNTAMLMRTFGERNLKANVQRVKDLLRT
DKAYQTLQKLAQYQ
>Mature_334_residues
MQLDNILSQLFENQALTKAESQYFFEQVIQGNVSNEQLAGALIALKVRGETIEEIAGAVEAAFANATTFPTPDYDFADIV
GTGGDGQNTINISTASAIVAATLGYKVAKHGSRSVSSKTGASDVLSALGINVAISPQTARQALDENNLCFLFAPLYHAGF
KHAVPVRQTLKTRTLFNILGPLVNPAHAKRQLLGVYSPEVLKIYAETVRTLNHQHSIVVYGSGLDEVAVHGETLVAEIED
DKIHYFSLIPEDFGVQRHSIEALRGGEPTENAEKITVLLQGKGEAAHIDAVAVNTAMLMRTFGERNLKANVQRVKDLLRT
DKAYQTLQKLAQYQ

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=329, Percent_Identity=56.2310030395137, Blast_Score=343, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6320561, Length=321, Percent_Identity=33.6448598130841, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_ACTP2 (A3N1G7)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053858.1
- ProteinModelPortal:   A3N1G7
- SMR:   A3N1G7
- STRING:   A3N1G7
- GeneID:   4849521
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1165
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   A3N1G7
- ProtClustDB:   PRK00188
- BioCyc:   APLE416269:APL_1165-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36243; Mature: 36243

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLDNILSQLFENQALTKAESQYFFEQVIQGNVSNEQLAGALIALKVRGETIEEIAGAVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCEEEEEEECCCHHHHHHHHHH
AAFANATTFPTPDYDFADIVGTGGDGQNTINISTASAIVAATLGYKVAKHGSRSVSSKTG
HHHCCCCCCCCCCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCC
ASDVLSALGINVAISPQTARQALDENNLCFLFAPLYHAGFKHAVPVRQTLKTRTLFNILG
HHHHHHHHCCCEEECCHHHHHHCCCCCEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHH
PLVNPAHAKRQLLGVYSPEVLKIYAETVRTLNHQHSIVVYGSGLDEVAVHGETLVAEIED
HHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCEEEEEECC
DKIHYFSLIPEDFGVQRHSIEALRGGEPTENAEKITVLLQGKGEAAHIDAVAVNTAMLMR
CCEEEEEECCHHHCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHH
TFGERNLKANVQRVKDLLRTDKAYQTLQKLAQYQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLDNILSQLFENQALTKAESQYFFEQVIQGNVSNEQLAGALIALKVRGETIEEIAGAVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCEEEEEEECCCHHHHHHHHHH
AAFANATTFPTPDYDFADIVGTGGDGQNTINISTASAIVAATLGYKVAKHGSRSVSSKTG
HHHCCCCCCCCCCCCHHHHEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCC
ASDVLSALGINVAISPQTARQALDENNLCFLFAPLYHAGFKHAVPVRQTLKTRTLFNILG
HHHHHHHHCCCEEECCHHHHHHCCCCCEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHH
PLVNPAHAKRQLLGVYSPEVLKIYAETVRTLNHQHSIVVYGSGLDEVAVHGETLVAEIED
HHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCEEEEEECC
DKIHYFSLIPEDFGVQRHSIEALRGGEPTENAEKITVLLQGKGEAAHIDAVAVNTAMLMR
CCEEEEEECCHHHCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHH
TFGERNLKANVQRVKDLLRTDKAYQTLQKLAQYQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA