Click here to switch to the map view.

The map label for this gene is cdsA [H]

Identifier: 126207897

GI number: 126207897

Start: 471390

End: 472259

Strand: Reverse

Name: cdsA [H]

Synonym: APL_0413

Alternate gene names: 126207897

Gene position: 472259-471390 (Counterclockwise)

Preceding gene: 126207898

Following gene: 126207896

Centisome position: 20.76

GC content: 42.87

Gene sequence:

>870_bases
ATGCTTAAAGAACGAGTACTTTCTGCGATTGTGATGGTTATTGCCGTCTTAGCAGGTATCTTCTTACTTTCTCCGCTCCC
TCTTACCATTGCCTTAGCCGCAATTATTACCGCTGCAATGTGGGAATGGGCGCAATTTGCCGGCTTTAAACGTTCATTAC
CTAGAGCGGTTGTGGCATTCGTTACGGTTTGTTTATTTATCTTATTAATTTTCGCCAATACCAACTACATTAGAGCGGCT
CGTTTCCTAACGGACGAAACCGTTCCGCTCCTGTTTATTTCATGCGTCTGGTGGTTAATCGCCTTTATTTTAGTCGTCAC
TTATCCTCGTTCCGCAAATGTTTGGGCAAAATCCGTTATTGCTAAATTTATTTTCGGGTTCTGTACGCTTATTCCCTTCT
TTATTGCTGCGCTCGCGTTACGTTTTAATAATTATGCGGTAGATGAATTCCAAGGAACTTATTTATTACTTTATGTTTGT
TTACTGGTTTGGGGAGCCGATTCCGGAGCCTATTTCTTCGGTCGAGCATTCGGTAAACATAAACTTGCGCCGAAAGTTTC
GCCGGGAAAATCTTGGGAAGGTGCAATCGGCGGTTTGATTACTTCGTGCGTGATCGCATTCCTTTTCTTAGAACTGGCAC
CGAGCGATGTATTCGGACGTGAATTATCCACCGTACCCTTTATTTTAGTTTCCGTCGCAACGGTTGCGATTTCCGTATTA
GGCGATTTGGCGGAAAGTATGTTTAAACGCCAAGCGAATATTAAAGACAGCAGCAATTTAATTCCGGGACACGGCGGTAT
TTTAGATCGAATTGACAGCTTAACTGCGGCGATTCCGTTCTTTACCACTTTCTTTTTCTTTGTATTATAG

Upstream 100 bases:

>100_bases
GGATTTTAATGATGACTCTTTTAGTGAAGCCATCATTGCTTATCAACAACGTGATCGTCGTTTCGGCGGTTGTTAATAAA
ATAATTATAAGGATTTTTTA

Downstream 100 bases:

>100_bases
GATGTTATGACCTCTGTTATTGCATTTTTCATCTTAATTTGCGTACTGGTTTTTGTACATGAATACGGTCACTTTTGGGC
TGCTCGTAAATGCGGCGTCA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLKERVLSAIVMVIAVLAGIFLLSPLPLTIALAAIITAAMWEWAQFAGFKRSLPRAVVAFVTVCLFILLIFANTNYIRAA
RFLTDETVPLLFISCVWWLIAFILVVTYPRSANVWAKSVIAKFIFGFCTLIPFFIAALALRFNNYAVDEFQGTYLLLYVC
LLVWGADSGAYFFGRAFGKHKLAPKVSPGKSWEGAIGGLITSCVIAFLFLELAPSDVFGRELSTVPFILVSVATVAISVL
GDLAESMFKRQANIKDSSNLIPGHGGILDRIDSLTAAIPFFTTFFFFVL

Sequences:

>Translated_289_residues
MLKERVLSAIVMVIAVLAGIFLLSPLPLTIALAAIITAAMWEWAQFAGFKRSLPRAVVAFVTVCLFILLIFANTNYIRAA
RFLTDETVPLLFISCVWWLIAFILVVTYPRSANVWAKSVIAKFIFGFCTLIPFFIAALALRFNNYAVDEFQGTYLLLYVC
LLVWGADSGAYFFGRAFGKHKLAPKVSPGKSWEGAIGGLITSCVIAFLFLELAPSDVFGRELSTVPFILVSVATVAISVL
GDLAESMFKRQANIKDSSNLIPGHGGILDRIDSLTAAIPFFTTFFFFVL
>Mature_289_residues
MLKERVLSAIVMVIAVLAGIFLLSPLPLTIALAAIITAAMWEWAQFAGFKRSLPRAVVAFVTVCLFILLIFANTNYIRAA
RFLTDETVPLLFISCVWWLIAFILVVTYPRSANVWAKSVIAKFIFGFCTLIPFFIAALALRFNNYAVDEFQGTYLLLYVC
LLVWGADSGAYFFGRAFGKHKLAPKVSPGKSWEGAIGGLITSCVIAFLFLELAPSDVFGRELSTVPFILVSVATVAISVL
GDLAESMFKRQANIKDSSNLIPGHGGILDRIDSLTAAIPFFTTFFFFVL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=288, Percent_Identity=47.5694444444444, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1787677, Length=122, Percent_Identity=38.5245901639344, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31765; Mature: 31765

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]