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The map label for this gene is bioD [H]

Identifier: 126208414

GI number: 126208414

Start: 1079580

End: 1080224

Strand: Reverse

Name: bioD [H]

Synonym: APL_0938

Alternate gene names: 126208414

Gene position: 1080224-1079580 (Counterclockwise)

Preceding gene: 126208415

Following gene: 126208413

Centisome position: 47.49

GC content: 40.16

Gene sequence:

>645_bases
ATGGGCAAAATCATTTTTGTATCAGGTATTGATACCGATATTGGTAAAACGATCGCCACCGGCTTTTATGCTAAACGCTT
GATGGAACAAGGCTATTCGGTAATCACTCAAAAGATGATTCAAACCGGCTGTGAGGGGATTTCCAGCGATATTTTGCAAC
ACCGTCAAATGCAGAATCTGCCACTCACGGAAGAAGATAAAGAGGGTATTACTTGTCCTTATCTTTTTCGCTATCCTTGT
TCGCCGCATTTGGCAGCGGAAATGGAAAATATCACGATTGATACGCATAAAATTGCCGAAGCCAGCCGATTATTAGCTGA
AAAATATGATTATGTTTTGTTAGAGGGAGCAGGCGGTTTAGCTGTGCCTTATGATAACCGACATACCACGCTTGATTATA
TTGCGGAGCAGCAATTACCGTTGATTTTAGTGACTTCCGGCAGATTAGGTTCGATTAATCATACCTTGCTCAGTTTAATG
GCGTGCCAACAAAAACAGATTCCGTTAGTCAGTTTGATCTATAATAGTTATCCACCAACAGACGAAATTATTCAGCAAAG
TACGCTAAACTATTTAAGAGAGTGTATTGAACGCAATTTCCCGGAAGCGGAATTTTTAGTAATGGACAAACAGCATGTTA
GATAA

Upstream 100 bases:

>100_bases
AGTTGATGGAATTTAGTGAACAATATCAAGCGCAATTTAGCTGTGAACAAGGCGTTTATTTGACTTATGCGCCTATTTTT
ATTTTGGGAGTGAAAAAATA

Downstream 100 bases:

>100_bases
CGAAGATTTTGCACTTTTCCAAGAAGCGGTAAAAGGCACGAAAAAAATTAAACAAGACACTTTTGTGCCGAAAACTGCGC
CTCGTAAAAAAGTTAATGAA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase 2; DTBS 2; Dethiobiotin synthase 2 [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MGKIIFVSGIDTDIGKTIATGFYAKRLMEQGYSVITQKMIQTGCEGISSDILQHRQMQNLPLTEEDKEGITCPYLFRYPC
SPHLAAEMENITIDTHKIAEASRLLAEKYDYVLLEGAGGLAVPYDNRHTTLDYIAEQQLPLILVTSGRLGSINHTLLSLM
ACQQKQIPLVSLIYNSYPPTDEIIQQSTLNYLRECIERNFPEAEFLVMDKQHVR

Sequences:

>Translated_214_residues
MGKIIFVSGIDTDIGKTIATGFYAKRLMEQGYSVITQKMIQTGCEGISSDILQHRQMQNLPLTEEDKEGITCPYLFRYPC
SPHLAAEMENITIDTHKIAEASRLLAEKYDYVLLEGAGGLAVPYDNRHTTLDYIAEQQLPLILVTSGRLGSINHTLLSLM
ACQQKQIPLVSLIYNSYPPTDEIIQQSTLNYLRECIERNFPEAEFLVMDKQHVR
>Mature_213_residues
GKIIFVSGIDTDIGKTIATGFYAKRLMEQGYSVITQKMIQTGCEGISSDILQHRQMQNLPLTEEDKEGITCPYLFRYPCS
PHLAAEMENITIDTHKIAEASRLLAEKYDYVLLEGAGGLAVPYDNRHTTLDYIAEQQLPLILVTSGRLGSINHTLLSLMA
CQQKQIPLVSLIYNSYPPTDEIIQQSTLNYLRECIERNFPEAEFLVMDKQHVR

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=184, Percent_Identity=32.0652173913043, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87081944, Length=195, Percent_Identity=27.1794871794872, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24187; Mature: 24056

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIIFVSGIDTDIGKTIATGFYAKRLMEQGYSVITQKMIQTGCEGISSDILQHRQMQNL
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PLTEEDKEGITCPYLFRYPCSPHLAAEMENITIDTHKIAEASRLLAEKYDYVLLEGAGGL
CCCCCCCCCCCCCEEEECCCCCHHHHHHHCCEECHHHHHHHHHHHHHHCCEEEEECCCCE
AVPYDNRHTTLDYIAEQQLPLILVTSGRLGSINHTLLSLMACQQKQIPLVSLIYNSYPPT
ECCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCH
DEIIQQSTLNYLRECIERNFPEAEFLVMDKQHVR
HHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCC
>Mature Secondary Structure 
GKIIFVSGIDTDIGKTIATGFYAKRLMEQGYSVITQKMIQTGCEGISSDILQHRQMQNL
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PLTEEDKEGITCPYLFRYPCSPHLAAEMENITIDTHKIAEASRLLAEKYDYVLLEGAGGL
CCCCCCCCCCCCCEEEECCCCCHHHHHHHCCEECHHHHHHHHHHHHHHCCEEEEECCCCE
AVPYDNRHTTLDYIAEQQLPLILVTSGRLGSINHTLLSLMACQQKQIPLVSLIYNSYPPT
ECCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCH
DEIIQQSTLNYLRECIERNFPEAEFLVMDKQHVR
HHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA