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The map label for this gene is pyrH [H]

Identifier: 126208051

GI number: 126208051

Start: 642261

End: 642974

Strand: Direct

Name: pyrH [H]

Synonym: APL_0569

Alternate gene names: 126208051

Gene position: 642261-642974 (Clockwise)

Preceding gene: 126208049

Following gene: 126208052

Centisome position: 28.24

GC content: 43.98

Gene sequence:

>714_bases
ATGAGCAACCCAATCTATAAACGTATTTTATTAAAATTAAGCGGCGAGGCATTACAAGGCGATGAAGGCTTCGGTATTGA
TCCGTCTATTTTGGATCGTATGGCATTAGAAATTAAAGAATTGATTGAAATGGGTGTGGAAGTCGGTGTGGTACTCGGCG
GCGGTAACTTATTCCGCGGTGCGAAATTAGCGAAAGCCGGTATGAACCGTGTTGTGGGCGACCATATGGGTATGCTTGCA
ACCGTGATGAACGGTTTGGCAATGCGTGATGCGTTACACCGTGCGGATGTTAATGCAAAATTAATGTCGGCATTCCAATT
AAACGGTATTTGCGATACTTATAACTGGTCCGAAGCAATCAAAATGTTACGTGAAAAACGTGTGGTAATTTTCTCTGCAG
GTACCGGTAGCCCGTTCTTTACTACGGATTCCGCAGCTTGTTTACGCGGTATCGAAATCGAAGCGGACATCGTCTTAAAA
GCAACTAAAGTGGACGGCGTATATGATAAAGATCCGGCTAAATTTGCCGATGCGAAACTGTATAATCAATTAACTTATGC
GGAAGTCATCGAGCAAGAATTACAAGTAATGGACTTAGCTGCGTTTACGTTAGCGCGCGACCACGGTATGCCGATTCGCG
TATTCAATATGGTGAAACCGGGCGCATTAAAACAAGTGATTACCGGTACGGCCGAAGGTACGATTATTTCTTAA

Upstream 100 bases:

>100_bases
AATTATAAATATGATTTCTTATTTATTTCCTGTTTAAATCGGATGGTCTATAATAGCGTAATTTTGTTTTTAGTCCATAC
AGCATTAAGAGGCAATTAAA

Downstream 100 bases:

>100_bases
TAACCCGTATGCGATACAAGCGGTCTGTATTCTTTACTTATTTGCAAATAAAGAAAGCAGACCGTTTTTTGTTTGCTCGT
CACTGTTCGGTAAGCGAGAA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSNPIYKRILLKLSGEALQGDEGFGIDPSILDRMALEIKELIEMGVEVGVVLGGGNLFRGAKLAKAGMNRVVGDHMGMLA
TVMNGLAMRDALHRADVNAKLMSAFQLNGICDTYNWSEAIKMLREKRVVIFSAGTGSPFFTTDSAACLRGIEIEADIVLK
ATKVDGVYDKDPAKFADAKLYNQLTYAEVIEQELQVMDLAAFTLARDHGMPIRVFNMVKPGALKQVITGTAEGTIIS

Sequences:

>Translated_237_residues
MSNPIYKRILLKLSGEALQGDEGFGIDPSILDRMALEIKELIEMGVEVGVVLGGGNLFRGAKLAKAGMNRVVGDHMGMLA
TVMNGLAMRDALHRADVNAKLMSAFQLNGICDTYNWSEAIKMLREKRVVIFSAGTGSPFFTTDSAACLRGIEIEADIVLK
ATKVDGVYDKDPAKFADAKLYNQLTYAEVIEQELQVMDLAAFTLARDHGMPIRVFNMVKPGALKQVITGTAEGTIIS
>Mature_236_residues
SNPIYKRILLKLSGEALQGDEGFGIDPSILDRMALEIKELIEMGVEVGVVLGGGNLFRGAKLAKAGMNRVVGDHMGMLAT
VMNGLAMRDALHRADVNAKLMSAFQLNGICDTYNWSEAIKMLREKRVVIFSAGTGSPFFTTDSAACLRGIEIEADIVLKA
TKVDGVYDKDPAKFADAKLYNQLTYAEVIEQELQVMDLAAFTLARDHGMPIRVFNMVKPGALKQVITGTAEGTIIS

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=236, Percent_Identity=78.3898305084746, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25701; Mature: 25570

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPIYKRILLKLSGEALQGDEGFGIDPSILDRMALEIKELIEMGVEVGVVLGGGNLFRG
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHH
AKLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRADVNAKLMSAFQLNGICDTYNWSEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHH
KMLREKRVVIFSAGTGSPFFTTDSAACLRGIEIEADIVLKATKVDGVYDKDPAKFADAKL
HHHHHCCEEEEECCCCCCCEECCHHHHHHCCEEEEEEEEEEEECCCCCCCCCHHHHHHHH
YNQLTYAEVIEQELQVMDLAAFTLARDHGMPIRVFNMVKPGALKQVITGTAEGTIIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCEEC
>Mature Secondary Structure 
SNPIYKRILLKLSGEALQGDEGFGIDPSILDRMALEIKELIEMGVEVGVVLGGGNLFRG
CCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHH
AKLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRADVNAKLMSAFQLNGICDTYNWSEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHH
KMLREKRVVIFSAGTGSPFFTTDSAACLRGIEIEADIVLKATKVDGVYDKDPAKFADAKL
HHHHHCCEEEEECCCCCCCEECCHHHHHHCCEEEEEEEEEEEECCCCCCCCCHHHHHHHH
YNQLTYAEVIEQELQVMDLAAFTLARDHGMPIRVFNMVKPGALKQVITGTAEGTIIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA