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The map label for this gene is degS [H]

Identifier: 126208222

GI number: 126208222

Start: 847374

End: 848405

Strand: Reverse

Name: degS [H]

Synonym: APL_0742

Alternate gene names: 126208222

Gene position: 848405-847374 (Counterclockwise)

Preceding gene: 126208223

Following gene: 126208221

Centisome position: 37.3

GC content: 42.25

Gene sequence:

>1032_bases
ATGGTAAAGAAGATTGTACAAGCGATTGCACTAGGTTTATTTTGTGCGTTTCTCATCATTTTCGTTTCTCCGTTACTAAA
AGACAGATCGGTTACGGTAAATGGAAAAACCACGCATATCGAAAGTTATCATGATGCCGTTCAATTGGCGTCTCCCGCAG
TAGTAAACGTATATAACCATGCATTCAGTCAGGACGGAAAAACCTTTGAAGTGAAAAACTTGGGATCAGGAGTTATTATG
ACTTCCGACGGGTATATTCTCACGAATAAGCACGTGGTTCAGAATGCGGCTCAAATTATCGTTGCACTTCAAACAGGCAG
TATTTCAAATGCAAAACTAGTCGGTGACGATACGTTAACGGATCTGGCAGTATTAAAAATTGAAGCGGATAACCTTCCTA
CGATACCGCAAAATAATGAAAGACCGGTAAGAATCGGCGATGTAGTTTTAGCAATAGGTAACCCGTTTAATTTAGGGCAA
AGTATTACTCAAGGAATTATTAGCGCTACGGGGCGTAACGCATTAACGGACGGAGGTCGTCAAAACTTTATTCAAACCGA
TGCCTCTATCAATAGAGGCAATTCCGGCGGTGCTTTAGTCAATTCCGCCGGAGAACTTATCGGTATTAATACGCTCAGTT
TAGGCAAAACCAGCGATGAATTGGCGGAAGGGTTAAATTTTGCAATACCGATTAATTTAGCGACTCAAATTATGTCGAAG
ATTATTCAAGACGGACGCGTAATAAGAGGATATTTCGGCGTAAACAGTTCGCTATATTCGTCAATTTTTGACGAGGAAGA
TGCAAAGGGCGTATTAATTACCGGCGTCGCGATTAACGGTCCGGCGTATCAGGCGGGTATTGAAGAAAACGACAGAATTT
TAAAAGTCGGAGAAGTGGATGCGGTATCTCCGACACAGATGATGGATTTGCTCGGGAATATGAAGCCCGGAGCGAAAGTT
CAGGTAAAAGTGCTACGTGACGGAAAAGAATTTGATGCCGATGTGGTTATCGGCGAATTTCCGGAACTATAA

Upstream 100 bases:

>100_bases
AATTTTTAAAAATAGGAATAAGTTTAAGGTTTTAACCTTGTTCGTAGCGATGGTATTCTTATATAATATTTAAGCATAAG
AATATAAAAAGGAGATAAGT

Downstream 100 bases:

>100_bases
TGCTATTGGTTGATAAGTCAGGAAAAGATATGAATCATTTTATTATTACCGTTGATGGTCCAAGTGGCGCGGGCAAAGGT
ACTTTATGCCATGCATTGGC

Product: protease DegS precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MVKKIVQAIALGLFCAFLIIFVSPLLKDRSVTVNGKTTHIESYHDAVQLASPAVVNVYNHAFSQDGKTFEVKNLGSGVIM
TSDGYILTNKHVVQNAAQIIVALQTGSISNAKLVGDDTLTDLAVLKIEADNLPTIPQNNERPVRIGDVVLAIGNPFNLGQ
SITQGIISATGRNALTDGGRQNFIQTDASINRGNSGGALVNSAGELIGINTLSLGKTSDELAEGLNFAIPINLATQIMSK
IIQDGRVIRGYFGVNSSLYSSIFDEEDAKGVLITGVAINGPAYQAGIEENDRILKVGEVDAVSPTQMMDLLGNMKPGAKV
QVKVLRDGKEFDADVVIGEFPEL

Sequences:

>Translated_343_residues
MVKKIVQAIALGLFCAFLIIFVSPLLKDRSVTVNGKTTHIESYHDAVQLASPAVVNVYNHAFSQDGKTFEVKNLGSGVIM
TSDGYILTNKHVVQNAAQIIVALQTGSISNAKLVGDDTLTDLAVLKIEADNLPTIPQNNERPVRIGDVVLAIGNPFNLGQ
SITQGIISATGRNALTDGGRQNFIQTDASINRGNSGGALVNSAGELIGINTLSLGKTSDELAEGLNFAIPINLATQIMSK
IIQDGRVIRGYFGVNSSLYSSIFDEEDAKGVLITGVAINGPAYQAGIEENDRILKVGEVDAVSPTQMMDLLGNMKPGAKV
QVKVLRDGKEFDADVVIGEFPEL
>Mature_343_residues
MVKKIVQAIALGLFCAFLIIFVSPLLKDRSVTVNGKTTHIESYHDAVQLASPAVVNVYNHAFSQDGKTFEVKNLGSGVIM
TSDGYILTNKHVVQNAAQIIVALQTGSISNAKLVGDDTLTDLAVLKIEADNLPTIPQNNERPVRIGDVVLAIGNPFNLGQ
SITQGIISATGRNALTDGGRQNFIQTDASINRGNSGGALVNSAGELIGINTLSLGKTSDELAEGLNFAIPINLATQIMSK
IIQDGRVIRGYFGVNSSLYSSIFDEEDAKGVLITGVAINGPAYQAGIEENDRILKVGEVDAVSPTQMMDLLGNMKPGAKV
QVKVLRDGKEFDADVVIGEFPEL

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI7019477, Length=277, Percent_Identity=35.7400722021661, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4506141, Length=325, Percent_Identity=34.1538461538462, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI22129776, Length=279, Percent_Identity=35.4838709677419, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24308541, Length=198, Percent_Identity=36.8686868686869, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1789630, Length=352, Percent_Identity=50.2840909090909, Blast_Score=317, Evalue=6e-88,
Organism=Escherichia coli, GI1786356, Length=270, Percent_Identity=42.2222222222222, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1789629, Length=280, Percent_Identity=39.2857142857143, Blast_Score=177, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24646839, Length=264, Percent_Identity=30.6818181818182, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011783
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 36406; Mature: 36406

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKIVQAIALGLFCAFLIIFVSPLLKDRSVTVNGKTTHIESYHDAVQLASPAVVNVYNH
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHCCCHHEEHHHH
AFSQDGKTFEVKNLGSGVIMTSDGYILTNKHVVQNAAQIIVALQTGSISNAKLVGDDTLT
HHCCCCCEEEEEECCCCEEEECCCEEEECHHHHHHHEEEEEEEECCCCCCCEEECCCCCC
DLAVLKIEADNLPTIPQNNERPVRIGDVVLAIGNPFNLGQSITQGIISATGRNALTDGGR
CEEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
QNFIQTDASINRGNSGGALVNSAGELIGINTLSLGKTSDELAEGLNFAIPINLATQIMSK
CCEEECCCCCCCCCCCCEEEECCCCEEEEEEEECCCCHHHHHCCCCEEEEHHHHHHHHHH
IIQDGRVIRGYFGVNSSLYSSIFDEEDAKGVLITGVAINGPAYQAGIEENDRILKVGEVD
HHHCCCEEEEEECCCHHHHHHHCCCCCCCEEEEEEEEECCCCEECCCCCCCCEEEECCCC
AVSPTQMMDLLGNMKPGAKVQVKVLRDGKEFDADVVIGEFPEL
CCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCCCCC
>Mature Secondary Structure
MVKKIVQAIALGLFCAFLIIFVSPLLKDRSVTVNGKTTHIESYHDAVQLASPAVVNVYNH
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHCCCHHEEHHHH
AFSQDGKTFEVKNLGSGVIMTSDGYILTNKHVVQNAAQIIVALQTGSISNAKLVGDDTLT
HHCCCCCEEEEEECCCCEEEECCCEEEECHHHHHHHEEEEEEEECCCCCCCEEECCCCCC
DLAVLKIEADNLPTIPQNNERPVRIGDVVLAIGNPFNLGQSITQGIISATGRNALTDGGR
CEEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
QNFIQTDASINRGNSGGALVNSAGELIGINTLSLGKTSDELAEGLNFAIPINLATQIMSK
CCEEECCCCCCCCCCCCEEEECCCCEEEEEEEECCCCHHHHHCCCCEEEEHHHHHHHHHH
IIQDGRVIRGYFGVNSSLYSSIFDEEDAKGVLITGVAINGPAYQAGIEENDRILKVGEVD
HHHCCCEEEEEECCCHHHHHHHCCCCCCCEEEEEEEEECCCCEECCCCCCCCEEEECCCC
AVSPTQMMDLLGNMKPGAKVQVKVLRDGKEFDADVVIGEFPEL
CCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]