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The map label for this gene is nrdR

Identifier: 126208191

GI number: 126208191

Start: 821887

End: 822336

Strand: Reverse

Name: nrdR

Synonym: APL_0711

Alternate gene names: 126208191

Gene position: 822336-821887 (Counterclockwise)

Preceding gene: 126208192

Following gene: 126208188

Centisome position: 36.15

GC content: 42.67

Gene sequence:

>450_bases
ATGCGTTGTCCGTTTTGTGCCGCAGAGGAAACCAAAGTCGTCGATTCCCGCCTTGCCGCAGACGGTTATCAGATTCGCCG
TCGTCGTGAATGTACGAGCTGTAAAGAACGTTTTACGACATTTGAATCGGCGGAATTAGTTGTGCCTTATGTGATTAAAA
ATAACGGCAATCGAGTGCCTTTTGATGCGAATAAATTAAGAGTCAGCTTAAGTCGGGCTTTAGAAAAACGTCCGGTCAGT
GCGGATGACTTAGAAAAAGCAATCAGTAAGATTATTATTCAATTGCAGTCCACCGGCGAGCGAGAAGTGCCGAGTAAATT
AGTCGGTAGCCTTGCTATGGATGCGCTAAAGCAATTGGATAAGGTTGCCTATATTCGATTTGCTTCGGTATATCTTAGCT
TTGATGATATTGAAGAGTTTACCAAAGAAATTGAGAAGTTAAGAGAATAG

Upstream 100 bases:

>100_bases
TTTTGCAAGCGATCCAAACACAAGGCTTTTTCCTACAGATGCCGCCTCCGCCGGAAAATCTGTTAAAGACCTTTCTCGAG
CAAAATAGAGGAGAAGCATA

Downstream 100 bases:

>100_bases
AGAATATTAAGAGCATACGACGGTATTTTAGTCGTCTCTTTTAGCGCTTCTATCGAAATGCAAGCGGTTGATTTTTGTTA
AATTTTTACAAAAATCAACC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRCPFCAAEETKVVDSRLAADGYQIRRRRECTSCKERFTTFESAELVVPYVIKNNGNRVPFDANKLRVSLSRALEKRPVS
ADDLEKAISKIIIQLQSTGEREVPSKLVGSLAMDALKQLDKVAYIRFASVYLSFDDIEEFTKEIEKLRE

Sequences:

>Translated_149_residues
MRCPFCAAEETKVVDSRLAADGYQIRRRRECTSCKERFTTFESAELVVPYVIKNNGNRVPFDANKLRVSLSRALEKRPVS
ADDLEKAISKIIIQLQSTGEREVPSKLVGSLAMDALKQLDKVAYIRFASVYLSFDDIEEFTKEIEKLRE
>Mature_149_residues
MRCPFCAAEETKVVDSRLAADGYQIRRRRECTSCKERFTTFESAELVVPYVIKNNGNRVPFDANKLRVSLSRALEKRPVS
ADDLEKAISKIIIQLQSTGEREVPSKLVGSLAMDALKQLDKVAYIRFASVYLSFDDIEEFTKEIEKLRE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=63.9455782312925, Blast_Score=197, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ACTP2 (A3N075)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053416.1
- STRING:   A3N075
- GeneID:   4849670
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0711
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   A3N075
- ProtClustDB:   PRK00464
- BioCyc:   APLE416269:APL_0711-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17011; Mature: 17011

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCAAEETKVVDSRLAADGYQIRRRRECTSCKERFTTFESAELVVPYVIKNNGNRVP
CCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCC
FDANKLRVSLSRALEKRPVSADDLEKAISKIIIQLQSTGEREVPSKLVGSLAMDALKQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KVAYIRFASVYLSFDDIEEFTKEIEKLRE
HHHHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRCPFCAAEETKVVDSRLAADGYQIRRRRECTSCKERFTTFESAELVVPYVIKNNGNRVP
CCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCC
FDANKLRVSLSRALEKRPVSADDLEKAISKIIIQLQSTGEREVPSKLVGSLAMDALKQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KVAYIRFASVYLSFDDIEEFTKEIEKLRE
HHHHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA