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The map label for this gene is queC

Identifier: 126208569

GI number: 126208569

Start: 1268863

End: 1269531

Strand: Direct

Name: queC

Synonym: APL_1097

Alternate gene names: 126208569

Gene position: 1268863-1269531 (Clockwise)

Preceding gene: 126208568

Following gene: 126208570

Centisome position: 55.79

GC content: 43.8

Gene sequence:

>669_bases
ATGAATTCAACCCCAAAAGCCGTCGTGATCTTTTCCGGCGGACAAGACTCTACGACTTGTCTTTTCCAGGCCATTCAAGA
ATTTGGTGTGGAAAATGTCGAAGTGGTAACCTTTCAATATGGTCAGCGTCATGCGATTGAGCTGGAAAAAGCGGCATGGA
TAGCGAAAGATCTCGGTGTGAAACAAACGCTGATTGACACTTCCGTGATCAAAGCCATCACATCTAATGCGATGATGGAA
GAACACGAAATTAAACAAGAAGGCAATACGCCGAATACCTTTGTTGATGGTCGTAATGCACTGTTTTTACTTTACACCGC
TATTTACGCCAAAGGACAAGGCATCCGAACCATTTTTACCGGTGTATGCGAAACCGACTTTAGCGGTTATCCGGACTGCC
GAGATGTGTTTGTGAAGTCGATGAATGTAACCCTCAATCTTGCGATGGACTATAATTTCAATATTCGCACACCGCTGATG
TACCTGACTAAAAAGCAAACTTGGGCATTAGCCGATAAGCTTGGTGCGTTCGATTATATCAGACAACACACCCACACCTG
CTATTTAGGCGTAGAAGGCGGTTGTCACACTTGCCCAAGCTGCGTGTTACGTGAAAAAGGGCTTAACGAATATCTATCAG
AAAAAACAAGCGGTCAAAAAAATGTTTAA

Upstream 100 bases:

>100_bases
TTTTTGCAAAAAAATTGCAAATTCAGACCGCTTATTCTTTCGTGGTTCGCAAACCTCCCACGCCAAAGATTCTCTTTGAA
ATCAAAACTAAGGATACAAA

Downstream 100 bases:

>100_bases
AATTGCAAAAGAATTTAGTTTCGATATGGCACATATGCTCGACGGGCACGACGGCAAATGCCAAAACTTACACGGACACA
CTTATAAACTTCAGGTGGAA

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNSTPKAVVIFSGGQDSTTCLFQAIQEFGVENVEVVTFQYGQRHAIELEKAAWIAKDLGVKQTLIDTSVIKAITSNAMME
EHEIKQEGNTPNTFVDGRNALFLLYTAIYAKGQGIRTIFTGVCETDFSGYPDCRDVFVKSMNVTLNLAMDYNFNIRTPLM
YLTKKQTWALADKLGAFDYIRQHTHTCYLGVEGGCHTCPSCVLREKGLNEYLSEKTSGQKNV

Sequences:

>Translated_222_residues
MNSTPKAVVIFSGGQDSTTCLFQAIQEFGVENVEVVTFQYGQRHAIELEKAAWIAKDLGVKQTLIDTSVIKAITSNAMME
EHEIKQEGNTPNTFVDGRNALFLLYTAIYAKGQGIRTIFTGVCETDFSGYPDCRDVFVKSMNVTLNLAMDYNFNIRTPLM
YLTKKQTWALADKLGAFDYIRQHTHTCYLGVEGGCHTCPSCVLREKGLNEYLSEKTSGQKNV
>Mature_222_residues
MNSTPKAVVIFSGGQDSTTCLFQAIQEFGVENVEVVTFQYGQRHAIELEKAAWIAKDLGVKQTLIDTSVIKAITSNAMME
EHEIKQEGNTPNTFVDGRNALFLLYTAIYAKGQGIRTIFTGVCETDFSGYPDCRDVFVKSMNVTLNLAMDYNFNIRTPLM
YLTKKQTWALADKLGAFDYIRQHTHTCYLGVEGGCHTCPSCVLREKGLNEYLSEKTSGQKNV

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=220, Percent_Identity=47.7272727272727, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_ACTP2 (A3N1A3)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053794.1
- ProteinModelPortal:   A3N1A3
- SMR:   A3N1A3
- STRING:   A3N1A3
- GeneID:   4849631
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1097
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   A3N1A3
- ProtClustDB:   CLSK870005
- BioCyc:   APLE416269:APL_1097-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24795; Mature: 24795

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTPKAVVIFSGGQDSTTCLFQAIQEFGVENVEVVTFQYGQRHAIELEKAAWIAKDLGV
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCC
KQTLIDTSVIKAITSNAMMEEHEIKQEGNTPNTFVDGRNALFLLYTAIYAKGQGIRTIFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHH
GVCETDFSGYPDCRDVFVKSMNVTLNLAMDYNFNIRTPLMYLTKKQTWALADKLGAFDYI
HHHCCCCCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHH
RQHTHTCYLGVEGGCHTCPSCVLREKGLNEYLSEKTSGQKNV
HHCCCEEEEECCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNSTPKAVVIFSGGQDSTTCLFQAIQEFGVENVEVVTFQYGQRHAIELEKAAWIAKDLGV
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHCCC
KQTLIDTSVIKAITSNAMMEEHEIKQEGNTPNTFVDGRNALFLLYTAIYAKGQGIRTIFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHH
GVCETDFSGYPDCRDVFVKSMNVTLNLAMDYNFNIRTPLMYLTKKQTWALADKLGAFDYI
HHHCCCCCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHH
RQHTHTCYLGVEGGCHTCPSCVLREKGLNEYLSEKTSGQKNV
HHCCCEEEEECCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA