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The map label for this gene is narP [H]

Identifier: 126207547

GI number: 126207547

Start: 64259

End: 64888

Strand: Reverse

Name: narP [H]

Synonym: APL_0059

Alternate gene names: 126207547

Gene position: 64888-64259 (Counterclockwise)

Preceding gene: 126207550

Following gene: 126207546

Centisome position: 2.85

GC content: 40.32

Gene sequence:

>630_bases
ATGACCGAAGCTTATAAAATACTTTTAATTGACGATCATCCTTTAATGCGTCAGGGAATTAGACAAATTTTAGAATTAGA
AGATAACTTTGTTATCGTGGGTGAAGCAAGTAATGGCACGGACGGCATTAGTATCGCCTTAGATACAAACCCTGATTTAA
TTATCTTAGATTTAAATATGAAAGGAATTTCCGGTTTGGATACATTACGTGCATTAAGAAAGCACGGCATTGATAGCCGT
ATTGTCGTCTTAACCGTTTCGGACGAACAATCCGACGTATTCGCTTTAATGGACGCCGGTGTGGACGGTTATTTATTAAA
AGACAGCGATACCGCCGAGTTGGTCGAAAATATCCGAAAAGCGGCGCAAGGAGAAACGGTCTTAAGTGACAGCGTACGCC
AACATTTATTAGATCGTCGTCCGGAGAACGATCCGTTAAGCGTTTTAACCGATCGTGAACGCGATGTTCTACAATGGATC
GCAACCGGTATGTCCAATAAACAAATTGCCAGCCAATTATTTATTTCGGAAGAAACCGTTAAAGTACATATTCGTAACTT
ATTACGTAAATTAAACGTTCATTCTCGTGTGGCGGCTACCGTACTTTATCTCGAGCAACAAAAGGGTTAA

Upstream 100 bases:

>100_bases
CTTGGTGCAGATCAAAAATTAGTTGAATTACCCAAAATGGGTAACTTGCTTTAGTGAGATATAACAAGCACAATTTTTCC
TATTTCCGTTGGAGGTAACA

Downstream 100 bases:

>100_bases
TCCCAGCAAGCGGTTAAATTTACTAAAAAAGTGGCAAATTTAACCGCTTACTTGTACCGCTTAACTATGCAAGTCTATGT
AAAATCCATTCCTATTTTTA

Product: nitrate/nitrite response regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTEAYKILLIDDHPLMRQGIRQILELEDNFVIVGEASNGTDGISIALDTNPDLIILDLNMKGISGLDTLRALRKHGIDSR
IVVLTVSDEQSDVFALMDAGVDGYLLKDSDTAELVENIRKAAQGETVLSDSVRQHLLDRRPENDPLSVLTDRERDVLQWI
ATGMSNKQIASQLFISEETVKVHIRNLLRKLNVHSRVAATVLYLEQQKG

Sequences:

>Translated_209_residues
MTEAYKILLIDDHPLMRQGIRQILELEDNFVIVGEASNGTDGISIALDTNPDLIILDLNMKGISGLDTLRALRKHGIDSR
IVVLTVSDEQSDVFALMDAGVDGYLLKDSDTAELVENIRKAAQGETVLSDSVRQHLLDRRPENDPLSVLTDRERDVLQWI
ATGMSNKQIASQLFISEETVKVHIRNLLRKLNVHSRVAATVLYLEQQKG
>Mature_208_residues
TEAYKILLIDDHPLMRQGIRQILELEDNFVIVGEASNGTDGISIALDTNPDLIILDLNMKGISGLDTLRALRKHGIDSRI
VVLTVSDEQSDVFALMDAGVDGYLLKDSDTAELVENIRKAAQGETVLSDSVRQHLLDRRPENDPLSVLTDRERDVLQWIA
TGMSNKQIASQLFISEETVKVHIRNLLRKLNVHSRVAATVLYLEQQKG

Specific function: Could activate the expression of a formate dehydrogenase operon and could repress the transcription of the fumarate reductase (frdABCD) operon [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=59.4339622641509, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1787473, Length=211, Percent_Identity=44.5497630331754, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1788222, Length=202, Percent_Identity=32.6732673267327, Blast_Score=116, Evalue=8e-28,
Organism=Escherichia coli, GI1790102, Length=191, Percent_Identity=35.0785340314136, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=28.643216080402, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788712, Length=188, Percent_Identity=26.5957446808511, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI87082052, Length=118, Percent_Identity=36.4406779661017, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788546, Length=195, Percent_Identity=25.6410256410256, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23325; Mature: 23194

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAYKILLIDDHPLMRQGIRQILELEDNFVIVGEASNGTDGISIALDTNPDLIILDLNM
CCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEECC
KGISGLDTLRALRKHGIDSRIVVLTVSDEQSDVFALMDAGVDGYLLKDSDTAELVENIRK
CCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHH
AAQGETVLSDSVRQHLLDRRPENDPLSVLTDRERDVLQWIATGMSNKQIASQLFISEETV
HHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCHHHH
KVHIRNLLRKLNVHSRVAATVLYLEQQKG
HHHHHHHHHHHCHHHHHHHHHEEEECCCC
>Mature Secondary Structure 
TEAYKILLIDDHPLMRQGIRQILELEDNFVIVGEASNGTDGISIALDTNPDLIILDLNM
CCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEECC
KGISGLDTLRALRKHGIDSRIVVLTVSDEQSDVFALMDAGVDGYLLKDSDTAELVENIRK
CCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHH
AAQGETVLSDSVRQHLLDRRPENDPLSVLTDRERDVLQWIATGMSNKQIASQLFISEETV
HHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCHHHH
KVHIRNLLRKLNVHSRVAATVLYLEQQKG
HHHHHHHHHHHCHHHHHHHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]