Click here to switch to the map view.

The map label for this gene is orn

Identifier: 126208604

GI number: 126208604

Start: 1310991

End: 1311545

Strand: Direct

Name: orn

Synonym: APL_1134

Alternate gene names: 126208604

Gene position: 1310991-1311545 (Clockwise)

Preceding gene: 126208603

Following gene: 126208605

Centisome position: 57.64

GC content: 37.12

Gene sequence:

>555_bases
ATGAGTAAATTAGATAACCAAAATCTTATATGGATTGATTTGGAAATGACCGGACTTGATCCGGAAAAAGAGCGTATTAT
CGAAGTTGCGACGATTGTAACGGATAAAGATTTAAATATTTTAGCCGAAGGTCCGGTATTAACCGTTCATCAATCGAACG
ATTTGCTTAATAAAATGAGTGATTGGTGCATTAAAACGCATACGGAAAACGGCTTAATCGAACGCGTAAAACAAAGTAAA
TTAACCGAACGTGCGGTCGAATTACAAACCATCGATTTTTTAAAACAGTGGGTGCCGAAAGGTGCTTCGCCGATTTGCGG
TAACAGCGTAGCGCAAGATAAGCGTTTCTTGTATAAATATATGCCGGATCTTGCCGATTATTTTCATTATCGCCATTTGG
ATGTGAGTACTTTAAAAGAACTTGCGCGCCGTTGGAAACCGGATATGCTGAATGCCTTCAACAAAAAAAATACGCATTTG
GCTTTAGATGATATTCGAGAATCGATCGAAGAATTAAAATTTTACCGTACCCATTTTATTAATTTAGAGAAATAA

Upstream 100 bases:

>100_bases
TATCCTCGACAATGGTACGTGAAATTTATCGCCATCAAGGCGATGTGGCGCAATTTGTGCCTAATGCGGTACTTTGCGCC
TTAAAAGAAAAGGAATAAAT

Downstream 100 bases:

>100_bases
CCGTCCGATGTCCGATTTAGTTACTTTTTATTTTCCCGATGAAAACCGAATGTTGCAATTCGGGCAACAATTTGCCAACG
CAATAAGAACATACCTTGAA

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSKLDNQNLIWIDLEMTGLDPEKERIIEVATIVTDKDLNILAEGPVLTVHQSNDLLNKMSDWCIKTHTENGLIERVKQSK
LTERAVELQTIDFLKQWVPKGASPICGNSVAQDKRFLYKYMPDLADYFHYRHLDVSTLKELARRWKPDMLNAFNKKNTHL
ALDDIRESIEELKFYRTHFINLEK

Sequences:

>Translated_184_residues
MSKLDNQNLIWIDLEMTGLDPEKERIIEVATIVTDKDLNILAEGPVLTVHQSNDLLNKMSDWCIKTHTENGLIERVKQSK
LTERAVELQTIDFLKQWVPKGASPICGNSVAQDKRFLYKYMPDLADYFHYRHLDVSTLKELARRWKPDMLNAFNKKNTHL
ALDDIRESIEELKFYRTHFINLEK
>Mature_183_residues
SKLDNQNLIWIDLEMTGLDPEKERIIEVATIVTDKDLNILAEGPVLTVHQSNDLLNKMSDWCIKTHTENGLIERVKQSKL
TERAVELQTIDFLKQWVPKGASPICGNSVAQDKRFLYKYMPDLADYFHYRHLDVSTLKELARRWKPDMLNAFNKKNTHLA
LDDIRESIEELKFYRTHFINLEK

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=175, Percent_Identity=52, Blast_Score=193, Evalue=7e-50,
Organism=Escherichia coli, GI87082382, Length=182, Percent_Identity=67.032967032967, Blast_Score=271, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17557752, Length=170, Percent_Identity=50, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=182, Percent_Identity=37.3626373626374, Blast_Score=121, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=45.4545454545455, Blast_Score=176, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_ACTP2 (A3N1D8)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053829.1
- ProteinModelPortal:   A3N1D8
- SMR:   A3N1D8
- STRING:   A3N1D8
- GeneID:   4850534
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1134
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   A3N1D8
- ProtClustDB:   PRK05359
- BioCyc:   APLE416269:APL_1134-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21572; Mature: 21441

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 130-130

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLDNQNLIWIDLEMTGLDPEKERIIEVATIVTDKDLNILAEGPVLTVHQSNDLLNKMS
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHEECCCCCEEECCCEEEEECCHHHHHHHH
DWCIKTHTENGLIERVKQSKLTERAVELQTIDFLKQWVPKGASPICGNSVAQDKRFLYKY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
MPDLADYFHYRHLDVSTLKELARRWKPDMLNAFNKKNTHLALDDIRESIEELKFYRTHFI
HHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHC
NLEK
CCCC
>Mature Secondary Structure 
SKLDNQNLIWIDLEMTGLDPEKERIIEVATIVTDKDLNILAEGPVLTVHQSNDLLNKMS
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHEECCCCCEEECCCEEEEECCHHHHHHHH
DWCIKTHTENGLIERVKQSKLTERAVELQTIDFLKQWVPKGASPICGNSVAQDKRFLYKY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
MPDLADYFHYRHLDVSTLKELARRWKPDMLNAFNKKNTHLALDDIRESIEELKFYRTHFI
HHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHC
NLEK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA