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The map label for this gene is ycjZ [C]

Identifier: 126208384

GI number: 126208384

Start: 1049704

End: 1050588

Strand: Direct

Name: ycjZ [C]

Synonym: APL_0908

Alternate gene names: 126208384

Gene position: 1049704-1050588 (Clockwise)

Preceding gene: 126208380

Following gene: 126208390

Centisome position: 46.15

GC content: 38.64

Gene sequence:

>885_bases
ATGCTTCAACGAGAAAACTATAATGATCTGTATGCATTTTTATGTGTTGCACGGGAACAGAATTTCACCAAAGCCGCCAC
TAAATTGGGTATTTCACAATCTGCGTTAAGTCGTACCATTAAACAGCTGGAATCTCGTTTAGGCGTACAACTCTTCGCTC
GAACCACTCGCCGATTATCACTAACTCACGCTGGTAACCAGCTTTTTCAAACCGCTGAACAAACATTTTCTAAACTCGAT
CACGAATTAGCGATGCTGGGACATTACCGTCAAACACCTTCTGGACAGGTAAGAATCACTGCTTCACAATATGCGATTGA
TAAAGTGTTATTACCTAAACTTGCTAAATTTCAAACACGATATCCTGAGATTCAACTCGAATTAATCAGCGATACTGCAT
TTTCCGACATTATTTCCGAGCAGTTTGATGCTGGTGTTCGCTTTGGAGATTTAGTTGCTGAAGGAATGATTGCGGTCAGA
ATTAGCAACGATGAAGAAATGGCGGTTATTGGATCACCTAATTATTTTCATACTCACGGATTTCCAAGAACACCTTCTGA
TTTAGCTCATCATCAATGCTTAAATTATCGTTATGCGAGTGGTGCGATGTATCACTGGGACTTCATCGTCAATCACGAGC
ACGTTCAAATTAAAACACAAGGACAGTGGACATTTTCTAATGATTATTCGATTCGAGATGCAGCAAAGTTAGGATTCGGA
CTAGGTTATATTTGTAAAGATTTGGTTCAAAAAGAATTGGAAAAAGGTGAGCTAATTCAAGTATTAAGTGAGTTTAGCTA
TACATTTGCTGGTTTTCATCTTTATTATCCGCACCGAAATATTTCGCCTGCATTGAAATGTGTGATTGATACGCTTAAGG
AATAA

Upstream 100 bases:

>100_bases
TGATAATGACCAAAAATTCAATAACATTTATTCACTCAGGTTCTAAATCAGGTAAAATAGCGGTTAAATTTCTCCTATTT
TTTACCACAAGATTTGAATT

Downstream 100 bases:

>100_bases
AATAAGCGGTAATTTTTTGCAAAAAACCTACAAAATTTTACCGCTTATCGTTTATTACCAGCCTTTTACAATACCGCCCG
GGAAGTGTTTAAGTGCTTCT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLQRENYNDLYAFLCVAREQNFTKAATKLGISQSALSRTIKQLESRLGVQLFARTTRRLSLTHAGNQLFQTAEQTFSKLD
HELAMLGHYRQTPSGQVRITASQYAIDKVLLPKLAKFQTRYPEIQLELISDTAFSDIISEQFDAGVRFGDLVAEGMIAVR
ISNDEEMAVIGSPNYFHTHGFPRTPSDLAHHQCLNYRYASGAMYHWDFIVNHEHVQIKTQGQWTFSNDYSIRDAAKLGFG
LGYICKDLVQKELEKGELIQVLSEFSYTFAGFHLYYPHRNISPALKCVIDTLKE

Sequences:

>Translated_294_residues
MLQRENYNDLYAFLCVAREQNFTKAATKLGISQSALSRTIKQLESRLGVQLFARTTRRLSLTHAGNQLFQTAEQTFSKLD
HELAMLGHYRQTPSGQVRITASQYAIDKVLLPKLAKFQTRYPEIQLELISDTAFSDIISEQFDAGVRFGDLVAEGMIAVR
ISNDEEMAVIGSPNYFHTHGFPRTPSDLAHHQCLNYRYASGAMYHWDFIVNHEHVQIKTQGQWTFSNDYSIRDAAKLGFG
LGYICKDLVQKELEKGELIQVLSEFSYTFAGFHLYYPHRNISPALKCVIDTLKE
>Mature_294_residues
MLQRENYNDLYAFLCVAREQNFTKAATKLGISQSALSRTIKQLESRLGVQLFARTTRRLSLTHAGNQLFQTAEQTFSKLD
HELAMLGHYRQTPSGQVRITASQYAIDKVLLPKLAKFQTRYPEIQLELISDTAFSDIISEQFDAGVRFGDLVAEGMIAVR
ISNDEEMAVIGSPNYFHTHGFPRTPSDLAHHQCLNYRYASGAMYHWDFIVNHEHVQIKTQGQWTFSNDYSIRDAAKLGFG
LGYICKDLVQKELEKGELIQVLSEFSYTFAGFHLYYPHRNISPALKCVIDTLKE

Specific function: May have a role in the regulation of oprD expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=294, Percent_Identity=39.4557823129252, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=37.1134020618557, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=28.8194444444444, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI145693193, Length=268, Percent_Identity=31.7164179104478, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87081978, Length=287, Percent_Identity=26.1324041811847, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=25.2559726962457, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788706, Length=269, Percent_Identity=28.2527881040892, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786448, Length=290, Percent_Identity=26.8965517241379, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789173, Length=271, Percent_Identity=29.1512915129151, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788748, Length=156, Percent_Identity=36.5384615384615, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789440, Length=268, Percent_Identity=21.6417910447761, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082132, Length=299, Percent_Identity=24.0802675585284, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI145693105, Length=147, Percent_Identity=29.9319727891156, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=183, Percent_Identity=31.1475409836066, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787879, Length=178, Percent_Identity=29.7752808988764, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367136, Length=302, Percent_Identity=23.1788079470199, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=287, Percent_Identity=25.4355400696864, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790011, Length=274, Percent_Identity=23.7226277372263, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786508, Length=184, Percent_Identity=27.7173913043478, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788296, Length=180, Percent_Identity=27.7777777777778, Blast_Score=61, Evalue=9e-11,
Organism=Escherichia coli, GI1790208, Length=168, Percent_Identity=29.1666666666667, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33543; Mature: 33543

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRENYNDLYAFLCVAREQNFTKAATKLGISQSALSRTIKQLESRLGVQLFARTTRRLS
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LTHAGNQLFQTAEQTFSKLDHELAMLGHYRQTPSGQVRITASQYAIDKVLLPKLAKFQTR
EHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCC
YPEIQLELISDTAFSDIISEQFDAGVRFGDLVAEGMIAVRISNDEEMAVIGSPNYFHTHG
CCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCEEEEECCCEEECCC
FPRTPSDLAHHQCLNYRYASGAMYHWDFIVNHEHVQIKTQGQWTFSNDYSIRDAAKLGFG
CCCCHHHHHHHHHHCEEECCCCEEEEEEEEECCEEEEEECCCEEECCCCCHHHHHHHCCC
LGYICKDLVQKELEKGELIQVLSEFSYTFAGFHLYYPHRNISPALKCVIDTLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLQRENYNDLYAFLCVAREQNFTKAATKLGISQSALSRTIKQLESRLGVQLFARTTRRLS
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LTHAGNQLFQTAEQTFSKLDHELAMLGHYRQTPSGQVRITASQYAIDKVLLPKLAKFQTR
EHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCC
YPEIQLELISDTAFSDIISEQFDAGVRFGDLVAEGMIAVRISNDEEMAVIGSPNYFHTHG
CCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCEEEEECCCEEECCC
FPRTPSDLAHHQCLNYRYASGAMYHWDFIVNHEHVQIKTQGQWTFSNDYSIRDAAKLGFG
CCCCHHHHHHHHHHCEEECCCCEEEEEEEEECCEEEEEECCCEEECCCCCHHHHHHHCCC
LGYICKDLVQKELEKGELIQVLSEFSYTFAGFHLYYPHRNISPALKCVIDTLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]