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The map label for this gene is dhaL [H]

Identifier: 126207570

GI number: 126207570

Start: 90557

End: 91183

Strand: Reverse

Name: dhaL [H]

Synonym: APL_0082

Alternate gene names: 126207570

Gene position: 91183-90557 (Counterclockwise)

Preceding gene: 126207571

Following gene: 126207569

Centisome position: 4.01

GC content: 44.66

Gene sequence:

>627_bases
ATGGCGATTTCAAAACAACAAATCCTACAATGGCTTGAAAATTGTAATCAGGTGATGACTGAGCAACGAGATTTTCTCAC
ACAGTTGGATACCGAAATCGGTGACGGCGATCACGGTTTAAATATGCAACGAGGCTTTAGTAAGGCGTTAGAAAAAATTG
CTACCGTAAGCGATAAAGATATCGGTACGATCTTAAAAACGGTCGGTATGACATTACTCTCTCAAGTCGGCGGTGCAAGC
GGGCCTTTATACGGCACTTTATTTATCAAAGGTTCACAAGTTGCTAACGGTAAAGAACAACTAACTTTTGAAGAACTTGT
TAGCATCTTCAAAGCCGGCGTGGAAGGCATTATTGCGCGTGGGCGTGCAGAACCGGGTGATAAAACTCTGTGTGACGTTT
GGCTTCCGTTGCTTGATGAATTAGCCCAAGCGGATCACTCTCAGCCTGAAGCCGTTCTACTTAATCAAGCGGTCGAAAAA
GCCGAAAATTTTGCAAAAGCCACCGTGCCGATGACAGCTAAAAAAGGGCGAGCCAGCTATTTAGGCGAACGTAGCGTTGG
TCATGCGGATCCCGGCGCAACATCAAGCTATTATTTAATCAAAGCTTTAGCTGAAGCGGTTAAATAG

Upstream 100 bases:

>100_bases
ATGCAAGGTGTTTCTATTACCTTACTAAAAGTCGATGATGAAACCTTAGCACTTTGGGATGCACCGGTTAATACGCCGGC
ATTACGTTGGGGAGAATAAG

Downstream 100 bases:

>100_bases
GAGTAGTGATGGTTAATTTAGTGATTGTTTCGCATAGTAAACAGCTTGGAGAAGGCGTAGCGGAAATTACCCGCCAAATG
GCACAAGGTTCGTGCAAAAT

Product: dihydroxyacetone kinase subunit DhaL

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MAISKQQILQWLENCNQVMTEQRDFLTQLDTEIGDGDHGLNMQRGFSKALEKIATVSDKDIGTILKTVGMTLLSQVGGAS
GPLYGTLFIKGSQVANGKEQLTFEELVSIFKAGVEGIIARGRAEPGDKTLCDVWLPLLDELAQADHSQPEAVLLNQAVEK
AENFAKATVPMTAKKGRASYLGERSVGHADPGATSSYYLIKALAEAVK

Sequences:

>Translated_208_residues
MAISKQQILQWLENCNQVMTEQRDFLTQLDTEIGDGDHGLNMQRGFSKALEKIATVSDKDIGTILKTVGMTLLSQVGGAS
GPLYGTLFIKGSQVANGKEQLTFEELVSIFKAGVEGIIARGRAEPGDKTLCDVWLPLLDELAQADHSQPEAVLLNQAVEK
AENFAKATVPMTAKKGRASYLGERSVGHADPGATSSYYLIKALAEAVK
>Mature_207_residues
AISKQQILQWLENCNQVMTEQRDFLTQLDTEIGDGDHGLNMQRGFSKALEKIATVSDKDIGTILKTVGMTLLSQVGGASG
PLYGTLFIKGSQVANGKEQLTFEELVSIFKAGVEGIIARGRAEPGDKTLCDVWLPLLDELAQADHSQPEAVLLNQAVEKA
ENFAKATVPMTAKKGRASYLGERSVGHADPGATSSYYLIKALAEAVK

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Escherichia coli, GI1787449, Length=209, Percent_Identity=53.5885167464115, Blast_Score=238, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17565018, Length=210, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323570, Length=206, Percent_Identity=26.2135922330097, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 22396; Mature: 22265

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISKQQILQWLENCNQVMTEQRDFLTQLDTEIGDGDHGLNMQRGFSKALEKIATVSDKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCH
IGTILKTVGMTLLSQVGGASGPLYGTLFIKGSQVANGKEQLTFEELVSIFKAGVEGIIAR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHC
GRAEPGDKTLCDVWLPLLDELAQADHSQPEAVLLNQAVEKAENFAKATVPMTAKKGRASY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LGERSVGHADPGATSSYYLIKALAEAVK
HCCCCCCCCCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
AISKQQILQWLENCNQVMTEQRDFLTQLDTEIGDGDHGLNMQRGFSKALEKIATVSDKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCH
IGTILKTVGMTLLSQVGGASGPLYGTLFIKGSQVANGKEQLTFEELVSIFKAGVEGIIAR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHC
GRAEPGDKTLCDVWLPLLDELAQADHSQPEAVLLNQAVEKAENFAKATVPMTAKKGRASY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LGERSVGHADPGATSSYYLIKALAEAVK
HCCCCCCCCCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]