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The map label for this gene is sdaC [H]

Identifier: 126208332

GI number: 126208332

Start: 995022

End: 996251

Strand: Direct

Name: sdaC [H]

Synonym: APL_0856

Alternate gene names: 126208332

Gene position: 995022-996251 (Clockwise)

Preceding gene: 126208330

Following gene: 126208333

Centisome position: 43.75

GC content: 40.98

Gene sequence:

>1230_bases
ATGGCTACGCCATCTCATCGTTTTTCCCTCACTTGGGTGCTAAATCTGTTCGGTACTGCCGTTGGTGCAGGCGTATTATT
TTTACCGATTAACGCCGGTATGAGCGGTTTTTATCCGCTGATTGTCATGACCTTATTAGTCGGGCCGATGACTTATCTGG
CACACCGAGGGCTGGCTCGTTTTGTGCTGTCTTCCGGCAAACCGGGTAGTGATATTACCAACGTAGTACGTGAACATTTC
GGCGAAAACGCCGGTAAATTTATTACCTTACTCTACTTCTTTGCGATCTTCCCGATTCTATTAATTTATGGTGTCGGTAT
CACCAATACGGTCGGCTCATTTATTGAAAACCAATTACAGATGGCTGTACCGCCTCGCGCATTACTCTCGGGCGTATTAA
TTGCCGTTATGATTAGCGTAATGTTACTGAGTGAACAAGCGATGTTAAAAATCACCACTTACTTAGTTTATCCGTTAGTG
TTAATTCTGTTCGGTTTATCTATTTACCTAATTCCGGAATGGAATGGTGCCGCATTACAGCAAATGCCGAGTACAGGCGA
CTTCTTAACCACTTTATGGCTGACCATTCCCGTATTAGTGTTTGCCTTTAACCATTCGCCGGCAATTTCATCCTTTGCCC
TTTCACAACAAAAACATTATCAAGATCCGCAACAAACCGAAGTTGAATCAAGTAAAGTATTACGTTCAACCGCAATGATC
TTAGTGTTATTCGTGATGTTTTTCGTATTTAGCTGCGTACTTACGCTTACTCCGGAAGAGCTTGCACAAGCGAAAGCACA
AAATATTTCAATTTTGTCTTACTTAGCCAATAAATTTGATAATCCGGTTATTTCTTATTTCGGACCTTTCGTGGCATTCT
TAGCAATCGGTAGTTCTTTCTTCGGTCACTATTTAGGTGCGCGTGAAGGATTAGAAGGTTTAGTCAATCAATTACGTGAT
AAACCGATTGAATCGACAAAATTCAAAAAAATTACTGCGGTTGTTTTCTTTATCACATTATGGATTGTAGCAACCATTAA
CCCGAGTATTCTCGGTTTTATCGAAAGTTTAGGTGGTCCGATTATTGCGATGATTCTGTTTATTATGCCGGTTTATGCCA
TTTATACCGTGCCGGCATTAGCAAAATATAAAAGCAGTATCGCCAGCAATACTTTTGTTACCGTGATGGGAACCGTCGCT
ATTTCAGCGATTGTGTACGGATTATTATAA

Upstream 100 bases:

>100_bases
ATAAAATTGACATTTTTGACTTGTTTCATATAACCGAAAGATTATGATGCGTCCAAAATTTTATAAATTTATAACTCTAA
CATTTAAATAGGAGAATCTT

Downstream 100 bases:

>100_bases
TCGCTGTATAATCGCTCCCTTTCCAATTTTCAGGCAATAAACCTAATATATCTTTGGTGTTTATTGCCTTTTTAACATAG
AGTGTTTTAGATATTATGAT

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MATPSHRFSLTWVLNLFGTAVGAGVLFLPINAGMSGFYPLIVMTLLVGPMTYLAHRGLARFVLSSGKPGSDITNVVREHF
GENAGKFITLLYFFAIFPILLIYGVGITNTVGSFIENQLQMAVPPRALLSGVLIAVMISVMLLSEQAMLKITTYLVYPLV
LILFGLSIYLIPEWNGAALQQMPSTGDFLTTLWLTIPVLVFAFNHSPAISSFALSQQKHYQDPQQTEVESSKVLRSTAMI
LVLFVMFFVFSCVLTLTPEELAQAKAQNISILSYLANKFDNPVISYFGPFVAFLAIGSSFFGHYLGAREGLEGLVNQLRD
KPIESTKFKKITAVVFFITLWIVATINPSILGFIESLGGPIIAMILFIMPVYAIYTVPALAKYKSSIASNTFVTVMGTVA
ISAIVYGLL

Sequences:

>Translated_409_residues
MATPSHRFSLTWVLNLFGTAVGAGVLFLPINAGMSGFYPLIVMTLLVGPMTYLAHRGLARFVLSSGKPGSDITNVVREHF
GENAGKFITLLYFFAIFPILLIYGVGITNTVGSFIENQLQMAVPPRALLSGVLIAVMISVMLLSEQAMLKITTYLVYPLV
LILFGLSIYLIPEWNGAALQQMPSTGDFLTTLWLTIPVLVFAFNHSPAISSFALSQQKHYQDPQQTEVESSKVLRSTAMI
LVLFVMFFVFSCVLTLTPEELAQAKAQNISILSYLANKFDNPVISYFGPFVAFLAIGSSFFGHYLGAREGLEGLVNQLRD
KPIESTKFKKITAVVFFITLWIVATINPSILGFIESLGGPIIAMILFIMPVYAIYTVPALAKYKSSIASNTFVTVMGTVA
ISAIVYGLL
>Mature_408_residues
ATPSHRFSLTWVLNLFGTAVGAGVLFLPINAGMSGFYPLIVMTLLVGPMTYLAHRGLARFVLSSGKPGSDITNVVREHFG
ENAGKFITLLYFFAIFPILLIYGVGITNTVGSFIENQLQMAVPPRALLSGVLIAVMISVMLLSEQAMLKITTYLVYPLVL
ILFGLSIYLIPEWNGAALQQMPSTGDFLTTLWLTIPVLVFAFNHSPAISSFALSQQKHYQDPQQTEVESSKVLRSTAMIL
VLFVMFFVFSCVLTLTPEELAQAKAQNISILSYLANKFDNPVISYFGPFVAFLAIGSSFFGHYLGAREGLEGLVNQLRDK
PIESTKFKKITAVVFFITLWIVATINPSILGFIESLGGPIIAMILFIMPVYAIYTVPALAKYKSSIASNTFVTVMGTVAI
SAIVYGLL

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=406, Percent_Identity=59.6059113300493, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1789504, Length=426, Percent_Identity=42.9577464788732, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1789211, Length=401, Percent_Identity=34.4139650872818, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1789961, Length=390, Percent_Identity=26.4102564102564, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI145693183, Length=394, Percent_Identity=28.9340101522843, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 44707; Mature: 44575

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPSHRFSLTWVLNLFGTAVGAGVLFLPINAGMSGFYPLIVMTLLVGPMTYLAHRGLAR
CCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSSGKPGSDITNVVREHFGENAGKFITLLYFFAIFPILLIYGVGITNTVGSFIENQLQ
HHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MAVPPRALLSGVLIAVMISVMLLSEQAMLKITTYLVYPLVLILFGLSIYLIPEWNGAALQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
QMPSTGDFLTTLWLTIPVLVFAFNHSPAISSFALSQQKHYQDPQQTEVESSKVLRSTAMI
HCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LVLFVMFFVFSCVLTLTPEELAQAKAQNISILSYLANKFDNPVISYFGPFVAFLAIGSSF
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FGHYLGAREGLEGLVNQLRDKPIESTKFKKITAVVFFITLWIVATINPSILGFIESLGGP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCH
IIAMILFIMPVYAIYTVPALAKYKSSIASNTFVTVMGTVAISAIVYGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATPSHRFSLTWVLNLFGTAVGAGVLFLPINAGMSGFYPLIVMTLLVGPMTYLAHRGLAR
CCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSSGKPGSDITNVVREHFGENAGKFITLLYFFAIFPILLIYGVGITNTVGSFIENQLQ
HHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MAVPPRALLSGVLIAVMISVMLLSEQAMLKITTYLVYPLVLILFGLSIYLIPEWNGAALQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
QMPSTGDFLTTLWLTIPVLVFAFNHSPAISSFALSQQKHYQDPQQTEVESSKVLRSTAMI
HCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LVLFVMFFVFSCVLTLTPEELAQAKAQNISILSYLANKFDNPVISYFGPFVAFLAIGSSF
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FGHYLGAREGLEGLVNQLRDKPIESTKFKKITAVVFFITLWIVATINPSILGFIESLGGP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCH
IIAMILFIMPVYAIYTVPALAKYKSSIASNTFVTVMGTVAISAIVYGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]