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The map label for this gene is cmkA [H]

Identifier: 126208221

GI number: 126208221

Start: 846670

End: 847344

Strand: Reverse

Name: cmkA [H]

Synonym: APL_0741

Alternate gene names: 126208221

Gene position: 847344-846670 (Counterclockwise)

Preceding gene: 126208222

Following gene: 126208220

Centisome position: 37.25

GC content: 42.52

Gene sequence:

>675_bases
ATGAATCATTTTATTATTACCGTTGATGGTCCAAGTGGCGCGGGCAAAGGTACTTTATGCCATGCATTGGCCGAAAAATT
AGGGTTCGACTTTTTAGATTCGGGAGCGATTTATCGCATTACGGCATTAGCTGCGGTTAAAGCGGGGATTGCATTGGATG
ATGAAGATGCTTTAGCGGAAATCGGTCGTCGTTTGGATGTAAAATTCGTGCCGAAAGACGGTGAAATTAATGTCATTCTA
AACGGTGAAAATGTCGGAGATCAAATTCGTACGGCGGAAGCGGGTCAAAATGCCTCTAAAGTTGCAGTATTTCCTAAGGT
TCGAGAGGCATTATTGCAACGCCAGCGAGATTTCAGTACGTCTAAAGGTTTAATTGCAGACGGTCGAGATATGGGAACAG
TGGTATTCCCTGAGGCGCAAGTAAAATTATTTTTGGACGCAAGTGCCGAAGAGCGCGCAAAAAGACGTGTAAAACAGTTG
CAAGAAAAGGGATTTAATGCTAACTTTGACGAGATTTTAGCCGAGATTAAAGAGCGTGATTTTCGAGATAGAAATCGTGA
GGTTGCGCCTTTGGTTCCGGCTAAAGACGCATTGCTACTTGATTCAACCAGCTTGTCTATCGATGAAGTGGTTCGACAGG
CTTTGGATCATATTAGTCAATATATTAAATTTTAA

Upstream 100 bases:

>100_bases
AGGTAAAAGTGCTACGTGACGGAAAAGAATTTGATGCCGATGTGGTTATCGGCGAATTTCCGGAACTATAATGCTATTGG
TTGATAAGTCAGGAAAAGAT

Downstream 100 bases:

>100_bases
TTTATTCGCCGAACATAGGATGTGTTCGGTCATTATTACTAACCCCGTTTAAACAGGATGTTAAATGGATGTTCATTTTT
ATTTAAGAAGAAAATTATGT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNHFIITVDGPSGAGKGTLCHALAEKLGFDFLDSGAIYRITALAAVKAGIALDDEDALAEIGRRLDVKFVPKDGEINVIL
NGENVGDQIRTAEAGQNASKVAVFPKVREALLQRQRDFSTSKGLIADGRDMGTVVFPEAQVKLFLDASAEERAKRRVKQL
QEKGFNANFDEILAEIKERDFRDRNREVAPLVPAKDALLLDSTSLSIDEVVRQALDHISQYIKF

Sequences:

>Translated_224_residues
MNHFIITVDGPSGAGKGTLCHALAEKLGFDFLDSGAIYRITALAAVKAGIALDDEDALAEIGRRLDVKFVPKDGEINVIL
NGENVGDQIRTAEAGQNASKVAVFPKVREALLQRQRDFSTSKGLIADGRDMGTVVFPEAQVKLFLDASAEERAKRRVKQL
QEKGFNANFDEILAEIKERDFRDRNREVAPLVPAKDALLLDSTSLSIDEVVRQALDHISQYIKF
>Mature_224_residues
MNHFIITVDGPSGAGKGTLCHALAEKLGFDFLDSGAIYRITALAAVKAGIALDDEDALAEIGRRLDVKFVPKDGEINVIL
NGENVGDQIRTAEAGQNASKVAVFPKVREALLQRQRDFSTSKGLIADGRDMGTVVFPEAQVKLFLDASAEERAKRRVKQL
QEKGFNANFDEILAEIKERDFRDRNREVAPLVPAKDALLLDSTSLSIDEVVRQALDHISQYIKF

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=220, Percent_Identity=62.7272727272727, Blast_Score=280, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 24608; Mature: 24608

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHFIITVDGPSGAGKGTLCHALAEKLGFDFLDSGAIYRITALAAVKAGIALDDEDALAE
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
IGRRLDVKFVPKDGEINVILNGENVGDQIRTAEAGQNASKVAVFPKVREALLQRQRDFST
HHHHCCEEECCCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCC
SKGLIADGRDMGTVVFPEAQVKLFLDASAEERAKRRVKQLQEKGFNANFDEILAEIKERD
CCCCEECCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FRDRNREVAPLVPAKDALLLDSTSLSIDEVVRQALDHISQYIKF
HHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHFIITVDGPSGAGKGTLCHALAEKLGFDFLDSGAIYRITALAAVKAGIALDDEDALAE
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
IGRRLDVKFVPKDGEINVILNGENVGDQIRTAEAGQNASKVAVFPKVREALLQRQRDFST
HHHHCCEEECCCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCC
SKGLIADGRDMGTVVFPEAQVKLFLDASAEERAKRRVKQLQEKGFNANFDEILAEIKERD
CCCCEECCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FRDRNREVAPLVPAKDALLLDSTSLSIDEVVRQALDHISQYIKF
HHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA