Click here to switch to the map view.

The map label for this gene is accD

Identifier: 126208113

GI number: 126208113

Start: 718567

End: 719460

Strand: Direct

Name: accD

Synonym: APL_0631

Alternate gene names: 126208113

Gene position: 718567-719460 (Clockwise)

Preceding gene: 126208106

Following gene: 126208114

Centisome position: 31.59

GC content: 42.73

Gene sequence:

>894_bases
ATGAGCTGGATTGAAAGAATTTTAGGTAGAACCTCTTCATCGTCAAGCAGTAGCAAATCTAAAGTGCCGGAAGGCGTTTG
GACAAAATGTACCAGCTGTGAACAGGTGCTATACAGCGAAGAACTTAAACGTAATATGCACGTTTGCCCGAAATGTAATC
ACCATATGCGTTTTGATGCACGTACTCGTTTATTATCGTTATTAGACCAAGATAGCGCACAAGAGATTGCGGCGGAATTA
GAACCGCAAGACGTCTTAAAATTTAAAGATTTAAAAAAATATAAAGATCGTTTAACCGCAGCGCAAAAACAAACCGGTGA
GAAAGACTCTTTTATTACCATGTACGGTACGTTACATAATATGCCGGTAGTTGTCGCATCATTTAACTTTGAATTTATGG
GCGGCTCAATGGGCTCGGTTGTCGGTGCGAAATTCGTGCGTGCGGCGGAGCGAGCTTTAGCGGACAATATTCCGTTTATC
TGTTTCTCGGCATCCGGCGGTGCTCGTATGCAAGAAGCATTGTTCTCTTTAATGCAAATGGCGAAAACCAGTGCGATTTT
AGCGAAAATGCGTGAAAAAGGCATACCGTTTATTTCCATATTAACCGACCCGACATTAGGTGGCGTTTCGGCAAGTTTAG
CGATGTTAGGCGATATTAATATTGCGGAGCCTAAAGCGTTAATCGGTTTTGCCGGCCCGCGTGTTATCGAACAAACCGTA
CGCGAAAAACTACCGGAAGGTTTCCAACGTGCAGAGTTCTTATTAGAACACGGTGCGATTGATATGATTGTGCAACGTAA
AGATATGCGTGATACGCTTGCTCGTTTATGTGCAAAAATGACTAACAAGCCAACGCCTTTTAAAACGGCAGAATTAATTG
TTGAAGAAGCCTAA

Upstream 100 bases:

>100_bases
TTCGGCTGATCAGAGCAGATTGTATGACTAAAGCATATTCAAAAGGCTGAAATTATGCTTTAATAACAATAATTTTTTGT
CAAAAGAATAAGGTTAAAAA

Downstream 100 bases:

>100_bases
TTTTATTTAAGCATAACTTAAGCCACGTAATACGTGGCTTTCTTTTTGAGAACGATATGATGAATACTTTAACTGTTCCG
ACTATTAATGATTGCCTCGC

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSWIERILGRTSSSSSSSKSKVPEGVWTKCTSCEQVLYSEELKRNMHVCPKCNHHMRFDARTRLLSLLDQDSAQEIAAEL
EPQDVLKFKDLKKYKDRLTAAQKQTGEKDSFITMYGTLHNMPVVVASFNFEFMGGSMGSVVGAKFVRAAERALADNIPFI
CFSASGGARMQEALFSLMQMAKTSAILAKMREKGIPFISILTDPTLGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTV
REKLPEGFQRAEFLLEHGAIDMIVQRKDMRDTLARLCAKMTNKPTPFKTAELIVEEA

Sequences:

>Translated_297_residues
MSWIERILGRTSSSSSSSKSKVPEGVWTKCTSCEQVLYSEELKRNMHVCPKCNHHMRFDARTRLLSLLDQDSAQEIAAEL
EPQDVLKFKDLKKYKDRLTAAQKQTGEKDSFITMYGTLHNMPVVVASFNFEFMGGSMGSVVGAKFVRAAERALADNIPFI
CFSASGGARMQEALFSLMQMAKTSAILAKMREKGIPFISILTDPTLGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTV
REKLPEGFQRAEFLLEHGAIDMIVQRKDMRDTLARLCAKMTNKPTPFKTAELIVEEA
>Mature_296_residues
SWIERILGRTSSSSSSSKSKVPEGVWTKCTSCEQVLYSEELKRNMHVCPKCNHHMRFDARTRLLSLLDQDSAQEIAAELE
PQDVLKFKDLKKYKDRLTAAQKQTGEKDSFITMYGTLHNMPVVVASFNFEFMGGSMGSVVGAKFVRAAERALADNIPFIC
FSASGGARMQEALFSLMQMAKTSAILAKMREKGIPFISILTDPTLGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVR
EKLPEGFQRAEFLLEHGAIDMIVQRKDMRDTLARLCAKMTNKPTPFKTAELIVEEA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=286, Percent_Identity=71.6783216783217, Blast_Score=433, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_ACTP2 (A3MZZ7)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053338.1
- ProteinModelPortal:   A3MZZ7
- SMR:   A3MZZ7
- STRING:   A3MZZ7
- GeneID:   4848891
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0631
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- PhylomeDB:   A3MZZ7
- ProtClustDB:   PRK05654
- BioCyc:   APLE416269:APL_0631-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32907; Mature: 32775

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWIERILGRTSSSSSSSKSKVPEGVWTKCTSCEQVLYSEELKRNMHVCPKCNHHMRFDA
CCHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RTRLLSLLDQDSAQEIAAELEPQDVLKFKDLKKYKDRLTAAQKQTGEKDSFITMYGTLHN
HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCC
MPVVVASFNFEFMGGSMGSVVGAKFVRAAERALADNIPFICFSASGGARMQEALFSLMQM
CCEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
AKTSAILAKMREKGIPFISILTDPTLGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTV
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHH
REKLPEGFQRAEFLLEHGAIDMIVQRKDMRDTLARLCAKMTNKPTPFKTAELIVEEA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
SWIERILGRTSSSSSSSKSKVPEGVWTKCTSCEQVLYSEELKRNMHVCPKCNHHMRFDA
CHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RTRLLSLLDQDSAQEIAAELEPQDVLKFKDLKKYKDRLTAAQKQTGEKDSFITMYGTLHN
HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCC
MPVVVASFNFEFMGGSMGSVVGAKFVRAAERALADNIPFICFSASGGARMQEALFSLMQM
CCEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
AKTSAILAKMREKGIPFISILTDPTLGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTV
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHH
REKLPEGFQRAEFLLEHGAIDMIVQRKDMRDTLARLCAKMTNKPTPFKTAELIVEEA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA