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The map label for this gene is mipB

Identifier: 126207550

GI number: 126207550

Start: 67907

End: 68854

Strand: Reverse

Name: mipB

Synonym: APL_0062

Alternate gene names: 126207550

Gene position: 68854-67907 (Counterclockwise)

Preceding gene: 126207557

Following gene: 126207547

Centisome position: 3.03

GC content: 40.51

Gene sequence:

>948_bases
ATGAGCCAATTAGATGCTTTACGTGAAATGACCGTTGTTGTTGCAGACACTGGTGACATTGAAGCGATCAAACAATATCA
ACCGCAAGATGCAACTACTAACCCGTCTTTAATTTTAAGTGCGTCTGCATTACCGCAATACGCTTCATTAATTGATGATG
CAGTAGCTTATGCTAAAGCAAGAAGTGATGATAAAGCCCAGCTACTTATTGATGCGGAAGATAAGTTAGCCGTGAATATT
GGTTTAGAAATTCTTAAAATCGTACCGGGACGTATTTCTACGGAAGTTGATGCTCGCCTTTCTTACGATACGAAAGCAAC
AATTGAGAAAGCTCGCCAAATTATGAAACTTTATAATGACGCTGGCATTAGTAATGATCGTATTCTTATTAAAATCGCTT
CAACTTGGCAAGGTATCCGTGCGGCGGAAGTGCTAGAGAAAGAAGGTATCAACTGTAACTTAACCTTATTATTCTCTCAA
GCGCAAGCTCGTGCGTGTGCGAAAGCAGGCGTTTACTTAATCTCTCCGTTTGTTGGTCGTATCTTAGACTGGTATAAAGC
AGCAGAGAAAAAAGAATATGCACCGGCAGAAGATCCGGGGGTAATTTCTGTTACAAATATCTATAACTACTACAAACAGT
ACGGCTATCAAACTGTGGTTATGGGCGCAAGTTTCCGTAACGTAGGTGAAATTACCGAAATCGCAGGCTGTGACCGTTTA
ACCATTGCTCCGCCATTATTAAAAGAACTTGCTGAAAGCAATGCCCCTCTTGTTCGTAAATTAGAATATAAAGGTGAAGT
GAAAACTCGTCCGGCACCATTAACAGAAGCGGAATTCTACTGGCAACATAACCAAGACCCAATGGCTGTTGAAAAATTAG
CGGAAGGTATCCGTAAATTTGCAGTAGATATTGAGAAATTAGAAGCAATGCTTGCCGCTAAACTTTAA

Upstream 100 bases:

>100_bases
TGATCTTCCTCACAAAATTATTCGTACTTTTTCCGGTAGTTATTGGTATTATATATGCCATTATCCTTATTCATCTATTA
TATATAAAGAGGAACCTTTT

Downstream 100 bases:

>100_bases
TTACTGAATTATTGAAACAAAAATCCCAAGCTGAGGCTTGGGATTTTTTTATGCTACTAGGTAAGCAAGCGGTCAATTTC
TCAGAATAATTTGTAAATTC

Product: transaldolase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSQLDALREMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYASLIDDAVAYAKARSDDKAQLLIDAEDKLAVNI
GLEILKIVPGRISTEVDARLSYDTKATIEKARQIMKLYNDAGISNDRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSQ
AQARACAKAGVYLISPFVGRILDWYKAAEKKEYAPAEDPGVISVTNIYNYYKQYGYQTVVMGASFRNVGEITEIAGCDRL
TIAPPLLKELAESNAPLVRKLEYKGEVKTRPAPLTEAEFYWQHNQDPMAVEKLAEGIRKFAVDIEKLEAMLAAKL

Sequences:

>Translated_315_residues
MSQLDALREMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYASLIDDAVAYAKARSDDKAQLLIDAEDKLAVNI
GLEILKIVPGRISTEVDARLSYDTKATIEKARQIMKLYNDAGISNDRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSQ
AQARACAKAGVYLISPFVGRILDWYKAAEKKEYAPAEDPGVISVTNIYNYYKQYGYQTVVMGASFRNVGEITEIAGCDRL
TIAPPLLKELAESNAPLVRKLEYKGEVKTRPAPLTEAEFYWQHNQDPMAVEKLAEGIRKFAVDIEKLEAMLAAKL
>Mature_314_residues
SQLDALREMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYASLIDDAVAYAKARSDDKAQLLIDAEDKLAVNIG
LEILKIVPGRISTEVDARLSYDTKATIEKARQIMKLYNDAGISNDRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSQA
QARACAKAGVYLISPFVGRILDWYKAAEKKEYAPAEDPGVISVTNIYNYYKQYGYQTVVMGASFRNVGEITEIAGCDRLT
IAPPLLKELAESNAPLVRKLEYKGEVKTRPAPLTEAEFYWQHNQDPMAVEKLAEGIRKFAVDIEKLEAMLAAKL

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=318, Percent_Identity=58.1761006289308, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI1786189, Length=311, Percent_Identity=77.491961414791, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1788807, Length=316, Percent_Identity=64.873417721519, Blast_Score=423, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI25153750, Length=319, Percent_Identity=56.1128526645768, Blast_Score=353, Evalue=7e-98,
Organism=Caenorhabditis elegans, GI25153752, Length=165, Percent_Identity=52.1212121212121, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17570473, Length=97, Percent_Identity=46.3917525773196, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321480, Length=320, Percent_Identity=52.8125, Blast_Score=329, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6323386, Length=310, Percent_Identity=58.0645161290323, Blast_Score=322, Evalue=5e-89,
Organism=Drosophila melanogaster, GI45549185, Length=319, Percent_Identity=57.6802507836991, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): TAL_ACTP2 (A3MYD4)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001052775.1
- ProteinModelPortal:   A3MYD4
- SMR:   A3MYD4
- STRING:   A3MYD4
- GeneID:   4848514
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0062
- eggNOG:   COG0176
- HOGENOM:   HBG286747
- OMA:   DTGDFHA
- PhylomeDB:   A3MYD4
- ProtClustDB:   PRK05269
- BioCyc:   APLE416269:APL_0062-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 34794; Mature: 34663

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLDALREMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYASLIDDAVAYAKA
CCHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHC
RSDDKAQLLIDAEDKLAVNIGLEILKIVPGRISTEVDARLSYDTKATIEKARQIMKLYND
CCCCCEEEEEECCCCEEEECCHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHH
AGISNDRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSQAQARACAKAGVYLISPFVGR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHH
ILDWYKAAEKKEYAPAEDPGVISVTNIYNYYKQYGYQTVVMGASFRNVGEITEIAGCDRL
HHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCE
TIAPPLLKELAESNAPLVRKLEYKGEVKTRPAPLTEAEFYWQHNQDPMAVEKLAEGIRKF
EECHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHHH
AVDIEKLEAMLAAKL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQLDALREMTVVVADTGDIEAIKQYQPQDATTNPSLILSASALPQYASLIDDAVAYAKA
CHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHC
RSDDKAQLLIDAEDKLAVNIGLEILKIVPGRISTEVDARLSYDTKATIEKARQIMKLYND
CCCCCEEEEEECCCCEEEECCHHHHHHCCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHH
AGISNDRILIKIASTWQGIRAAEVLEKEGINCNLTLLFSQAQARACAKAGVYLISPFVGR
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHH
ILDWYKAAEKKEYAPAEDPGVISVTNIYNYYKQYGYQTVVMGASFRNVGEITEIAGCDRL
HHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCE
TIAPPLLKELAESNAPLVRKLEYKGEVKTRPAPLTEAEFYWQHNQDPMAVEKLAEGIRKF
EECHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHHH
AVDIEKLEAMLAAKL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA