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The map label for this gene is ppiD [H]

Identifier: 126208477

GI number: 126208477

Start: 1165846

End: 1167723

Strand: Reverse

Name: ppiD [H]

Synonym: APL_1003

Alternate gene names: 126208477

Gene position: 1167723-1165846 (Counterclockwise)

Preceding gene: 126208481

Following gene: 126208476

Centisome position: 51.34

GC content: 41.8

Gene sequence:

>1878_bases
ATGATTGAGAATATGCATGAACGGACGAAAGGTCCCGTTTTTAAAATTATTTTTGCCTTGGTATCTTTATCTTTCGTAAT
TACCGGTATCGGTACGGGGTTAGTCGGCGGTGACACGGCGGCGGTAAAAGTCAATGGTACGGAAATTACTCAACAAGCGT
TTAATGCGGCTAAAAACCGTCAGCAAAGCGTGTTAAACGCACAGATGGGAGAACGTTTTTGGGATTTGCTTGATACGCCG
GAATATGCAAAACAGTTTAATCAGTCCGTGTTAAACGGCTTAGTTGATGAAGAGTTATTACGTCAATACGCTAAAGAACT
GAAATTAGGTATTAGTGCGGAACAAATTAAATCGGAAATTGTAAATAGCTCGATATTCCAGCAAGACGGTAAATTTAGCA
ACGATTTGTATCAACAAACCTTAAGAAGTAACGGATTAAGCGCGGACGGCTACGCGGCAATCGTTAATGAAGGTATGCTT
TTCTCTCAAATCCAAGAAGGGGTTATCGGCAGTGACTTTAACGTACCGGAACAAGAAGCGTTATTAGCAAAACTGTTACT
TCAAAAACGTCAAGTTCGTTTGGCGAATTATTCGATTGCTAAGGAAGCGACGAATCAAGCGGCTTCGGCGGAAGAATTAC
AAAAATATTATGATGCGCATAAATCCGAATTAATCGAACCGGAAAAATTAACGGTGGAATATGTAACATTAACACCGACG
GACGTAGCTAATAATGTGCAAGTTAATGACGAGCAAGTCAAAACTTATTATGAAAAAAATAAAGCGGATTACGCGACTAA
AGGCGAAACTCGTTTCGCCCATATTCAGTTAGCGAATGAAACTGATGCTAAGGCTGTTGCGGAACAAGTGAAAAACGGAG
CTGATTTTGCCGAATTGGCCAAAACTAAATCAACCGATAAATTATCCGCTGCGCAAGGCGGGGATTTAGGTTGGGCGAAA
GCAGGTACTTTCCCGAAAGCGTTTGAAGCTGCCGCTGCGTCATTACAAGACGGTCAAGTAAGTGCGGTAGTTAATGTAGA
TGGTGCTTATCACATCATCAAAGTGTTGGAACGTAAGGCTGAAACGGTTATTCCGCTTGAGCAAGTAAAAGATCAAATTA
CTAAAACGATTCGCCAAGAATTGCTTCTAACCGAATATTCCAATATTGCGCGCGAAATGGCGAATAGAGCATTTGAGAAT
AGCGGCAGTTTGGAATCGGTTGCACAAGCAGGCGGTGTAAAAGTGCAAAAATCCGCACAATTTACCCAACAAAACGTGCC
GGCGGAACTGAATAATGAAAAAGTATTAAAAGCATTATTTAACGGAGAGTTACGCCAAAGCGGTCAGAATTCGGATGCGA
TGGATATCGGAGACGAACATAACCCGAAAACAATGTTTGTACGTGTAAGCGATTATCAAGCCGAACGTGTAAAAACCTTA
GAAGAAGCTAAAGCTGAGGTCACAGAGGCGATAAAACAGCAAAAAGCGGAACAAATCCTATTAGCGAAAGCGGAAGAACA
AGTTAAAGCGCTTAACGAAGGTAAAGATGAGAAAGTTTCTTTCGGTAATGCTCAGACGTTAGTATTCGCACAGGCGGAAA
GTGAGAATCCGTTATTAGCTCAAACGGTTTTTTCTATGCCGAAGCCGGCGGACAAAGCTGTTTATCAGGTAGCGCGTAAC
CAACAAGGCGATGTGATTATTGTTGCTTTAGATAAAGTGATCGACGGAAGCTTAGAGGAATTTAAACCGCTTTCGGTACA
ATTTGCTCAGGCGGAACAGACACTGTTACGTAATGATTTACTCAAAGACTTACGTGCCAGAGCTTCGATTGAAGTGAATC
AAGATTTTATGGGACAAGCGGAATCTCAAGCCCATTAA

Upstream 100 bases:

>100_bases
GTTGCCGGATAACGTTTTCTGAAAATTACACATTTGAGAATTACTTGGTTTACAGTATAATCACGACAATTTTTTGTAAT
GAACTTCTAGGAATTTATCC

Downstream 100 bases:

>100_bases
TTCGGTTTTGATTGATATTTAAAAACGCCTAAAACTGATATGTTCTAGGCGTTTTTGTTTTGTCTTATTTTTCTTACTCT
ATATAATAACGCATAATTCC

Product: peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MIENMHERTKGPVFKIIFALVSLSFVITGIGTGLVGGDTAAVKVNGTEITQQAFNAAKNRQQSVLNAQMGERFWDLLDTP
EYAKQFNQSVLNGLVDEELLRQYAKELKLGISAEQIKSEIVNSSIFQQDGKFSNDLYQQTLRSNGLSADGYAAIVNEGML
FSQIQEGVIGSDFNVPEQEALLAKLLLQKRQVRLANYSIAKEATNQAASAEELQKYYDAHKSELIEPEKLTVEYVTLTPT
DVANNVQVNDEQVKTYYEKNKADYATKGETRFAHIQLANETDAKAVAEQVKNGADFAELAKTKSTDKLSAAQGGDLGWAK
AGTFPKAFEAAAASLQDGQVSAVVNVDGAYHIIKVLERKAETVIPLEQVKDQITKTIRQELLLTEYSNIAREMANRAFEN
SGSLESVAQAGGVKVQKSAQFTQQNVPAELNNEKVLKALFNGELRQSGQNSDAMDIGDEHNPKTMFVRVSDYQAERVKTL
EEAKAEVTEAIKQQKAEQILLAKAEEQVKALNEGKDEKVSFGNAQTLVFAQAESENPLLAQTVFSMPKPADKAVYQVARN
QQGDVIIVALDKVIDGSLEEFKPLSVQFAQAEQTLLRNDLLKDLRARASIEVNQDFMGQAESQAH

Sequences:

>Translated_625_residues
MIENMHERTKGPVFKIIFALVSLSFVITGIGTGLVGGDTAAVKVNGTEITQQAFNAAKNRQQSVLNAQMGERFWDLLDTP
EYAKQFNQSVLNGLVDEELLRQYAKELKLGISAEQIKSEIVNSSIFQQDGKFSNDLYQQTLRSNGLSADGYAAIVNEGML
FSQIQEGVIGSDFNVPEQEALLAKLLLQKRQVRLANYSIAKEATNQAASAEELQKYYDAHKSELIEPEKLTVEYVTLTPT
DVANNVQVNDEQVKTYYEKNKADYATKGETRFAHIQLANETDAKAVAEQVKNGADFAELAKTKSTDKLSAAQGGDLGWAK
AGTFPKAFEAAAASLQDGQVSAVVNVDGAYHIIKVLERKAETVIPLEQVKDQITKTIRQELLLTEYSNIAREMANRAFEN
SGSLESVAQAGGVKVQKSAQFTQQNVPAELNNEKVLKALFNGELRQSGQNSDAMDIGDEHNPKTMFVRVSDYQAERVKTL
EEAKAEVTEAIKQQKAEQILLAKAEEQVKALNEGKDEKVSFGNAQTLVFAQAESENPLLAQTVFSMPKPADKAVYQVARN
QQGDVIIVALDKVIDGSLEEFKPLSVQFAQAEQTLLRNDLLKDLRARASIEVNQDFMGQAESQAH
>Mature_625_residues
MIENMHERTKGPVFKIIFALVSLSFVITGIGTGLVGGDTAAVKVNGTEITQQAFNAAKNRQQSVLNAQMGERFWDLLDTP
EYAKQFNQSVLNGLVDEELLRQYAKELKLGISAEQIKSEIVNSSIFQQDGKFSNDLYQQTLRSNGLSADGYAAIVNEGML
FSQIQEGVIGSDFNVPEQEALLAKLLLQKRQVRLANYSIAKEATNQAASAEELQKYYDAHKSELIEPEKLTVEYVTLTPT
DVANNVQVNDEQVKTYYEKNKADYATKGETRFAHIQLANETDAKAVAEQVKNGADFAELAKTKSTDKLSAAQGGDLGWAK
AGTFPKAFEAAAASLQDGQVSAVVNVDGAYHIIKVLERKAETVIPLEQVKDQITKTIRQELLLTEYSNIAREMANRAFEN
SGSLESVAQAGGVKVQKSAQFTQQNVPAELNNEKVLKALFNGELRQSGQNSDAMDIGDEHNPKTMFVRVSDYQAERVKTL
EEAKAEVTEAIKQQKAEQILLAKAEEQVKALNEGKDEKVSFGNAQTLVFAQAESENPLLAQTVFSMPKPADKAVYQVARN
QQGDVIIVALDKVIDGSLEEFKPLSVQFAQAEQTLLRNDLLKDLRARASIEVNQDFMGQAESQAH

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=628, Percent_Identity=33.9171974522293, Blast_Score=325, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68768; Mature: 68768

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENMHERTKGPVFKIIFALVSLSFVITGIGTGLVGGDTAAVKVNGTEITQQAFNAAKNR
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
QQSVLNAQMGERFWDLLDTPEYAKQFNQSVLNGLVDEELLRQYAKELKLGISAEQIKSEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VNSSIFQQDGKFSNDLYQQTLRSNGLSADGYAAIVNEGMLFSQIQEGVIGSDFNVPEQEA
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
LLAKLLLQKRQVRLANYSIAKEATNQAASAEELQKYYDAHKSELIEPEKLTVEYVTLTPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
DVANNVQVNDEQVKTYYEKNKADYATKGETRFAHIQLANETDAKAVAEQVKNGADFAELA
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHH
KTKSTDKLSAAQGGDLGWAKAGTFPKAFEAAAASLQDGQVSAVVNVDGAYHIIKVLERKA
HCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHH
ETVIPLEQVKDQITKTIRQELLLTEYSNIAREMANRAFENSGSLESVAQAGGVKVQKSAQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEHHHH
FTQQNVPAELNNEKVLKALFNGELRQSGQNSDAMDIGDEHNPKTMFVRVSDYQAERVKTL
HHHHCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
EEAKAEVTEAIKQQKAEQILLAKAEEQVKALNEGKDEKVSFGNAQTLVFAQAESENPLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCCHHH
QTVFSMPKPADKAVYQVARNQQGDVIIVALDKVIDGSLEEFKPLSVQFAQAEQTLLRNDL
HHHHCCCCCHHHHHHHHHCCCCCCEEEEEECHHHCCCHHHCCCCHHHHHHHHHHHHHHHH
LKDLRARASIEVNQDFMGQAESQAH
HHHHHHHCCCEECHHHHCCCCCCCC
>Mature Secondary Structure
MIENMHERTKGPVFKIIFALVSLSFVITGIGTGLVGGDTAAVKVNGTEITQQAFNAAKNR
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
QQSVLNAQMGERFWDLLDTPEYAKQFNQSVLNGLVDEELLRQYAKELKLGISAEQIKSEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VNSSIFQQDGKFSNDLYQQTLRSNGLSADGYAAIVNEGMLFSQIQEGVIGSDFNVPEQEA
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
LLAKLLLQKRQVRLANYSIAKEATNQAASAEELQKYYDAHKSELIEPEKLTVEYVTLTPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
DVANNVQVNDEQVKTYYEKNKADYATKGETRFAHIQLANETDAKAVAEQVKNGADFAELA
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHH
KTKSTDKLSAAQGGDLGWAKAGTFPKAFEAAAASLQDGQVSAVVNVDGAYHIIKVLERKA
HCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHH
ETVIPLEQVKDQITKTIRQELLLTEYSNIAREMANRAFENSGSLESVAQAGGVKVQKSAQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEHHHH
FTQQNVPAELNNEKVLKALFNGELRQSGQNSDAMDIGDEHNPKTMFVRVSDYQAERVKTL
HHHHCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
EEAKAEVTEAIKQQKAEQILLAKAEEQVKALNEGKDEKVSFGNAQTLVFAQAESENPLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCCHHH
QTVFSMPKPADKAVYQVARNQQGDVIIVALDKVIDGSLEEFKPLSVQFAQAEQTLLRNDL
HHHHCCCCCHHHHHHHHHCCCCCCEEEEEECHHHCCCHHHCCCCHHHHHHHHHHHHHHHH
LKDLRARASIEVNQDFMGQAESQAH
HHHHHHHCCCEECHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA