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The map label for this gene is yrbI [C]

Identifier: 126207539

GI number: 126207539

Start: 57311

End: 57847

Strand: Reverse

Name: yrbI [C]

Synonym: APL_0051

Alternate gene names: 126207539

Gene position: 57847-57311 (Counterclockwise)

Preceding gene: 126207543

Following gene: 126207538

Centisome position: 2.54

GC content: 45.62

Gene sequence:

>537_bases
ATGGATTTAACTCAGATTAAATTAGTGATTACCGATGTGGACGGTGTGCTTACCGACGGTGGCATGTATTACACCGCAGA
AGGCGAAGTAATGAAACGCTTCCACGTCCATGACGGCTTAGGGATGAAAATGCTGCAAACCTGTGGAGTCCAAGTTGCAA
TTTTATCCGGCGGCGATTCGGCATTGTTGCGTAAACGTATTGATGTACTGAAAGTGCCTCTGTTTAAATTAGGCAAAATG
GAAAAACGTTCCGCCTGTTTTGAATTGATGAAAGAAGCCGGCGTAACAGCGGAACAAACGGCTTTTATCGGCGATGATAC
GTTAGATTTACCGGCATTTGAGGTTTGCGGACTGGCAATTGCTACCCGTAATGCGCACGACTATGTGAAAGCAAAAGCGG
ATTGGATATTAGAAAAGGCAGGTGGAGAGGGCGCATTTCGTGAAGTGTCCGACCGTATTCTACAAGCGCAAGGCTTTGAA
GAAATCTATGCGACTGCAGACGGTTTTCTAACCGTAGCTGAAAAAATGGCTCAGTAA

Upstream 100 bases:

>100_bases
GCTGAATTTGTTGCTTAATTTCAGATAAATTTTGAGAAATCGACATTTTTTACTCCAAAAACTATAATGGATAAATCATA
GCATATTGAGGAACAGAATA

Downstream 100 bases:

>100_bases
ATAAAGTATTAATAAAAAAATGGCATAGTAGACAAAAAGGTTGGTAAAAAGTGGGTTAAAGCCTTATAGTACAAGGCTTT
AACCTACCTTTTTGAAATAT

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MDLTQIKLVITDVDGVLTDGGMYYTAEGEVMKRFHVHDGLGMKMLQTCGVQVAILSGGDSALLRKRIDVLKVPLFKLGKM
EKRSACFELMKEAGVTAEQTAFIGDDTLDLPAFEVCGLAIATRNAHDYVKAKADWILEKAGGEGAFREVSDRILQAQGFE
EIYATADGFLTVAEKMAQ

Sequences:

>Translated_178_residues
MDLTQIKLVITDVDGVLTDGGMYYTAEGEVMKRFHVHDGLGMKMLQTCGVQVAILSGGDSALLRKRIDVLKVPLFKLGKM
EKRSACFELMKEAGVTAEQTAFIGDDTLDLPAFEVCGLAIATRNAHDYVKAKADWILEKAGGEGAFREVSDRILQAQGFE
EIYATADGFLTVAEKMAQ
>Mature_178_residues
MDLTQIKLVITDVDGVLTDGGMYYTAEGEVMKRFHVHDGLGMKMLQTCGVQVAILSGGDSALLRKRIDVLKVPLFKLGKM
EKRSACFELMKEAGVTAEQTAFIGDDTLDLPAFEVCGLAIATRNAHDYVKAKADWILEKAGGEGAFREVSDRILQAQGFE
EIYATADGFLTVAEKMAQ

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=152, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI2367202, Length=154, Percent_Identity=38.961038961039, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19412; Mature: 19412

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTQIKLVITDVDGVLTDGGMYYTAEGEVMKRFHVHDGLGMKMLQTCGVQVAILSGGDS
CCCCEEEEEEEECCCEEECCCEEEEECHHHHHHHHHCCCCCHHHHHHCCEEEEEEECCCH
ALLRKRIDVLKVPLFKLGKMEKRSACFELMKEAGVTAEQTAFIGDDTLDLPAFEVCGLAI
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCHHHHHHHHH
ATRNAHDYVKAKADWILEKAGGEGAFREVSDRILQAQGFEEIYATADGFLTVAEKMAQ
EECCCHHHHHHHHHHHHECCCCCCHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MDLTQIKLVITDVDGVLTDGGMYYTAEGEVMKRFHVHDGLGMKMLQTCGVQVAILSGGDS
CCCCEEEEEEEECCCEEECCCEEEEECHHHHHHHHHCCCCCHHHHHHCCEEEEEEECCCH
ALLRKRIDVLKVPLFKLGKMEKRSACFELMKEAGVTAEQTAFIGDDTLDLPAFEVCGLAI
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCHHHHHHHHH
ATRNAHDYVKAKADWILEKAGGEGAFREVSDRILQAQGFEEIYATADGFLTVAEKMAQ
EECCCHHHHHHHHHHHHECCCCCCHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12639950; 11835514 [H]