Click here to switch to the map view.

The map label for this gene is serC [H]

Identifier: 126208182

GI number: 126208182

Start: 805273

End: 806361

Strand: Reverse

Name: serC [H]

Synonym: APL_0702

Alternate gene names: 126208182

Gene position: 806361-805273 (Counterclockwise)

Preceding gene: 126208183

Following gene: 126208181

Centisome position: 35.45

GC content: 40.96

Gene sequence:

>1089_bases
ATGACACAAGTTTATAATTTTAGCGCAGGTCCGGCGATGATGCCGAAAGCCGTTTTGGAACAAGCTCAACAAGAATTATT
AAATTGGCAAAATCAAGGGACTTCGGTGATGGAAGTCAGCCATCGCGGTAAATTGTTTATGGAGTTAGCGACACAGTCGG
AGAAAGATCTGCGTGAAGTCTATAATATTCCGGATAACTATAAGATCCTATTTTTACAAGGCGGTGCGAGAGGACAATTT
GCGGCGATTCCAATGAATTTGATCGGCGAAAAGGGTAAGGCTCTTTATTTAAACAGCGGTCATTGGTCCGGAACGGCGGC
AAAAGAAGCACGTAATTTCTGCGAAATCGATGAAATCAATATTGTAGAAAAAGATCAAAACGGGATCATTTCCGTTACTC
GTACCGATTTCAGCGACATCGCCGATCAATACGATTATGTGCATTATTGCCCGAACGAAACGATTAGCGGGGTGGAAATT
CACGAGATTCCGAATGTAGGTAATGCCGTATTGGTTGCGGATATGTCTTCAAATATTCTTTCACGTAAAATCGATATTAA
TAAATTCGGTTTAATTTATGCCGGCGCACAAAAGAATTTAGGTCCGGCAGGTATTACGATAGTGATTGTACGTGAAGATC
TAATTGGTAAGGCGCGTACCGCTACACCGTCTATTTGGAATTACGAAACGCAAGTCAATGCCGATTCAATGATCAATACG
CCGCCGACATTCGCATGGTATTTATGTTCATTGGTATTTAAACATTTAATCAAAGAAGGCGGTTTACCGGCGATTGAAAA
ACGTAATGAAGCTAAAGCGAAATTGTTGTACGACTATTTAAATAACAGCAACTTCTATCGTAATTATATTGCCGAAGCCA
ATCGTTCCGTGATGAATGTAACCTTTACCACCGATAATGACGAATTAAATGCAAAATTTGTGGCGGAAGCGACCGCTTGC
GGTTTACATGCTTTAAAAGGACACAAAGTGTTAGGCGGTATGCGTGCATCAATCTATAACGCTATGCCGATTGAAGGCGT
GCAAGCGTTAATTGGATTTATGGATAAATTTGCGAAAGAAAACGCGTAA

Upstream 100 bases:

>100_bases
ATAGAAAAGTTTTTTCCGCAAAAAAGTGCTTTTAAAGTAGTGAATATTTTCGCTAGAATGGCTAAATCAGTTTTTAAAAA
CACACAAAGAGGCAAACACA

Downstream 100 bases:

>100_bases
TACTTGAGCGTATATAAAAAGAAACCATCTGCCGTGCAGGTGGTTTTTTTACAGGTCGATTTTATGTTTCCGATAAGTTT
TAATATATTATTTTATTTTG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTQVYNFSAGPAMMPKAVLEQAQQELLNWQNQGTSVMEVSHRGKLFMELATQSEKDLREVYNIPDNYKILFLQGGARGQF
AAIPMNLIGEKGKALYLNSGHWSGTAAKEARNFCEIDEINIVEKDQNGIISVTRTDFSDIADQYDYVHYCPNETISGVEI
HEIPNVGNAVLVADMSSNILSRKIDINKFGLIYAGAQKNLGPAGITIVIVREDLIGKARTATPSIWNYETQVNADSMINT
PPTFAWYLCSLVFKHLIKEGGLPAIEKRNEAKAKLLYDYLNNSNFYRNYIAEANRSVMNVTFTTDNDELNAKFVAEATAC
GLHALKGHKVLGGMRASIYNAMPIEGVQALIGFMDKFAKENA

Sequences:

>Translated_362_residues
MTQVYNFSAGPAMMPKAVLEQAQQELLNWQNQGTSVMEVSHRGKLFMELATQSEKDLREVYNIPDNYKILFLQGGARGQF
AAIPMNLIGEKGKALYLNSGHWSGTAAKEARNFCEIDEINIVEKDQNGIISVTRTDFSDIADQYDYVHYCPNETISGVEI
HEIPNVGNAVLVADMSSNILSRKIDINKFGLIYAGAQKNLGPAGITIVIVREDLIGKARTATPSIWNYETQVNADSMINT
PPTFAWYLCSLVFKHLIKEGGLPAIEKRNEAKAKLLYDYLNNSNFYRNYIAEANRSVMNVTFTTDNDELNAKFVAEATAC
GLHALKGHKVLGGMRASIYNAMPIEGVQALIGFMDKFAKENA
>Mature_361_residues
TQVYNFSAGPAMMPKAVLEQAQQELLNWQNQGTSVMEVSHRGKLFMELATQSEKDLREVYNIPDNYKILFLQGGARGQFA
AIPMNLIGEKGKALYLNSGHWSGTAAKEARNFCEIDEINIVEKDQNGIISVTRTDFSDIADQYDYVHYCPNETISGVEIH
EIPNVGNAVLVADMSSNILSRKIDINKFGLIYAGAQKNLGPAGITIVIVREDLIGKARTATPSIWNYETQVNADSMINTP
PTFAWYLCSLVFKHLIKEGGLPAIEKRNEAKAKLLYDYLNNSNFYRNYIAEANRSVMNVTFTTDNDELNAKFVAEATACG
LHALKGHKVLGGMRASIYNAMPIEGVQALIGFMDKFAKENA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=362, Percent_Identity=44.7513812154696, Blast_Score=312, Evalue=4e-85,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=40.8963585434174, Blast_Score=270, Evalue=2e-72,
Organism=Escherichia coli, GI1787136, Length=362, Percent_Identity=54.4198895027624, Blast_Score=418, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=43.9226519337017, Blast_Score=291, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6324758, Length=392, Percent_Identity=39.7959183673469, Blast_Score=269, Evalue=5e-73,
Organism=Drosophila melanogaster, GI21356589, Length=364, Percent_Identity=46.7032967032967, Blast_Score=317, Evalue=6e-87,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40166; Mature: 40035

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVYNFSAGPAMMPKAVLEQAQQELLNWQNQGTSVMEVSHRGKLFMELATQSEKDLREV
CCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHCCHHHHHHH
YNIPDNYKILFLQGGARGQFAAIPMNLIGEKGKALYLNSGHWSGTAAKEARNFCEIDEIN
HCCCCCCEEEEEECCCCCCEEEECHHHHCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEE
IVEKDQNGIISVTRTDFSDIADQYDYVHYCPNETISGVEIHEIPNVGNAVLVADMSSNIL
EEEECCCCEEEEEECCHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCHH
SRKIDINKFGLIYAGAQKNLGPAGITIVIVREDLIGKARTATPSIWNYETQVNADSMINT
HHCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCC
PPTFAWYLCSLVFKHLIKEGGLPAIEKRNEAKAKLLYDYLNNSNFYRNYIAEANRSVMNV
CCHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEE
TFTTDNDELNAKFVAEATACGLHALKGHKVLGGMRASIYNAMPIEGVQALIGFMDKFAKE
EEECCCCCCCEEEEEHHHHHHHHHHCCCHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHC
NA
CC
>Mature Secondary Structure 
TQVYNFSAGPAMMPKAVLEQAQQELLNWQNQGTSVMEVSHRGKLFMELATQSEKDLREV
CEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHCCHHHHHHH
YNIPDNYKILFLQGGARGQFAAIPMNLIGEKGKALYLNSGHWSGTAAKEARNFCEIDEIN
HCCCCCCEEEEEECCCCCCEEEECHHHHCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEE
IVEKDQNGIISVTRTDFSDIADQYDYVHYCPNETISGVEIHEIPNVGNAVLVADMSSNIL
EEEECCCCEEEEEECCHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCHH
SRKIDINKFGLIYAGAQKNLGPAGITIVIVREDLIGKARTATPSIWNYETQVNADSMINT
HHCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCC
PPTFAWYLCSLVFKHLIKEGGLPAIEKRNEAKAKLLYDYLNNSNFYRNYIAEANRSVMNV
CCHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEE
TFTTDNDELNAKFVAEATACGLHALKGHKVLGGMRASIYNAMPIEGVQALIGFMDKFAKE
EEECCCCCCCEEEEEHHHHHHHHHHCCCHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHC
NA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA