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The map label for this gene is bioC [H]

Identifier: 126208415

GI number: 126208415

Start: 1080224

End: 1080994

Strand: Reverse

Name: bioC [H]

Synonym: APL_0939

Alternate gene names: 126208415

Gene position: 1080994-1080224 (Counterclockwise)

Preceding gene: 126208416

Following gene: 126208414

Centisome position: 47.53

GC content: 41.89

Gene sequence:

>771_bases
ATGGCAGAGTTAGATAAGCCATTGATTGCACAACGTTTTGCAGCCCATATCACGGAATATGATGAGCATGCGATCGCTCA
ACAACAGATTAATCGACAATTGGTAAATTTGCTTGCCCAAACGAATAAACAATGTTTTCGGCGAGTGTTGGAAATCGGTT
GTGGTACGGGCGATTTAACTCAGCATTTAATGCGTGAATATCAAGTGGAACATTTGGCCGTCAATGATCTGAGTAATGTC
TATCAAGATTGCGTCGTGCAAAAAATTGGCGAAAATCGACCGCTTATTTCCTTTAAATTTATAGCCGGCGATGCGGAACA
TTTAGCCTTTGATGGACAATTTGATTTGATCAGTTCTGCGTCCGCAGTACAGTGGTTTGAACAGCCGCAAACTTTTGTTT
CGCAAGCCGCGAAGCTGTTACAGCCAAATGGTGTTTTGCTATTTAATAGTTTTACAACGGAAAATTTGGCGGAAATTCGT
GAACTAACGGGTGTCGGTCTGACTTACCCAAGCCCAGCAGATTGGCATTTTTGGTTAAGTAAAGACTTTACCCAGTTACA
GATTATGCAACGGCAGATTCGTTTAACCTTTGCTTCACCGCTTGCCGTGTTGCAACACCTGCGGAAAACCGGGGTAACGG
CAATTAGTACGCAAACCTGGACACGCAAAAAGTTGATGGAATTTAGTGAACAATATCAAGCGCAATTTAGCTGTGAACAA
GGCGTTTATTTGACTTATGCGCCTATTTTTATTTTGGGAGTGAAAAAATAA

Upstream 100 bases:

>100_bases
AAAATCAGCTAGCTTTTTGGCAAGATAAAAAGGTGCGTATGACACACCTATCTAAAGGTGAGCATTATCTCTGGCAACAT
TTTTCTGAGTGGGAACAATT

Downstream 100 bases:

>100_bases
TGGGCAAAATCATTTTTGTATCAGGTATTGATACCGATATTGGTAAAACGATCGCCACCGGCTTTTATGCTAAACGCTTG
ATGGAACAAGGCTATTCGGT

Product: biotin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MAELDKPLIAQRFAAHITEYDEHAIAQQQINRQLVNLLAQTNKQCFRRVLEIGCGTGDLTQHLMREYQVEHLAVNDLSNV
YQDCVVQKIGENRPLISFKFIAGDAEHLAFDGQFDLISSASAVQWFEQPQTFVSQAAKLLQPNGVLLFNSFTTENLAEIR
ELTGVGLTYPSPADWHFWLSKDFTQLQIMQRQIRLTFASPLAVLQHLRKTGVTAISTQTWTRKKLMEFSEQYQAQFSCEQ
GVYLTYAPIFILGVKK

Sequences:

>Translated_256_residues
MAELDKPLIAQRFAAHITEYDEHAIAQQQINRQLVNLLAQTNKQCFRRVLEIGCGTGDLTQHLMREYQVEHLAVNDLSNV
YQDCVVQKIGENRPLISFKFIAGDAEHLAFDGQFDLISSASAVQWFEQPQTFVSQAAKLLQPNGVLLFNSFTTENLAEIR
ELTGVGLTYPSPADWHFWLSKDFTQLQIMQRQIRLTFASPLAVLQHLRKTGVTAISTQTWTRKKLMEFSEQYQAQFSCEQ
GVYLTYAPIFILGVKK
>Mature_255_residues
AELDKPLIAQRFAAHITEYDEHAIAQQQINRQLVNLLAQTNKQCFRRVLEIGCGTGDLTQHLMREYQVEHLAVNDLSNVY
QDCVVQKIGENRPLISFKFIAGDAEHLAFDGQFDLISSASAVQWFEQPQTFVSQAAKLLQPNGVLLFNSFTTENLAEIRE
LTGVGLTYPSPADWHFWLSKDFTQLQIMQRQIRLTFASPLAVLQHLRKTGVTAISTQTWTRKKLMEFSEQYQAQFSCEQG
VYLTYAPIFILGVKK

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29202; Mature: 29071

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELDKPLIAQRFAAHITEYDEHAIAQQQINRQLVNLLAQTNKQCFRRVLEIGCGTGDLT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QHLMREYQVEHLAVNDLSNVYQDCVVQKIGENRPLISFKFIAGDAEHLAFDGQFDLISSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHEEECCCHHHHHHH
SAVQWFEQPQTFVSQAAKLLQPNGVLLFNSFTTENLAEIRELTGVGLTYPSPADWHFWLS
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
KDFTQLQIMQRQIRLTFASPLAVLQHLRKTGVTAISTQTWTRKKLMEFSEQYQAQFSCEQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCC
GVYLTYAPIFILGVKK
CEEEEEEEEEEEECCC
>Mature Secondary Structure 
AELDKPLIAQRFAAHITEYDEHAIAQQQINRQLVNLLAQTNKQCFRRVLEIGCGTGDLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QHLMREYQVEHLAVNDLSNVYQDCVVQKIGENRPLISFKFIAGDAEHLAFDGQFDLISSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHEEECCCHHHHHHH
SAVQWFEQPQTFVSQAAKLLQPNGVLLFNSFTTENLAEIRELTGVGLTYPSPADWHFWLS
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
KDFTQLQIMQRQIRLTFASPLAVLQHLRKTGVTAISTQTWTRKKLMEFSEQYQAQFSCEQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCC
GVYLTYAPIFILGVKK
CEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]