Click here to switch to the map view.

The map label for this gene is tdk [H]

Identifier: 126208104

GI number: 126208104

Start: 710274

End: 710855

Strand: Reverse

Name: tdk [H]

Synonym: APL_0622

Alternate gene names: 126208104

Gene position: 710855-710274 (Counterclockwise)

Preceding gene: 126208105

Following gene: 126208097

Centisome position: 31.25

GC content: 40.21

Gene sequence:

>582_bases
ATGGCAAAACTCTATTTTTATTACTCCTCAATGAATGCGGGCAAATCAACCACCCTGCTTCAATCCTCTTATAATTACCA
AGAACGAGGTATGAATACGTTGGTTTATACCGCAGCGATTGATGATCGTTACGGCATCGGTAAAGTTAGTTCTCGTATCG
GAATTTCACAAGAAGCATTATTGTTTCAGTCGGACACTAATTTATTTAACGAAATCGAACTGGCTCATCAAACAGAAACG
TTACACTGTATCTTAATTGACGAAGCCCAATTTCTGACCAAAGCGCAGGTCTATCAATTAACCGACGTGGTGGATAAACT
TAAGATTCCGGTGCTTTGTTATGGTTTACGTACCGATTTCCAAGCCGAACTTTTTGAAGGCAGTCAATACCTATTGGCAT
GGGCGGACGAACTGCAAGAACTTAAAACGATTTGCGATTGCGGTCGAAAAGCGCATTTTGTGATTCGTATGAACGAAAAA
GGTGAAGCGGTCGCCGACGGAGACCAAATTCAAATCGGCGGAAATGATAAATATCTTTCCGTATGTCGTTATCATTACAA
ACAAAAACTCAATAAACTCTAA

Upstream 100 bases:

>100_bases
ATCGTTTACGTTCGCTTTTAGGTCAAATCGATAACGTATAATTGTTCCTTTTCAATAGAACGGCTAATTTGCATTAGCCG
TTTTTTATTTGTATAACATT

Downstream 100 bases:

>100_bases
TCTAATTTATAAGCGGTTGTTTTTACAAAAATTTTTACGAAAACAACCGCTTTTTCTTTATCTTTCTTTTCCTCTGTTTT
TATTTCCTGTATTTAAGTCT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MAKLYFYYSSMNAGKSTTLLQSSYNYQERGMNTLVYTAAIDDRYGIGKVSSRIGISQEALLFQSDTNLFNEIELAHQTET
LHCILIDEAQFLTKAQVYQLTDVVDKLKIPVLCYGLRTDFQAELFEGSQYLLAWADELQELKTICDCGRKAHFVIRMNEK
GEAVADGDQIQIGGNDKYLSVCRYHYKQKLNKL

Sequences:

>Translated_193_residues
MAKLYFYYSSMNAGKSTTLLQSSYNYQERGMNTLVYTAAIDDRYGIGKVSSRIGISQEALLFQSDTNLFNEIELAHQTET
LHCILIDEAQFLTKAQVYQLTDVVDKLKIPVLCYGLRTDFQAELFEGSQYLLAWADELQELKTICDCGRKAHFVIRMNEK
GEAVADGDQIQIGGNDKYLSVCRYHYKQKLNKL
>Mature_192_residues
AKLYFYYSSMNAGKSTTLLQSSYNYQERGMNTLVYTAAIDDRYGIGKVSSRIGISQEALLFQSDTNLFNEIELAHQTETL
HCILIDEAQFLTKAQVYQLTDVVDKLKIPVLCYGLRTDFQAELFEGSQYLLAWADELQELKTICDCGRKAHFVIRMNEKG
EAVADGDQIQIGGNDKYLSVCRYHYKQKLNKL

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=66.3157894736842, Blast_Score=280, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22041; Mature: 21910

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYFYYSSMNAGKSTTLLQSSYNYQERGMNTLVYTAAIDDRYGIGKVSSRIGISQEAL
CCEEEEEEECCCCCCCEEEEECCCCHHHCCCCEEEEEEEECCCCCCCCHHHHCCCCHHHE
LFQSDTNLFNEIELAHQTETLHCILIDEAQFLTKAQVYQLTDVVDKLKIPVLCYGLRTDF
EEECCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
QAELFEGSQYLLAWADELQELKTICDCGRKAHFVIRMNEKGEAVADGDQIQIGGNDKYLS
CHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCEEEECCCCCHHH
VCRYHYKQKLNKL
HHHHHHHHHHHCC
>Mature Secondary Structure 
AKLYFYYSSMNAGKSTTLLQSSYNYQERGMNTLVYTAAIDDRYGIGKVSSRIGISQEAL
CEEEEEEECCCCCCCEEEEECCCCHHHCCCCEEEEEEEECCCCCCCCHHHHCCCCHHHE
LFQSDTNLFNEIELAHQTETLHCILIDEAQFLTKAQVYQLTDVVDKLKIPVLCYGLRTDF
EEECCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
QAELFEGSQYLLAWADELQELKTICDCGRKAHFVIRMNEKGEAVADGDQIQIGGNDKYLS
CHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCEEEECCCCCHHH
VCRYHYKQKLNKL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA