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The map label for this gene is moaC [H]

Identifier: 126208171

GI number: 126208171

Start: 792354

End: 792830

Strand: Direct

Name: moaC [H]

Synonym: APL_0691

Alternate gene names: 126208171

Gene position: 792354-792830 (Clockwise)

Preceding gene: 126208170

Following gene: 126208172

Centisome position: 34.84

GC content: 43.19

Gene sequence:

>477_bases
ATGAACCAATTTACTCACATCAATACCAACGGCGAAGCCAATATGGTCGATGTTTCGATGAAACAAGAAACTGTCCGTGT
GGCTCGTGCCGAAGCATTCGTTTCGATGAATGCCGAAACATTACAAATGATTATTTCCGGTAACCATCACAAAGGCGATG
TATTTGCGACTGCTCGTATAGCAGGTATTCAAGCGGCAAAAAGAACCTGGGAACTTATTCCACTTTGCCACCCACTACTC
CTCTCAAAAGTTGAAGTGCAACTTGAAGCGCTGCCGGAAACCAATCAAGTACGCATCGAATCACTGTGCAAATTAACCGG
TAAAACCGGTGTGGAAATGGAAGCGCTAACCGCTGCCAGTGTTGCTGCACTAACGATTTACGATATGTGTAAAGCGGTAC
AAAAAGATATGGTGATTGAAAATGTTCGTTTACTACATAAAAGTGGTGGTAAATCGGGCGAATTTAATGCGGAATAA

Upstream 100 bases:

>100_bases
GGTGAAGCAGGGTCGCCTTTCTTTGGTTATTTCTTTGGCGAAGCAAAGAAAGTGACAGAAAAAGCAATGATTCAATGTTA
TTAATATTAAAATACTTATC

Downstream 100 bases:

>100_bases
GAATTACATTTAGGGATAAATATGATTAACGTTTTATTTTTTGCACAGGTACGCGAATTGGTCGGCGTTGATGCTTTAAC
CGTTCCTGCCGAATTCGAAA

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MNQFTHINTNGEANMVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIPLCHPLL
LSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIENVRLLHKSGGKSGEFNAE

Sequences:

>Translated_158_residues
MNQFTHINTNGEANMVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIPLCHPLL
LSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIENVRLLHKSGGKSGEFNAE
>Mature_158_residues
MNQFTHINTNGEANMVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIPLCHPLL
LSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIENVRLLHKSGGKSGEFNAE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=81.6455696202532, Blast_Score=267, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.2953020134228, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=55.4140127388535, Blast_Score=163, Evalue=4e-41,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=56.9444444444444, Blast_Score=153, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17295; Mature: 17295

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFTHINTNGEANMVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARI
CCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLLLSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIENVRLLHKSGGKSGEFNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNQFTHINTNGEANMVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARI
CCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLLLSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIENVRLLHKSGGKSGEFNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA