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The map label for this gene is yihQ [C]

Identifier: 126208495

GI number: 126208495

Start: 1186618

End: 1188096

Strand: Direct

Name: yihQ [C]

Synonym: APL_1021

Alternate gene names: 126208495

Gene position: 1186618-1188096 (Clockwise)

Preceding gene: 126208491

Following gene: 126208496

Centisome position: 52.17

GC content: 36.85

Gene sequence:

>1479_bases
TTGTTATCGGGTTATACTTCTATCGGTAATAAGCGATATGTGTTTAATTGGAACTACGATAAAGTTCCTGCTCCTAATGC
GATGTCAGCTCATTTTCATCAGGCTGGTATGCATTTAGCTGCCAATATTAAACCTTGTTTATTACAAGATCACCCTCGTT
ATGAAGAAGTAAAAAACTTAGGTCTATTTATCCAAGATTCTGAATTTAATCAACCGGAACGCTCGGTATTTTGGGATGAT
GAAGGTTCTCATTTAGATTTTTCCAATCCGAAAACTATCGAATGGTGGAAACAAAATGTAACTAAGCAACTTCTGGAATA
TGGTATTGATTCAACTTGGAACGATAATAATGAATATGAAGTTTGGGACGGTAATGCAAAATGTGTCGGTTTCGGTAAAG
AAATTCCGATAAAACTTATTCGTCCGTTACAACCATTATTAATGATGAAATCTTCCTATGAAGCACAACGTGAATTTGCT
CCTAATTTACGTCCTTATCTAATTTCTCGCTCAGGAAGTCCGGGTATGAATCGTTATGTACAAACTTGGTCGGGAGATAA
TAGAACCAGCTGGAATACCTTACGTTACAACATTCGTATGGGACTTGGTATGAGCTTATCCGGTTTATATAACTTAGGTC
ATGATGTCGGCGGCTTCTCTGGAAATAAGCCTGAACCGGAATTATTTGTTCGCTGGGTTCAAAATGGTGTCATGCACCCT
CGTTTTACCATTCATTCTTGGAATGATGACAAAACCGTTAACGAGCCTTGGATGTATCCTGAAGTGACTCATATCATTAG
AGATACGATTAAACTTCGTTATCGTTTAATGCCGTATCTCTATAATACTTTCTGGAAAGCTCATCATGCATTAGAGTCGA
TGTTACGTCCGACTTTCTTGGATCATGAACACGATATCAATACTTTTGAAGAAAACGACGATTATCTTTTAGGTAAAGAT
TTACTTGTTGCTTCTGTGGTAGAGCAAGATCAACGTAAACGTGAGGTTTATTTACCGAAAAATAATGCGGGCTGGTATGA
TTTTTATGATCACACCTATCACCTCGACGGACAAACGATTACGACGGATGCGCCGCTTGAGAAAATCCCACTCTTTGTAA
AAGCAGGTGCAATCATTCCGATGTCTGCAAGAGAAGCTTATGTAGATCCCCAAAAAGATACCTATAGAGAGCTTATGGTT
TTCCCATTTATAAAAGCGGGGGAAGCGATAAATACTATTTACGATGATGACGGAGAAAGCTTCCGATATCAAAATAATGA
GTATTTACAATTAATGGTAAAATTACGTTGTTCAGAAACAAATATCTATATTGATATTCATAAACAAGGTAATTGGATAC
CGGCTTATAAAGAATTGAGAATAACGCTACCTGATAATGAAACAAGACAACTGGTCATAAACGGTAATGTCTTCACAAAA
GGAGAGTTATTTTCATTAAATAATCCTAAAGAGAGTTAA

Upstream 100 bases:

>100_bases
GTCAGGATAGAAAAACCGGCGCCTATTTATTTGGTACCGACGACAGTAAAAATTCGTAGATCTATGTGCTGAATATGATA
TTCCATGTGATTCATTCCAA

Downstream 100 bases:

>100_bases
AAAATGACAAGCAATGCAGATTTACGTTCATATAAAAAAATTGGTTCGATTTTAAAACAAGAATTAATTGACGGTATTTA
CCAAGTTGGCGAACGACTGC

Product: alpha-glucosidase 2

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MLSGYTSIGNKRYVFNWNYDKVPAPNAMSAHFHQAGMHLAANIKPCLLQDHPRYEEVKNLGLFIQDSEFNQPERSVFWDD
EGSHLDFSNPKTIEWWKQNVTKQLLEYGIDSTWNDNNEYEVWDGNAKCVGFGKEIPIKLIRPLQPLLMMKSSYEAQREFA
PNLRPYLISRSGSPGMNRYVQTWSGDNRTSWNTLRYNIRMGLGMSLSGLYNLGHDVGGFSGNKPEPELFVRWVQNGVMHP
RFTIHSWNDDKTVNEPWMYPEVTHIIRDTIKLRYRLMPYLYNTFWKAHHALESMLRPTFLDHEHDINTFEENDDYLLGKD
LLVASVVEQDQRKREVYLPKNNAGWYDFYDHTYHLDGQTITTDAPLEKIPLFVKAGAIIPMSAREAYVDPQKDTYRELMV
FPFIKAGEAINTIYDDDGESFRYQNNEYLQLMVKLRCSETNIYIDIHKQGNWIPAYKELRITLPDNETRQLVINGNVFTK
GELFSLNNPKES

Sequences:

>Translated_492_residues
MLSGYTSIGNKRYVFNWNYDKVPAPNAMSAHFHQAGMHLAANIKPCLLQDHPRYEEVKNLGLFIQDSEFNQPERSVFWDD
EGSHLDFSNPKTIEWWKQNVTKQLLEYGIDSTWNDNNEYEVWDGNAKCVGFGKEIPIKLIRPLQPLLMMKSSYEAQREFA
PNLRPYLISRSGSPGMNRYVQTWSGDNRTSWNTLRYNIRMGLGMSLSGLYNLGHDVGGFSGNKPEPELFVRWVQNGVMHP
RFTIHSWNDDKTVNEPWMYPEVTHIIRDTIKLRYRLMPYLYNTFWKAHHALESMLRPTFLDHEHDINTFEENDDYLLGKD
LLVASVVEQDQRKREVYLPKNNAGWYDFYDHTYHLDGQTITTDAPLEKIPLFVKAGAIIPMSAREAYVDPQKDTYRELMV
FPFIKAGEAINTIYDDDGESFRYQNNEYLQLMVKLRCSETNIYIDIHKQGNWIPAYKELRITLPDNETRQLVINGNVFTK
GELFSLNNPKES
>Mature_492_residues
MLSGYTSIGNKRYVFNWNYDKVPAPNAMSAHFHQAGMHLAANIKPCLLQDHPRYEEVKNLGLFIQDSEFNQPERSVFWDD
EGSHLDFSNPKTIEWWKQNVTKQLLEYGIDSTWNDNNEYEVWDGNAKCVGFGKEIPIKLIRPLQPLLMMKSSYEAQREFA
PNLRPYLISRSGSPGMNRYVQTWSGDNRTSWNTLRYNIRMGLGMSLSGLYNLGHDVGGFSGNKPEPELFVRWVQNGVMHP
RFTIHSWNDDKTVNEPWMYPEVTHIIRDTIKLRYRLMPYLYNTFWKAHHALESMLRPTFLDHEHDINTFEENDDYLLGKD
LLVASVVEQDQRKREVYLPKNNAGWYDFYDHTYHLDGQTITTDAPLEKIPLFVKAGAIIPMSAREAYVDPQKDTYRELMV
FPFIKAGEAINTIYDDDGESFRYQNNEYLQLMVKLRCSETNIYIDIHKQGNWIPAYKELRITLPDNETRQLVINGNVFTK
GELFSLNNPKES

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=424, Percent_Identity=30.8962264150943, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI88900491, Length=437, Percent_Identity=31.350114416476, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI38202257, Length=437, Percent_Identity=31.350114416476, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI119393895, Length=479, Percent_Identity=28.1837160751566, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI119393893, Length=479, Percent_Identity=28.1837160751566, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI119393891, Length=479, Percent_Identity=28.1837160751566, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI157364974, Length=412, Percent_Identity=26.2135922330097, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI221316699, Length=471, Percent_Identity=22.7176220806794, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI310115361, Length=232, Percent_Identity=32.3275862068966, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI2367323, Length=384, Percent_Identity=26.8229166666667, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI2367256, Length=420, Percent_Identity=23.3333333333333, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71991189, Length=434, Percent_Identity=29.7235023041475, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17560800, Length=455, Percent_Identity=28.7912087912088, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17560798, Length=455, Percent_Identity=28.7912087912088, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32563849, Length=272, Percent_Identity=30.1470588235294, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71985706, Length=272, Percent_Identity=26.4705882352941, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319706, Length=449, Percent_Identity=29.3986636971047, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24643749, Length=450, Percent_Identity=28.2222222222222, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24643753, Length=450, Percent_Identity=28.2222222222222, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24643751, Length=450, Percent_Identity=28.2222222222222, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24643746, Length=450, Percent_Identity=28.2222222222222, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21357605, Length=450, Percent_Identity=28.2222222222222, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24650054, Length=368, Percent_Identity=24.1847826086957, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 57514; Mature: 57514

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGYTSIGNKRYVFNWNYDKVPAPNAMSAHFHQAGMHLAANIKPCLLQDHPRYEEVKNL
CCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCEEECCCCCEEECCCCCHHHHHHC
GLFIQDSEFNQPERSVFWDDEGSHLDFSNPKTIEWWKQNVTKQLLEYGIDSTWNDNNEYE
CEEEECCCCCCCCCCEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
VWDGNAKCVGFGKEIPIKLIRPLQPLLMMKSSYEAQREFAPNLRPYLISRSGSPGMNRYV
EECCCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCCCCCHHE
QTWSGDNRTSWNTLRYNIRMGLGMSLSGLYNLGHDVGGFSGNKPEPELFVRWVQNGVMHP
EECCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
RFTIHSWNDDKTVNEPWMYPEVTHIIRDTIKLRYRLMPYLYNTFWKAHHALESMLRPTFL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DHEHDINTFEENDDYLLGKDLLVASVVEQDQRKREVYLPKNNAGWYDFYDHTYHLDGQTI
CCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCEEEECCCEE
TTDAPLEKIPLFVKAGAIIPMSAREAYVDPQKDTYRELMVFPFIKAGEAINTIYDDDGES
ECCCCHHHCCEEEECCEEEEECCCHHCCCCCHHHHHHHHHHCCHHCCCCCHHEECCCCCC
FRYQNNEYLQLMVKLRCSETNIYIDIHKQGNWIPAYKELRITLPDNETRQLVINGNVFTK
EEECCCCEEEEEEEEEECCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECCEEEC
GELFSLNNPKES
CEEEECCCCCCC
>Mature Secondary Structure
MLSGYTSIGNKRYVFNWNYDKVPAPNAMSAHFHQAGMHLAANIKPCLLQDHPRYEEVKNL
CCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCEEECCCCCEEECCCCCHHHHHHC
GLFIQDSEFNQPERSVFWDDEGSHLDFSNPKTIEWWKQNVTKQLLEYGIDSTWNDNNEYE
CEEEECCCCCCCCCCEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
VWDGNAKCVGFGKEIPIKLIRPLQPLLMMKSSYEAQREFAPNLRPYLISRSGSPGMNRYV
EECCCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCCCCCHHE
QTWSGDNRTSWNTLRYNIRMGLGMSLSGLYNLGHDVGGFSGNKPEPELFVRWVQNGVMHP
EECCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
RFTIHSWNDDKTVNEPWMYPEVTHIIRDTIKLRYRLMPYLYNTFWKAHHALESMLRPTFL
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DHEHDINTFEENDDYLLGKDLLVASVVEQDQRKREVYLPKNNAGWYDFYDHTYHLDGQTI
CCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCEEEECCCEE
TTDAPLEKIPLFVKAGAIIPMSAREAYVDPQKDTYRELMVFPFIKAGEAINTIYDDDGES
ECCCCHHHCCEEEECCEEEEECCCHHCCCCCHHHHHHHHHHCCHHCCCCCHHEECCCCCC
FRYQNNEYLQLMVKLRCSETNIYIDIHKQGNWIPAYKELRITLPDNETRQLVINGNVFTK
EEECCCCEEEEEEEEEECCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECCEEEC
GELFSLNNPKES
CEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]