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The map label for this gene is engA [H]

Identifier: 126207887

GI number: 126207887

Start: 457528

End: 459048

Strand: Reverse

Name: engA [H]

Synonym: APL_0403

Alternate gene names: 126207887

Gene position: 459048-457528 (Counterclockwise)

Preceding gene: 126207888

Following gene: 126207886

Centisome position: 20.18

GC content: 43.59

Gene sequence:

>1521_bases
ATGACTCCAGTTGTTGCCCTTGTCGGCAGACCGAATGTGGGTAAATCCACTTTATTTAACCGCTTAACCCGCACGCGCGA
TGCGTTGGTAGCGGACTTTCCGGGACTTACCCGTGACCGTAAATACGGTCATGCGAATATTGCCGGCTATGATTTTATCG
TGATTGACACCGGCGGGATCGACGGTACGGAAGAAGGCGTAGAAGAAAAAATGGCGGAACAATCGCTACTGGCGATTGAA
GAAGCGGATGTCGTGCTTTTCTTAGTGGATGCACGTGCCGGTTTAGTACCTGCCGATATCGGTATCGCTCAATATTTACG
TCAGCGTGAAAAAACCACCGTGGTGGTCGCCAACAAAACGGACGGTATCGATGCGGATTCACATTGTGCGGAATTTTATC
AATTAGGTTTAGGCGAAGTCGAACAGATAGCAGCGGCACAAGGTCGTGGCGTGACACAACTTATCGATCAAGTATTAGCC
CCGTTAGGCGAACAATTAAATGCGGATCAAGCGGTCGAAAACGAAGAAAATTCTGCAAATGAAGAAGCAGACGAATGGGA
TACTGACTTTGACTTCGAAAATGAAGATGATACCGCATTACTTGATGAAGCACTTGAAGAAGAAACCGAAGAGTCTATTG
AAGATAAAAATATCAAGATTGCCATCGTCGGTCGTCCGAATGTAGGTAAATCAACCTTAACCAACCGTATTCTCGGTGAA
GAACGCGTGGTGGTTTACGATATGCCGGGGACGACACGTGATTCAATCTATATTCCAATGGAGCGTGACGGTCAGCAATA
TACGATTATCGACACGGCAGGTGTACGTAAACGTGGTAAAGTTAATTTAGCGGTAGAAAAATTCTCCGTGATTAAAACCC
TACAAGCGATTCAAGATGCGAATGTGGTATTACTTACCATTGATGCGCGTGAAGGAATTTCCGATCAAGATTTATCTCTA
CTCGGCTTTATTCTGAATGCCGGTCGTTCACTTGTGATCGTCGTGAATAAATGGGACGGTTTATCACAAGATATAAAAGA
TCAAGTGAAATCCGAATTAGACCGCCGTTTAGACTTTATTGATTTCGCACGTGTGCATTTTATTTCTGCATTACACGGCT
CAGGCGTAGGTAACTTATTTGATTCTGTTAAAGAAGCCTATGCGTGTGCAACACAAAAAACTTCGACTTCGATGTTAACG
CGTATTTTACGTATGGCTGCGGATGAGCATCAGCCGCCGTTAGTAAACGGTCGCCGTGTGAAATTAAAATACGCTCACCC
GGGCGGTTATAATCCGCCGATTATCGTGATTCACGGTAACCAAGTCGAAAAATTAGCGGATTCTTACAAACGTTATTTAA
GCAATTACTTCCGTAAGAGCTTGAAAATTATCGGTTCTCCGATCCGTATTCAGTTCCAAGAAGGTAATAACCCGTTTGCG
GGTAAGAAAAATAAACTTACGCCAAACCAATTACGTAAACGTAAACGTTTGATGAAGTTTATTAAGAAAAGTAAGAAATA
A

Upstream 100 bases:

>100_bases
CCGCTTTTTTTGATCCTTTTTCCGTTCTCAACGCTTTTAGTATATAATATGACAATTTTGCGACTCGCAAAGACAGAATT
TTTAGAAGGACAGAATAAGA

Downstream 100 bases:

>100_bases
TTAGATACTCTCTCCCGACTTTATGTTAGCGCTCGGCTATAACGAGTGCTATCTAAATAAGGTTTAAGGCACTCGTCACA
GACGAGCGCCATCTTTTAAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHANIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAIE
EADVVLFLVDARAGLVPADIGIAQYLRQREKTTVVVANKTDGIDADSHCAEFYQLGLGEVEQIAAAQGRGVTQLIDQVLA
PLGEQLNADQAVENEENSANEEADEWDTDFDFENEDDTALLDEALEEETEESIEDKNIKIAIVGRPNVGKSTLTNRILGE
ERVVVYDMPGTTRDSIYIPMERDGQQYTIIDTAGVRKRGKVNLAVEKFSVIKTLQAIQDANVVLLTIDAREGISDQDLSL
LGFILNAGRSLVIVVNKWDGLSQDIKDQVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSVKEAYACATQKTSTSMLT
RILRMAADEHQPPLVNGRRVKLKYAHPGGYNPPIIVIHGNQVEKLADSYKRYLSNYFRKSLKIIGSPIRIQFQEGNNPFA
GKKNKLTPNQLRKRKRLMKFIKKSKK

Sequences:

>Translated_506_residues
MTPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHANIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAIE
EADVVLFLVDARAGLVPADIGIAQYLRQREKTTVVVANKTDGIDADSHCAEFYQLGLGEVEQIAAAQGRGVTQLIDQVLA
PLGEQLNADQAVENEENSANEEADEWDTDFDFENEDDTALLDEALEEETEESIEDKNIKIAIVGRPNVGKSTLTNRILGE
ERVVVYDMPGTTRDSIYIPMERDGQQYTIIDTAGVRKRGKVNLAVEKFSVIKTLQAIQDANVVLLTIDAREGISDQDLSL
LGFILNAGRSLVIVVNKWDGLSQDIKDQVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSVKEAYACATQKTSTSMLT
RILRMAADEHQPPLVNGRRVKLKYAHPGGYNPPIIVIHGNQVEKLADSYKRYLSNYFRKSLKIIGSPIRIQFQEGNNPFA
GKKNKLTPNQLRKRKRLMKFIKKSKK
>Mature_505_residues
TPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHANIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAIEE
ADVVLFLVDARAGLVPADIGIAQYLRQREKTTVVVANKTDGIDADSHCAEFYQLGLGEVEQIAAAQGRGVTQLIDQVLAP
LGEQLNADQAVENEENSANEEADEWDTDFDFENEDDTALLDEALEEETEESIEDKNIKIAIVGRPNVGKSTLTNRILGEE
RVVVYDMPGTTRDSIYIPMERDGQQYTIIDTAGVRKRGKVNLAVEKFSVIKTLQAIQDANVVLLTIDAREGISDQDLSLL
GFILNAGRSLVIVVNKWDGLSQDIKDQVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSVKEAYACATQKTSTSMLTR
ILRMAADEHQPPLVNGRRVKLKYAHPGGYNPPIIVIHGNQVEKLADSYKRYLSNYFRKSLKIIGSPIRIQFQEGNNPFAG
KKNKLTPNQLRKRKRLMKFIKKSKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=505, Percent_Identity=72.4752475247525, Blast_Score=733, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=113, Percent_Identity=38.0530973451327, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=156, Percent_Identity=30.1282051282051, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 56189; Mature: 56058

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHANIAGYDFIVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCC
DGTEEGVEEKMAEQSLLAIEEADVVLFLVDARAGLVPADIGIAQYLRQREKTTVVVANKT
CCCHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECC
DGIDADSHCAEFYQLGLGEVEQIAAAQGRGVTQLIDQVLAPLGEQLNADQAVENEENSAN
CCCCCHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
EEADEWDTDFDFENEDDTALLDEALEEETEESIEDKNIKIAIVGRPNVGKSTLTNRILGE
CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCC
ERVVVYDMPGTTRDSIYIPMERDGQQYTIIDTAGVRKRGKVNLAVEKFSVIKTLQAIQDA
CCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHCCC
NVVLLTIDAREGISDQDLSLLGFILNAGRSLVIVVNKWDGLSQDIKDQVKSELDRRLDFI
CEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHH
DFARVHFISALHGSGVGNLFDSVKEAYACATQKTSTSMLTRILRMAADEHQPPLVNGRRV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCEE
KLKYAHPGGYNPPIIVIHGNQVEKLADSYKRYLSNYFRKSLKIIGSPIRIQFQEGNNPFA
EEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
GKKNKLTPNQLRKRKRLMKFIKKSKK
CCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHANIAGYDFIVIDTGGI
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCC
DGTEEGVEEKMAEQSLLAIEEADVVLFLVDARAGLVPADIGIAQYLRQREKTTVVVANKT
CCCHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECC
DGIDADSHCAEFYQLGLGEVEQIAAAQGRGVTQLIDQVLAPLGEQLNADQAVENEENSAN
CCCCCHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
EEADEWDTDFDFENEDDTALLDEALEEETEESIEDKNIKIAIVGRPNVGKSTLTNRILGE
CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCC
ERVVVYDMPGTTRDSIYIPMERDGQQYTIIDTAGVRKRGKVNLAVEKFSVIKTLQAIQDA
CCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHCCC
NVVLLTIDAREGISDQDLSLLGFILNAGRSLVIVVNKWDGLSQDIKDQVKSELDRRLDFI
CEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHH
DFARVHFISALHGSGVGNLFDSVKEAYACATQKTSTSMLTRILRMAADEHQPPLVNGRRV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCEE
KLKYAHPGGYNPPIIVIHGNQVEKLADSYKRYLSNYFRKSLKIIGSPIRIQFQEGNNPFA
EEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
GKKNKLTPNQLRKRKRLMKFIKKSKK
CCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA