Click here to switch to the map view.

The map label for this gene is pdxS

Identifier: 126208054

GI number: 126208054

Start: 645280

End: 646167

Strand: Direct

Name: pdxS

Synonym: APL_0572

Alternate gene names: 126208054

Gene position: 645280-646167 (Clockwise)

Preceding gene: 126208052

Following gene: 126208055

Centisome position: 28.37

GC content: 46.4

Gene sequence:

>888_bases
ATGACCAAAATTTTAGGTTCGGATCTGATTAAACGTGGAATGGCTCAAATGCAAAAAGGCGGAGTCATCATGGATGTAGT
GAATGCGGAACAAGCTCGTATCGCAGAAGCTGCCGGCGCGGTTGCTGTTATGGCGTTGGAACGTGTGCCTTCCGATATTC
GTGCTGCAGGCGGAGTAGCAAGAATGGCGAATACAGCTATTGTGCGTGAAGTGATGGAAGCGGTTTCTATTCCGGTAATG
GCAAAAGCACGTATCGGACATATTGTTGAGGCGAGAGTGCTGGAAGCAATGGGCGTAGATTATATTGATGAAAGTGAGGT
ATTAACGCCGGCAGATGAAGAGTTTCATTTGTTAAAAAGCGATTATACCGTGCCTTTTGTATGCGGCTGCCGAGATTTAG
GCGAAGCACTACGTCGTATCGGTGAAGGCGCTTCGATGTTGCGTACTAAAGGCGAACCGGGAACGGGCAATGTAGTGGAA
GCGGTTCGCCATTTACGCAAGGTCAATGCACAATTACGCAAAGTGATTAATATGAGTCATGATGAACTGATGACCGAAGC
AAAACACTTAGGCGCACCGTTTGAATTATTGTTACAAATTAAAACGTTAGGCAAATTACCGGTAGTAAATTTTGCGGCGG
GCGGAATTGCCACACCGGCGGATGCCGCATTAATGATGGAATTAGGCGCAGACGGCGTATTTGTCGGATCGGGGATTTTT
AAATCCGAAAATCCGGAGAAATTTGCAAAAGCGATTGTACAAGCTACCACTCATTATCAAGATTATGACTTAATCGCTCG
TCTTTCGGCGGATTTAGGCGAACCGATGAGAGGGTTGGAAATCAGCGAATTAGCGGTACAAGATCGTATGCAAGAGCGTG
GTTGGTAA

Upstream 100 bases:

>100_bases
ACTTCTGACCTCATTAATATTTATTAAATTGATGCTTTTAATCATATCTGTTTGAAATAAAAATAGCCATCATTTTCACA
TCAACAAGAAGGAAATTAAT

Downstream 100 bases:

>100_bases
TGAACGATTATACAAAATATACCATAGGCGTATTGTCATTACAGGGGGCGGTTTCGGAACATATCGCTCAAATAGAAACT
TTGGGCGCAAAAGCCATAGC

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTKILGSDLIKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVARMANTAIVREVMEAVSIPVM
AKARIGHIVEARVLEAMGVDYIDESEVLTPADEEFHLLKSDYTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNVVE
AVRHLRKVNAQLRKVINMSHDELMTEAKHLGAPFELLLQIKTLGKLPVVNFAAGGIATPADAALMMELGADGVFVGSGIF
KSENPEKFAKAIVQATTHYQDYDLIARLSADLGEPMRGLEISELAVQDRMQERGW

Sequences:

>Translated_295_residues
MTKILGSDLIKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVARMANTAIVREVMEAVSIPVM
AKARIGHIVEARVLEAMGVDYIDESEVLTPADEEFHLLKSDYTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNVVE
AVRHLRKVNAQLRKVINMSHDELMTEAKHLGAPFELLLQIKTLGKLPVVNFAAGGIATPADAALMMELGADGVFVGSGIF
KSENPEKFAKAIVQATTHYQDYDLIARLSADLGEPMRGLEISELAVQDRMQERGW
>Mature_294_residues
TKILGSDLIKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVARMANTAIVREVMEAVSIPVMA
KARIGHIVEARVLEAMGVDYIDESEVLTPADEEFHLLKSDYTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNVVEA
VRHLRKVNAQLRKVINMSHDELMTEAKHLGAPFELLLQIKTLGKLPVVNFAAGGIATPADAALMMELGADGVFVGSGIFK
SENPEKFAKAIVQATTHYQDYDLIARLSADLGEPMRGLEISELAVQDRMQERGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=295, Percent_Identity=56.6101694915254, Blast_Score=339, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6323996, Length=293, Percent_Identity=58.0204778156997, Blast_Score=338, Evalue=7e-94,
Organism=Saccharomyces cerevisiae, GI6321049, Length=293, Percent_Identity=58.0204778156997, Blast_Score=338, Evalue=8e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_ACTP2 (A3MZT8)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053279.1
- ProteinModelPortal:   A3MZT8
- SMR:   A3MZT8
- STRING:   A3MZT8
- GeneID:   4850439
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0572
- eggNOG:   COG0214
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- PhylomeDB:   A3MZT8
- ProtClustDB:   PRK04180
- BioCyc:   APLE416269:APL_0572-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31792; Mature: 31661

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILGSDLIKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVA
CCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHH
RMANTAIVREVMEAVSIPVMAKARIGHIVEARVLEAMGVDYIDESEVLTPADEEFHLLKS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHC
DYTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNVVEAVRHLRKVNAQLRKVINMSH
CCCCEEEECCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
DELMTEAKHLGAPFELLLQIKTLGKLPVVNFAAGGIATPADAALMMELGADGVFVGSGIF
HHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSENPEKFAKAIVQATTHYQDYDLIARLSADLGEPMRGLEISELAVQDRMQERGW
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKILGSDLIKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVA
CCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHH
RMANTAIVREVMEAVSIPVMAKARIGHIVEARVLEAMGVDYIDESEVLTPADEEFHLLKS
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHC
DYTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNVVEAVRHLRKVNAQLRKVINMSH
CCCCEEEECCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
DELMTEAKHLGAPFELLLQIKTLGKLPVVNFAAGGIATPADAALMMELGADGVFVGSGIF
HHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSENPEKFAKAIVQATTHYQDYDLIARLSADLGEPMRGLEISELAVQDRMQERGW
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA