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The map label for this gene is fabZ

Identifier: 126207892

GI number: 126207892

Start: 465147

End: 465611

Strand: Reverse

Name: fabZ

Synonym: APL_0408

Alternate gene names: 126207892

Gene position: 465611-465147 (Counterclockwise)

Preceding gene: 126207893

Following gene: 126207891

Centisome position: 20.47

GC content: 39.57

Gene sequence:

>465_bases
ATGACTATTGAAGTACAAGAAAATAGAGAACCTAAAATTATTGAAGTAACGGAAATTATGAAAATGTTACCTCATCGCTA
TCCTTTCTTACTTGTAGATCGTGTTATTGATTTTGAAGAAGGCAAATGGCTGAAAGCAATTAAAAACGTGACCGTAAACG
AACCTTGTTTTACCGGTCACTTCCCTGAAAGTCCGATTTTCCCTGGCGTACTTATTTTAGAAGCGATGGCGCAAGCAACC
GGCGTATTAGCGGTCGCGACACACGGAAAAATGGCGCAAGACGAATTATATTATTTTGCGGCTATTGATAATGCTCGCTT
TAAGCGTCCGGTCGTGCCGGGTGACCAACTTACATTCGAAGTTGAATTTTTAAAAGAAATGCGTGGTATCACTAAATTTA
CCGGAAAAGCTTTTGTTGATGGAAAACTAGTGTGCGAAGCCGATTTAATGTGTGCACGTAAATAA

Upstream 100 bases:

>100_bases
TAAAAGCGATTGAAAAACGTTTAGCTGAATAAGCATTTTTTATGGGCTTACCGCTGTAAGCCTTATTTTAGTTTATACAT
TTTATTATGAGGCCGAATTA

Downstream 100 bases:

>100_bases
TTAAACTCCAACCTCACAGGAGAAACTATGCGATTAATTGATTCAACTGCAAAAATCAGTCCTTTAGCCGTCGTTGAAGA
AGGGGCGCAAATTGGCGCTC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTIEVQENREPKIIEVTEIMKMLPHRYPFLLVDRVIDFEEGKWLKAIKNVTVNEPCFTGHFPESPIFPGVLILEAMAQAT
GVLAVATHGKMAQDELYYFAAIDNARFKRPVVPGDQLTFEVEFLKEMRGITKFTGKAFVDGKLVCEADLMCARK

Sequences:

>Translated_154_residues
MTIEVQENREPKIIEVTEIMKMLPHRYPFLLVDRVIDFEEGKWLKAIKNVTVNEPCFTGHFPESPIFPGVLILEAMAQAT
GVLAVATHGKMAQDELYYFAAIDNARFKRPVVPGDQLTFEVEFLKEMRGITKFTGKAFVDGKLVCEADLMCARK
>Mature_153_residues
TIEVQENREPKIIEVTEIMKMLPHRYPFLLVDRVIDFEEGKWLKAIKNVTVNEPCFTGHFPESPIFPGVLILEAMAQATG
VLAVATHGKMAQDELYYFAAIDNARFKRPVVPGDQLTFEVEFLKEMRGITKFTGKAFVDGKLVCEADLMCARK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=141, Percent_Identity=68.0851063829787, Blast_Score=210, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_ACTP2 (A3MZC6)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053117.1
- ProteinModelPortal:   A3MZC6
- SMR:   A3MZC6
- STRING:   A3MZC6
- GeneID:   4850532
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0408
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   A3MZC6
- ProtClustDB:   PRK00006
- BioCyc:   APLE416269:APL_0408-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17481; Mature: 17350

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: ACT_SITE 60-60

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEVQENREPKIIEVTEIMKMLPHRYPFLLVDRVIDFEEGKWLKAIKNVTVNEPCFTGH
CEEEECCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
FPESPIFPGVLILEAMAQATGVLAVATHGKMAQDELYYFAAIDNARFKRPVVPGDQLTFE
CCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEE
VEFLKEMRGITKFTGKAFVDGKLVCEADLMCARK
HHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCC
>Mature Secondary Structure 
TIEVQENREPKIIEVTEIMKMLPHRYPFLLVDRVIDFEEGKWLKAIKNVTVNEPCFTGH
EEEECCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
FPESPIFPGVLILEAMAQATGVLAVATHGKMAQDELYYFAAIDNARFKRPVVPGDQLTFE
CCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEE
VEFLKEMRGITKFTGKAFVDGKLVCEADLMCARK
HHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA