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The map label for this gene is sbcB [H]

Identifier: 126208153

GI number: 126208153

Start: 767214

End: 768758

Strand: Reverse

Name: sbcB [H]

Synonym: APL_0673

Alternate gene names: 126208153

Gene position: 768758-767214 (Counterclockwise)

Preceding gene: 126208154

Following gene: 126208152

Centisome position: 33.8

GC content: 42.91

Gene sequence:

>1545_bases
ATGAATAAAAATCTTACTTTTTTCTTTTATGATTACGAAAGTTTCGGTGTGAGTCCGGCGTTAGATCGTCCGGCACAGTT
TGCCTGTATTCGTACCGATAGTGATTTTAATATCATCGGTGAGCCGGTGATGTTTTATTGTAAGCAAACACCGGATTATT
TACCTTCGCCTGAAGCGGTGATGGTGACGGGTATTACTCCGCAACAGTGTAACGCTGAAGGCGTGCCGGAACCGGAATTT
GCTGCACGAATCCACGCTGAATTCAGCCAGCCGAACACTTGCATTTTAGGCTATAACAATATTCGTTATGACGATGAAAT
GACCCGTTATACCTTTTTCCGCAATTTCTTTGACCCGTATGAATATAGCTGGAAAAATGGTAATTCTCGTTGGGATCTGT
TAGATCTTGTTCGAGCTTGTTATGCACTGCGTCCGGACGGCATTGAATGGGTAATAGATGAAAACGGTGTGCCGAATTTC
AAATTAGAGAATCTCACTAAAGCGAACGGCATTGCTCATGAAAATGCGCACGATGCAATGGCGGACGTTTACGCCACGAT
TGCGATGGCGAAATTGATTAAGCAAAAACAGCCGAAACTTTTCCAATTTTTCTTTGAAAATCGTGGTAAGAAAGAAATTG
AGAAAATGATTGATACCGGTGAAATGACCCCGTTGGTACACGTTTCCGGCATGTTCGGTAATGCGCGTGCTAATACCGCT
TGGATTGCACCGATTGCGTGGCACCCAACTAATCAAAATCAAGTGTTATGTTGCGATCTATCCGGCGATGTTAGTGCCTT
ATTAACGGATTCAGCGGAAGAATTACGTACTCGTCTATACACTAAAAAAGAAGAGCTGGCTGAAGCTGTTGCACCCGTTC
CATTAAAAGGGGTACATATTAATCGTTGTCCGATTATTGCCCCAGCAAAAGTGTTGTTGCCTGAAAATGCGGCTCGCTTA
GGCATTGATCGTGAGCGTTGTTTGGAAAATCTCAAATTACTGAAGGCGAATAAAAGTTTAGTGCGTGAGAAAGTGACCGA
AATTTTTATGGAAGAACGGAGCTTTGAACCTTCTGCGAATGTGGAAACCACGCTGTATGACGGCTTTTTCTCACCGGCAG
ATAAAAATAATATGGCGATTTTGCGTACGTTACCGCCACAAGAATTGGCGCATCACGGCTTACAGTTTGCCGATGAACGA
GTAGAAGCTTTGTTATTTCATTATCGAGCCAGACATTATCCCGAAACATTGAGCCGAGCGGAACAGATTAAATGGCAGAA
ATATTGTCATCAGCAGATAGATGCCAAATCGGCACAATTTGCCGAAGCGATTGATAGCTTATTCCAAATTCATCACGATA
ATCCGGAAAAGGTAAAATTATTGGAAAATTTGACCGCTTACGCTGCACAAATTGCGGAATTTCAGGTAGTTAAACACACC
GCTAATGCGCAAAGCGAGCAGCTAGTTTCAGCCTTAAACCAAGTGGCGGAACAGGGTATGGATAAAGCGGCGAAGTTGGA
AATGCTAAAGGCATTAATTAAATAA

Upstream 100 bases:

>100_bases
TTTTTTATGCCCGCAATTCTTTTAATTTGTAAAATTTCCTGCAAATTTAACCGCTTAGCTATGTTACAATGTGACTAATT
TTTCCTAATTGAAGCGATCA

Downstream 100 bases:

>100_bases
GTGGGAGAAAACGGCTATGCAACAACCTTTAGAACATCATCCGTTTCAACCTGTGCTACCGACCTCCGCAACCGTAGTGA
TGATGGGGACTTTTCCGCCG

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MNKNLTFFFYDYESFGVSPALDRPAQFACIRTDSDFNIIGEPVMFYCKQTPDYLPSPEAVMVTGITPQQCNAEGVPEPEF
AARIHAEFSQPNTCILGYNNIRYDDEMTRYTFFRNFFDPYEYSWKNGNSRWDLLDLVRACYALRPDGIEWVIDENGVPNF
KLENLTKANGIAHENAHDAMADVYATIAMAKLIKQKQPKLFQFFFENRGKKEIEKMIDTGEMTPLVHVSGMFGNARANTA
WIAPIAWHPTNQNQVLCCDLSGDVSALLTDSAEELRTRLYTKKEELAEAVAPVPLKGVHINRCPIIAPAKVLLPENAARL
GIDRERCLENLKLLKANKSLVREKVTEIFMEERSFEPSANVETTLYDGFFSPADKNNMAILRTLPPQELAHHGLQFADER
VEALLFHYRARHYPETLSRAEQIKWQKYCHQQIDAKSAQFAEAIDSLFQIHHDNPEKVKLLENLTAYAAQIAEFQVVKHT
ANAQSEQLVSALNQVAEQGMDKAAKLEMLKALIK

Sequences:

>Translated_514_residues
MNKNLTFFFYDYESFGVSPALDRPAQFACIRTDSDFNIIGEPVMFYCKQTPDYLPSPEAVMVTGITPQQCNAEGVPEPEF
AARIHAEFSQPNTCILGYNNIRYDDEMTRYTFFRNFFDPYEYSWKNGNSRWDLLDLVRACYALRPDGIEWVIDENGVPNF
KLENLTKANGIAHENAHDAMADVYATIAMAKLIKQKQPKLFQFFFENRGKKEIEKMIDTGEMTPLVHVSGMFGNARANTA
WIAPIAWHPTNQNQVLCCDLSGDVSALLTDSAEELRTRLYTKKEELAEAVAPVPLKGVHINRCPIIAPAKVLLPENAARL
GIDRERCLENLKLLKANKSLVREKVTEIFMEERSFEPSANVETTLYDGFFSPADKNNMAILRTLPPQELAHHGLQFADER
VEALLFHYRARHYPETLSRAEQIKWQKYCHQQIDAKSAQFAEAIDSLFQIHHDNPEKVKLLENLTAYAAQIAEFQVVKHT
ANAQSEQLVSALNQVAEQGMDKAAKLEMLKALIK
>Mature_514_residues
MNKNLTFFFYDYESFGVSPALDRPAQFACIRTDSDFNIIGEPVMFYCKQTPDYLPSPEAVMVTGITPQQCNAEGVPEPEF
AARIHAEFSQPNTCILGYNNIRYDDEMTRYTFFRNFFDPYEYSWKNGNSRWDLLDLVRACYALRPDGIEWVIDENGVPNF
KLENLTKANGIAHENAHDAMADVYATIAMAKLIKQKQPKLFQFFFENRGKKEIEKMIDTGEMTPLVHVSGMFGNARANTA
WIAPIAWHPTNQNQVLCCDLSGDVSALLTDSAEELRTRLYTKKEELAEAVAPVPLKGVHINRCPIIAPAKVLLPENAARL
GIDRERCLENLKLLKANKSLVREKVTEIFMEERSFEPSANVETTLYDGFFSPADKNNMAILRTLPPQELAHHGLQFADER
VEALLFHYRARHYPETLSRAEQIKWQKYCHQQIDAKSAQFAEAIDSLFQIHHDNPEKVKLLENLTAYAAQIAEFQVVKHT
ANAQSEQLVSALNQVAEQGMDKAAKLEMLKALIK

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=467, Percent_Identity=56.745182012848, Blast_Score=560, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 58469; Mature: 58469

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNLTFFFYDYESFGVSPALDRPAQFACIRTDSDFNIIGEPVMFYCKQTPDYLPSPEAV
CCCCEEEEEEEHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCEE
MVTGITPQQCNAEGVPEPEFAARIHAEFSQPNTCILGYNNIRYDDEMTRYTFFRNFFDPY
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCC
EYSWKNGNSRWDLLDLVRACYALRPDGIEWVIDENGVPNFKLENLTKANGIAHENAHDAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHH
ADVYATIAMAKLIKQKQPKLFQFFFENRGKKEIEKMIDTGEMTPLVHVSGMFGNARANTA
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCE
WIAPIAWHPTNQNQVLCCDLSGDVSALLTDSAEELRTRLYTKKEELAEAVAPVPLKGVHI
EEEEEEECCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
NRCPIIAPAKVLLPENAARLGIDRERCLENLKLLKANKSLVREKVTEIFMEERSFEPSAN
CCCCCCCCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VETTLYDGFFSPADKNNMAILRTLPPQELAHHGLQFADERVEALLFHYRARHYPETLSRA
CEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EQIKWQKYCHQQIDAKSAQFAEAIDSLFQIHHDNPEKVKLLENLTAYAAQIAEFQVVKHT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAQSEQLVSALNQVAEQGMDKAAKLEMLKALIK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MNKNLTFFFYDYESFGVSPALDRPAQFACIRTDSDFNIIGEPVMFYCKQTPDYLPSPEAV
CCCCEEEEEEEHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCEE
MVTGITPQQCNAEGVPEPEFAARIHAEFSQPNTCILGYNNIRYDDEMTRYTFFRNFFDPY
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCC
EYSWKNGNSRWDLLDLVRACYALRPDGIEWVIDENGVPNFKLENLTKANGIAHENAHDAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHH
ADVYATIAMAKLIKQKQPKLFQFFFENRGKKEIEKMIDTGEMTPLVHVSGMFGNARANTA
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCE
WIAPIAWHPTNQNQVLCCDLSGDVSALLTDSAEELRTRLYTKKEELAEAVAPVPLKGVHI
EEEEEEECCCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
NRCPIIAPAKVLLPENAARLGIDRERCLENLKLLKANKSLVREKVTEIFMEERSFEPSAN
CCCCCCCCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VETTLYDGFFSPADKNNMAILRTLPPQELAHHGLQFADERVEALLFHYRARHYPETLSRA
CEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EQIKWQKYCHQQIDAKSAQFAEAIDSLFQIHHDNPEKVKLLENLTAYAAQIAEFQVVKHT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANAQSEQLVSALNQVAEQGMDKAAKLEMLKALIK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]